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. 1971 Mar;114(3):16–43.

The clinical physiology of calcium homeostasis, parathyroid hormone, and calcitonin. I.

C R Kleeman, S G Massry, J W Coburn
PMCID: PMC1501893  PMID: 5544688

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Selected References

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  1. Albright F., Bauer W., Claflin D., Cockrill J. R. STUDIES IN PARATHYROID PHYSIOLOGY: III. The Effect of Phosphate Ingestion in Clinical Hyperparathyroidism. J Clin Invest. 1932 Mar;11(2):411–435. doi: 10.1172/JCI100423. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Albright F., Bauer W., Ropes M., Aub J. C. STUDIES OF CALCIUM AND PHOSPHORUS METABOLISM: IV. The Effect of the Parathyroid Hormone. J Clin Invest. 1929 Apr;7(1):139–181. doi: 10.1172/JCI100218. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Aurbach G. D., Chase L. R. Cyclic 3',5'-adenylic acid in bone and the mechanism of action of parathyroid hormone. Fed Proc. 1970 May-Jun;29(3):1179–1182. [PubMed] [Google Scholar]
  4. Aurbach G. D., Potts J. T., Jr Parathyroid hormone. Am J Med. 1967 Jan;42(1):1–8. doi: 10.1016/0002-9343(67)90002-2. [DOI] [PubMed] [Google Scholar]
  5. BELL N. H., GERARD E. S., BARTTER F. C. PSEUDOHYPOPARATHYROIDISM WITH OSTEITIS FIBROSA CYSTICA AND IMPAIRED ABSORPTION OF CALCIUM. J Clin Endocrinol Metab. 1963 Aug;23:759–762. doi: 10.1210/jcem-23-8-759. [DOI] [PubMed] [Google Scholar]
  6. BERNSTEIN D., KLEEMAN C. R., ROCKNEY R., DOWLING J. T., MAXWELL M. H. Studies on the renal clearance of phosphate and the role of the parathyroid glands in its regulation. J Clin Endocrinol Metab. 1962 Jun;22:641–654. doi: 10.1210/jcem-22-6-641. [DOI] [PubMed] [Google Scholar]
  7. BUTCHER R. W., SUTHERLAND E. W. Adenosine 3',5'-phosphate in biological materials. I. Purification and properties of cyclic 3',5'-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3',5'-phosphate in human urine. J Biol Chem. 1962 Apr;237:1244–1250. [PubMed] [Google Scholar]
  8. Baylink D., Stauffer M., Wergedal J., Rich C. Formation, mineralization, and resorption of bone in vitamin D-deficient rats. J Clin Invest. 1970 Jun;49(6):1122–1134. doi: 10.1172/JCI106328. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Berson S. A., Yalow R. S. Radioimmunoassays of peptide hormones in plasma. N Engl J Med. 1967 Sep 21;277(12):640–647. doi: 10.1056/NEJM196709212771208. [DOI] [PubMed] [Google Scholar]
  10. Bethune J. E., Turpin R. A., Inoue H. Effect of parathyroid hormone extract on divalent ion excretion in man. J Clin Endocrinol Metab. 1968 May;28(5):673–678. doi: 10.1210/jcem-28-5-673. [DOI] [PubMed] [Google Scholar]
  11. Borle A. B. Effects of purified parathyroid hormone on the calcium metabolism of monkey kidney cells. Endocrinology. 1968 Dec;83(6):1316–1322. doi: 10.1210/endo-83-6-1316. [DOI] [PubMed] [Google Scholar]
  12. Borle A. B. Effects of thyrocalcitonin on calcium transport in kidney cells. Endocrinology. 1969 Aug;85(2):194–199. doi: 10.1210/endo-85-2-194. [DOI] [PubMed] [Google Scholar]
  13. Buckle R. M., Care A. D., Cooper C. W., Gitelman H. J. The influence of plasma magnesium concentration on parathyroid hormone secretion. J Endocrinol. 1968 Dec;42(4):529–534. doi: 10.1677/joe.0.0420529. [DOI] [PubMed] [Google Scholar]
  14. Buckle R. M. Radioimmunoassay of parathyroid hormone in primary hyperparathyroidism: studies after removal of parathyroid adenoma. Br Med J. 1969 Jun 28;2(5660):789–793. doi: 10.1136/bmj.2.5660.789. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Bussolati G., Pearse A. G. Immunofluorescent localization of calcitonin in the 'C' cells of pig and dog thyroid. J Endocrinol. 1967 Feb;37(2):205–209. doi: 10.1677/joe.0.0370205. [DOI] [PubMed] [Google Scholar]
  16. COPP D. H., CAMERON E. C., CHENEY B. A., DAVIDSON A. G., HENZE K. G. Evidence for calcitonin--a new hormone from the parathyroid that lowers blood calcium. Endocrinology. 1962 May;70:638–649. doi: 10.1210/endo-70-5-638. [DOI] [PubMed] [Google Scholar]
  17. CORVILAIN J., ABRAMOW M. EFFECT OF GROWTH HORMONE ON TUBULAR TRANSPORT OF PHOSPHATE IN NORMAL AND PARATHYROIDECTOMIZED DOGS. J Clin Invest. 1964 Aug;43:1608–1612. doi: 10.1172/JCI105036. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Chase L. R., Melson G. L., Aurbach G. D. Pseudohypoparathyroidism: defective excretion of 3',5'-AMP in response to parathyroid hormone. J Clin Invest. 1969 Oct;48(10):1832–1844. doi: 10.1172/JCI106149. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Coburn J. W., Massry S. G. Changes in serum and urinary calcium during phosphate depletion: studies on mechanisms. J Clin Invest. 1970 Jun;49(6):1073–1087. doi: 10.1172/JCI106323. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Coburn J. W., Popovtzer M. M., Massry S. G., Kleeman C. R. The physicochemical state and renal handling of divalent ions in chronic renal failure. Arch Intern Med. 1969 Sep;124(3):302–311. [PubMed] [Google Scholar]
  21. Cooper R. R., Milgram J. W., Robinson R. A. Morphology of the osteon. An electron microscopic study. J Bone Joint Surg Am. 1966 Oct;48(7):1239–1271. [PubMed] [Google Scholar]
  22. Copp D. H. Endocrine regulation of calcium metabolism. Annu Rev Physiol. 1970;32:61–86. doi: 10.1146/annurev.ph.32.030170.000425. [DOI] [PubMed] [Google Scholar]
  23. DENT C. E. Some problems of hyperparathyroidism. Br Med J. 1962 Dec 1;2(5317):1419–1425. doi: 10.1136/bmj.2.5317.1419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. DeLuca H. F. Recent advances in the metabolism and function of vitamin D. Fed Proc. 1969 Sep-Oct;28(5):1678–1689. [PubMed] [Google Scholar]
  25. Deftos L. J., Lee M. R., Potts J. T., Jr A radioimmunoassay for thyrocalcitonin. Proc Natl Acad Sci U S A. 1968 May;60(1):293–299. doi: 10.1073/pnas.60.1.293. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. EISENBERG E. EFFECTS OF SERUM CALCIUM LEVEL AND PARATHYROID EXTRACTS ON PHOSPHATE AND CALCIUM EXCRETION IN HYPOPARATHYROID PATIENTS. J Clin Invest. 1965 Jun;44:942–946. doi: 10.1172/JCI105211. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. ENGFELDT B., HJERTQUIST S. O., STRANDH J. R. The parathyroidal function in long term dietary experiments. Acta Endocrinol (Copenh) 1954 Feb;15(2):119–128. doi: 10.1530/acta.0.0150119. [DOI] [PubMed] [Google Scholar]
  28. Eisenberg E. Effects of varying phosphate intake in primary hyperparathyroidism. J Clin Endocrinol Metab. 1968 May;28(5):651–660. doi: 10.1210/jcem-28-5-651. [DOI] [PubMed] [Google Scholar]
  29. Estep H., Shaw W. A., Watlington C., Hobe R., Holland W., Tucker S. G. Hypocalcemia due to hypomagnesemia and reversible parathyroid hormone unresponsiveness. J Clin Endocrinol Metab. 1969 Jun;29(6):842–848. doi: 10.1210/jcem-29-6-842. [DOI] [PubMed] [Google Scholar]
  30. FOSTER G. V., MACINTYRE I., PEARSE A. G. CALCITONIN PRODUCTION AND THE MITOCHONDRION-RICH CELLS OF THE DOG THYROID. Nature. 1964 Sep 5;203:1029–1030. doi: 10.1038/2031029a0. [DOI] [PubMed] [Google Scholar]
  31. Foster G. V., Doyle F. H., Bordier P., Matrajt H. Effect of thyrocalcitonin on bone. Lancet. 1966 Dec 31;2(7479):1428–1431. doi: 10.1016/s0140-6736(66)90593-9. [DOI] [PubMed] [Google Scholar]
  32. Galante L., Gudmundsson T. V., Matthews E. W., Tse A., Williams E. D., Woodhouse N. J., MacIntyre I. Thymic and parathyroid origin of calcitonin in man. Lancet. 1968 Sep 7;2(7567):537–538. doi: 10.1016/s0140-6736(68)92408-2. [DOI] [PubMed] [Google Scholar]
  33. Gitelman H. J., Kukolj S., Welt L. G. The influence of the parathyroid glands on the hypercalcemia of experimental magnesium depletion in the rat. J Clin Invest. 1968 Jan;47(1):118–126. doi: 10.1172/JCI105702. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Gittes R. F., Radde I. C. Experimental model for hyperparathyroidism: effect of excessive numbers of transplanted isologous parathyroid glands. J Urol. 1966 May;95(5):595–603. doi: 10.1016/S0022-5347(17)63506-7. [DOI] [PubMed] [Google Scholar]
  35. Gittes R. F., Toverud S. U., Cooper C. W. Effects of hypercalcemia and hypocalcemia on the thyrocalcitonin content of rat thyroid glands. Endocrinology. 1968 Jan;82(1):83–90. doi: 10.1210/endo-82-1-83. [DOI] [PubMed] [Google Scholar]
  36. Goldsmith R. S. Effect of ions upon bone cell function. Discussion. Fed Proc. 1970 May-Jun;29(3):1198–1199. [PubMed] [Google Scholar]
  37. Goldsmith R. S., Ingbar S. H. Inorganic phosphate treatment of hypercalcemia of diverse etiologies. N Engl J Med. 1966 Jan 6;274(1):1–7. doi: 10.1056/NEJM196601062740101. [DOI] [PubMed] [Google Scholar]
  38. Gudmundsson T. V., Woodhouse N. J., Osafo T. D., Galante L., Matthews E. W., MacIntyre I., Kenny A. D., Wiggins R. C. Plasma-calcitonin in man. Lancet. 1969 Mar 1;1(7592):443–446. doi: 10.1016/s0140-6736(69)91482-2. [DOI] [PubMed] [Google Scholar]
  39. HIATT H. H., THOMPSON D. D. The effects of parathyroid extract on renal function in man. J Clin Invest. 1957 Apr;36(4):557–565. doi: 10.1172/JCI103454. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. HIRSCH P. F., GAUTHIER G. F., MUNSON P. L. THYROID HYPOCALCEMIC PRINCIPLE AND RECURRENT LARYNGEAL NERVE INJURY AS FACTORS AFFECTING THE RESPONSE TO PARATHYROIDECTOMY IN RATS. Endocrinology. 1963 Aug;73:244–252. doi: 10.1210/endo-73-2-244. [DOI] [PubMed] [Google Scholar]
  41. HIRSCH P. F., VOELKEL E. F., MUNSON P. L. THYROCALCITONIN: HYPOCALCEMIC HYPOPHOSPHATEMIC PRINCIPLE OF THE THYROID GLAND. Science. 1964 Oct 16;146(3642):412–413. doi: 10.1126/science.146.3642.412. [DOI] [PubMed] [Google Scholar]
  42. Harrison H. C., Harrison H. E. Dibutyryl cyclic AMP, vitamin D and intestinal permeability to calcium. Endocrinology. 1970 Apr;86(4):756–760. doi: 10.1210/endo-86-4-756. [DOI] [PubMed] [Google Scholar]
  43. Harrison H. E. Parathyroid hormone and vitamin D. Yale J Biol Med. 1966 Apr;38(5):393–409. [PMC free article] [PubMed] [Google Scholar]
  44. Haussler M. R., Myrtle J. F., Norman A. W. The association of a metabolite of vitamin D3 with intestinal mucosa chromatin in vivo. J Biol Chem. 1968 Aug 10;243(15):4055–4064. [PubMed] [Google Scholar]
  45. Hirsch P. F., Munson P. L. Thyrocalcitonin. Physiol Rev. 1969 Jul;49(3):548–622. doi: 10.1152/physrev.1969.49.3.548. [DOI] [PubMed] [Google Scholar]
  46. INGBAR S. H., KASS E. H., BURNETT C. H., RELMAN A. S., BURROWS B. A., SISSON J. H. The effects of ACTH and cortisone on the renal tubular transport of uric acid, phosphorus, and electrolytes in patients with normal renal and adrenal function. J Lab Clin Med. 1951 Oct;38(4):533–541. [PubMed] [Google Scholar]
  47. KLEEMAN C. R., BERNSTEIN D., ROCKNEY R., DOWLING J. T., MAXWELL M. H. Studies on the renal clearance of diffusible calcium and the role of the parathyroid glands in its regulation. Yale J Biol Med. 1961 Aug;34:1–30. [PMC free article] [PubMed] [Google Scholar]
  48. KUMAR M. A., FOSTER G. V., MACINTYRE I. FURTHER EVIDENCE FOR CALCITONIN. A RAPID-ACTING HORMONE WHICH LOWERS PLASMA-CALCIUM. Lancet. 1963 Sep 7;2(7306):480–482. doi: 10.1016/s0140-6736(63)90224-1. [DOI] [PubMed] [Google Scholar]
  49. Keating F. R., Jr The clinical problem of primary hyperparathyroidism. Med Clin North Am. 1970 Mar;54(2):511–529. [PubMed] [Google Scholar]
  50. Kennedy J. W., 3rd, Tanzer F. S., Talmage R. V. Plasma phosphate and the hypocalcemic response of intact, parathyroidectomized and nephrectomized rats to thyrocalcitonin. Endocrinology. 1969 Oct;85(4):657–661. doi: 10.1210/endo-85-4-657. [DOI] [PubMed] [Google Scholar]
  51. Klein D. C., Talmage R. V. Evidence for the secretion of thyrocalcitonin at normal and subnormal plasma calcium levels. Endocrinology. 1968 Jan;82(1):132–136. doi: 10.1210/endo-82-1-132. [DOI] [PubMed] [Google Scholar]
  52. LITVAK J., MOLDAWER M. P., FORBES A. P., HENNEMAN P. H. Hypocalcemic hypercalciuria during vitamin D and dihydrotachysterol therapy of hypoparathyroidism. J Clin Endocrinol Metab. 1958 Mar;18(3):246–252. doi: 10.1210/jcem-18-3-246. [DOI] [PubMed] [Google Scholar]
  53. Lawson D. E., Wilson P. W., Kodicek E. Metabolism of vitamin D. A new cholecalciferol metabolite, involving loss of hydrogen at C-1, in chick intestinal nuclei. Biochem J. 1969 Nov;115(2):269–277. doi: 10.1042/bj1150269. [DOI] [PMC free article] [PubMed] [Google Scholar]
  54. Lee M. R., Deftos L. J., Potts J. T., Jr Control of secretion of thyrocalcitonin in the rabbit as evaluated by radioimmunoassay. Endocrinology. 1969 Jan;84(1):36–40. doi: 10.1210/endo-84-1-36. [DOI] [PubMed] [Google Scholar]
  55. Lloyd W., Fang V. S., Wells H., Tashjian A. H., Jr 2-Thiophenecarboxylic acid: a hypoglycemic, antilipolytic agent with hypocalcemic and hypophosphatemic effects in rats. Endocrinology. 1969 Oct;85(4):763–768. doi: 10.1210/endo-85-4-763. [DOI] [PubMed] [Google Scholar]
  56. Lotz M., Zisman E., Bartter F. C. Evidence for a phosphorus-depletion syndrome in man. N Engl J Med. 1968 Feb 22;278(8):409–415. doi: 10.1056/NEJM196802222780802. [DOI] [PubMed] [Google Scholar]
  57. Massry S. G., Coburn J. W., Chapman L. W., Kleeman C. R. Role of serum Ca, parathyroid hormone, and NaCl infusion on renal Ca and Na clearances. Am J Physiol. 1968 Jun;214(6):1403–1409. doi: 10.1152/ajplegacy.1968.214.6.1403. [DOI] [PubMed] [Google Scholar]
  58. Massry S. G., Coburn J. W., Kleeman C. R. Evidence for suppression of parathyroid gland activity by hypermagnesemia. J Clin Invest. 1970 Sep;49(9):1619–1629. doi: 10.1172/JCI106379. [DOI] [PMC free article] [PubMed] [Google Scholar]
  59. Massry S. G., Coburn J. W., Kleeman C. R. Renal handling of magnesium in the dog. Am J Physiol. 1969 Jun;216(6):1460–1467. doi: 10.1152/ajplegacy.1969.216.6.1460. [DOI] [PubMed] [Google Scholar]
  60. Massry S. G., Coburn J. W., Kleeman C. R. The influence of extracellular volume expansion on renal phosphate reabsorption in the dog. J Clin Invest. 1969 Jul;48(7):1237–1245. doi: 10.1172/JCI106088. [DOI] [PMC free article] [PubMed] [Google Scholar]
  61. Massry S. G., Coburn J. W., Popovtzer M. M., Shinaberger J. H., Maxwell M. H., Kleeman C. R. Secondary hyperparathyroidism in chronic renal failure. The clinical spectrum in uremia, during hemodialysis, and after renal transplantation. Arch Intern Med. 1969 Oct;124(4):431–441. [PubMed] [Google Scholar]
  62. Massry S. G., Mueller E., Silverman A. G., Kleeman C. R. Inorganic phosphate treatment of hypercalcemia. Arch Intern Med. 1968 Apr;121(4):307–312. [PubMed] [Google Scholar]
  63. Melick R. A., Baird C. W. Changes in plasma calcium after injection of calcium in hypothyroid and hypoparathyroid women. J Clin Endocrinol Metab. 1967 Sep;27(9):1303–1308. doi: 10.1210/jcem-27-9-1303. [DOI] [PubMed] [Google Scholar]
  64. Melick R. A., Martin T. J. Parathyroid hormone metabolism in man: effect of nephrectomy. Clin Sci. 1969 Dec;37(3):667–674. [PubMed] [Google Scholar]
  65. Morii H., DeLuca H. F. Relationship between vitamin D deficiency, thyrocalcitonin, and parathyroid hormone. Am J Physiol. 1967 Aug;213(2):358–362. doi: 10.1152/ajplegacy.1967.213.2.358. [DOI] [PubMed] [Google Scholar]
  66. Myrtle J. F., Haussler M. R., Norman A. W. Evidence for the biologically active form of cholecalciferol in the intestine. J Biol Chem. 1970 Mar 10;245(5):1190–1196. [PubMed] [Google Scholar]
  67. Olson E. B., DeLuca H. F. 25-hydroxycholecalciferol: direct effect on calcium transport. Science. 1969 Jul 25;165(3891):405–407. doi: 10.1126/science.165.3891.405. [DOI] [PubMed] [Google Scholar]
  68. Parfitt A. M. Relation between parathyroid cell mass and plasma calcium concentration in normal and uremic subjects. A theoretical model with an analysis of the concept of autonomy, and speculations on the mechanism of parathyroid hyperplasia. Arch Intern Med. 1969 Sep;124(3):269–273. [PubMed] [Google Scholar]
  69. Parfitt A. M. Study of parathyroid function in man by EDTA infusion. J Clin Endocrinol Metab. 1969 Apr;29(4):569–580. doi: 10.1210/jcem-29-4-569. [DOI] [PubMed] [Google Scholar]
  70. Parsons J. A., Robinson C. J. A simplified perfusion method for study of calcium equilibrium in isolated bone. J Physiol. 1968 Feb;194(2):59–60P. [PubMed] [Google Scholar]
  71. Peacock M., Robertson W. G., Nordin B. E. Relation between serum and urinary calcium with particular reference to parathyroid activity. Lancet. 1969 Feb 22;1(7591):384–386. doi: 10.1016/s0140-6736(69)91353-1. [DOI] [PubMed] [Google Scholar]
  72. Pearse A. G., Carvalheira A. F. Cytochemical evidence for an ultimobranchial origin of rodent thyroid C cells. Nature. 1967 May 27;214(5091):929–930. doi: 10.1038/214929a0. [DOI] [PubMed] [Google Scholar]
  73. Ponchon G., Kennan A. L., DeLuca H. F. "Activation" of vitamin D by the liver. J Clin Invest. 1969 Nov;48(11):2032–2037. doi: 10.1172/JCI106168. [DOI] [PMC free article] [PubMed] [Google Scholar]
  74. Potts J. T., Jr Recent advances in thyrocalcitonin research. Fed Proc. 1970 May-Jun;29(3):1200–1205. [PubMed] [Google Scholar]
  75. Potts J. T., Reita R. E., Deftos L. J., Kaye M. B., Richardson J. A., Buckle R. M., Aurbach G. D. Secondary hyperparathyroidism in chronic renal disease. Arch Intern Med. 1969 Oct;124(4):408–412. [PubMed] [Google Scholar]
  76. RAISZ L. G. BONE RESORPTION IN TISSUE CULTURE. FACTORS INFLUENCING THE RESPONSE TO PARATHYROID HORMONE. J Clin Invest. 1965 Jan;44:103–116. doi: 10.1172/JCI105117. [DOI] [PMC free article] [PubMed] [Google Scholar]
  77. Raisz L. G., Niemann I. Effect of phosphate, calcium and magnesium on bone resorption and hormonal responses in tissue culture. Endocrinology. 1969 Sep;85(3):446–452. doi: 10.1210/endo-85-3-446. [DOI] [PubMed] [Google Scholar]
  78. Raisz L. G. Physiologic and pharmacologic regulation of bone resorption. N Engl J Med. 1970 Apr 16;282(16):909–916. doi: 10.1056/NEJM197004162821608. [DOI] [PubMed] [Google Scholar]
  79. Rasmussen H., Feinblatt J., Nagata N., Pechet M. Effect of ions upon bone cell function. Fed Proc. 1970 May-Jun;29(3):1190–1197. [PubMed] [Google Scholar]
  80. Rasmussen H., Pechet M., Fast D. Effect of dibutyryl cyclic adenosine 3',5'-monophosphate, theophylline, and other nucleotides upon calcium and phosphate metabolism. J Clin Invest. 1968 Aug;47(8):1843–1850. doi: 10.1172/JCI105874. [DOI] [PMC free article] [PubMed] [Google Scholar]
  81. Reiss E., Canterbury J. M., Kanter A. Circulating parathyroid hormone concentration in chronic renal insufficiency. Arch Intern Med. 1969 Oct;124(4):417–422. [PubMed] [Google Scholar]
  82. Rittel W., Brugger M., Kamber B., Riniker B., Sieber P. Thyrocalcitonin. 3. Die synthese des alpha-Thyrocalcitonins. Helv Chim Acta. 1968 May 31;51(4):924–928. doi: 10.1002/hlca.660510431. [DOI] [PubMed] [Google Scholar]
  83. SANDERSON P. H., MARSHALL F., 2nd, WILSON R. E. Calcium and phosphorus homeostasis in the parathyroidectomized dog; evaluation by means of ethylenediamine tetraacetate and calcium tolerance tests. J Clin Invest. 1960 Apr;39:662–670. doi: 10.1172/JCI104081. [DOI] [PMC free article] [PubMed] [Google Scholar]
  84. Sherwood L. M., Herrman I., Bassett C. A. Parathyroid hormone secretion in vitro: regulation by calcium and magnesium ions. Nature. 1970 Mar 14;225(5237):1056–1058. doi: 10.1038/2251056a0. [DOI] [PubMed] [Google Scholar]
  85. Sherwood L. M. Magnesium ion and parathyroid function. N Engl J Med. 1970 Mar 26;282(13):752–752. doi: 10.1056/NEJM197003262821315. [DOI] [PubMed] [Google Scholar]
  86. Shils M. E. Experimental human magnesium depletion. Medicine (Baltimore) 1969 Jan;48(1):61–85. doi: 10.1097/00005792-196901000-00003. [DOI] [PubMed] [Google Scholar]
  87. Stern P. H. Inhibition by steroids of parathyroid hormone-induced Ca45 release from embryonic rat bone in vitro. J Pharmacol Exp Ther. 1969 Aug;168(2):211–217. [PubMed] [Google Scholar]
  88. Sturtridge W. C., Kumar M. A. Assay of calcitonin in human plasma. Lancet. 1968 Apr 6;1(7545):725–726. doi: 10.1016/s0140-6736(68)92167-3. [DOI] [PubMed] [Google Scholar]
  89. Suki W. N., Martinez-Maldonado M., Rouse D., Terry A. Effect of expansion of extracellular fluid volume on renal phosphate handling. J Clin Invest. 1969 Oct;48(10):1888–1894. doi: 10.1172/JCI106155. [DOI] [PMC free article] [PubMed] [Google Scholar]
  90. TALMAGE R. V., KRAINTZ F. W. Progressive changes in renal phosphate and calcium excretion in rats following parathyroidectomy or parathyroid administration. Proc Soc Exp Biol Med. 1954 Nov;87(2):263–267. doi: 10.3181/00379727-87-21353. [DOI] [PubMed] [Google Scholar]
  91. THOMPSON D. D., HIATT H. H. Effects of phosphate loading and depletion on the renal excretion and reabsorption of inorganic phosphate. J Clin Invest. 1957 Apr;36(4):566–572. doi: 10.1172/JCI103455. [DOI] [PMC free article] [PubMed] [Google Scholar]
  92. Talmage R. V. A study of the effect of parathyroid hormone on bone remodeling and on calcium homeostasis. Clin Orthop Relat Res. 1967 Sep-Oct;54:163–173. [PubMed] [Google Scholar]
  93. Tashjian A. H., Jr, Voelkel E. F. Decreased thyrocalcitonin in thyroid glands from patients with hyperparathyroidism. J Clin Endocrinol Metab. 1967 Sep;27(9):1353–1357. doi: 10.1210/jcem-27-9-1353. [DOI] [PubMed] [Google Scholar]
  94. Tenenhouse A., Rasmussen H., Hawker C. D., Arnaud C. D. Thyrocalcitonin. Annu Rev Pharmacol. 1968;8:319–336. doi: 10.1146/annurev.pa.08.040168.001535. [DOI] [PubMed] [Google Scholar]
  95. Trummel C. L., Raisz L. G., Blunt J. W., Deluca H. F. 25-Hydroxycholecalciferol: stimulation of bone resorption in tissue culture. Science. 1969 Mar 28;163(3874):1450–1451. doi: 10.1126/science.163.3874.1450. [DOI] [PubMed] [Google Scholar]
  96. Vaes G. Enzymatic and other biochemical events accompanying bone resorption in tissue culture. Calcif Tissue Res. 1970;(Suppl):57–60. doi: 10.1007/BF02152351. [DOI] [PubMed] [Google Scholar]
  97. WALSER M., ROBINSON B. H., DUCKETT J. W., Jr The hypercalcemia of adrenal insufficiency. J Clin Invest. 1963 Apr;42:456–465. doi: 10.1172/JCI104734. [DOI] [PMC free article] [PubMed] [Google Scholar]
  98. WIDROW S. H., LEVINSKY N. G. The effect of parathyroid extract on renal tubular calcium reabsorption in the dog. J Clin Invest. 1962 Dec;41:2151–2159. doi: 10.1172/JCI104673. [DOI] [PMC free article] [PubMed] [Google Scholar]
  99. Wasserman R. H., Taylor A. N. Vitamin D-dependent calcium-binding protein. Response to some physiological and nutritional variables. J Biol Chem. 1968 Jul 25;243(14):3987–3993. [PubMed] [Google Scholar]
  100. Wells H., Lloyd W. Cyclic 3',5'-adenylic acid in bone and the mechanism of action of parathyroid hormone. Discussion. Fed Proc. 1970 May-Jun;29(3):1183–1184. [PubMed] [Google Scholar]

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