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. 1981 Mar 14;282(6267):849–853. doi: 10.1136/bmj.282.6267.849

Glucose turnover and metabolic and hormonal changes in ethanol-induced hypoglycaemia.

N M Wilson, P M Brown, S M Juul, S A Prestwich, P H Sönksen
PMCID: PMC1504653  PMID: 6783200

Abstract

Infusion of 67 g ethanol over four hours in fasted, non-obese normal men (a) induced hypoglycaemia by inhibiting gluconeogenesis; (b) produced noticeable increases in blood lactate, 3-hydroxybutyrate, and free fatty acid concentrations; (c) depressed plasma growth hormone concentrations, despite hypoglycaemia; and (d) raised plasma cortisol concentrations before significant hypoglycaemia occurred. These metabolic changes were explained by the reduction of redox state which accompanies ethanol oxidation. The pronounced changes in metabolic values recorded during this study suggested that the use of parenteral feeding regimens including ethanol needs to be reconsidered.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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