Skip to main content
British Medical Journal (Clinical Research Ed.) logoLink to British Medical Journal (Clinical Research Ed.)
. 1981 Jun 20;282(6281):2027–2029. doi: 10.1136/bmj.282.6281.2027

Rheumatoid arthritis and food: a case study.

A L Parke, G R Hughes
PMCID: PMC1505908  PMID: 6788180

Abstract

Clinical and laboratory studies in a patient whose rheumatoid arthritis appeared to be exacerbated by dairy produce showed that challenge with milk and cheese resulted in a produced increase in synovitis and changes in immune complexes, IgE antibodies, and heat-damaged red cell clearance rates. Exclusion of dairy products from the diet produced a considerable improvement in her previously aggressive disease.

Full text

PDF
2029

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Atherton D. J., Sewell M., Soothill J. F., Wells R. S., Chilvers C. E. A double-blind controlled crossover trial of an antigen-avoidance diet in atopic eczema. Lancet. 1978 Feb 25;1(8061):401–403. doi: 10.1016/s0140-6736(78)91199-6. [DOI] [PubMed] [Google Scholar]
  2. Brostoff J., Carini C., Wraith D. G., Johns P. Production of IgE complexes by allergen challenge in atopic patients and the effect of sodium cromoglycate. Lancet. 1979 Jun 16;1(8129):1268–1270. doi: 10.1016/s0140-6736(79)92229-3. [DOI] [PubMed] [Google Scholar]
  3. Cunningham-Rundles C., Brandeis W. E., Good R. A., Day N. K. Milk precipitins, circulating immune complexes, and IgA deficiency. Proc Natl Acad Sci U S A. 1978 Jul;75(7):3387–3389. doi: 10.1073/pnas.75.7.3387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Cunningham-Rundles C., Brandeis W. E., Safai B., O'Reilly R., Day N. K., Good R. A. Selective IgA deficiency and circulating immune complexes containing bovine proteins in a child with chronic graft versus host disease. Am J Med. 1979 Nov;67(5):883–890. doi: 10.1016/0002-9343(79)90749-6. [DOI] [PubMed] [Google Scholar]
  5. Elkon K. B., Sewell J. R., Ryan P. F., Hughes G. R. Splenic function in non-renal systemic lupus erythematosus. Am J Med. 1980 Jul;69(1):80–82. doi: 10.1016/0002-9343(80)90503-3. [DOI] [PubMed] [Google Scholar]
  6. Korenblat P. E., Rothberg R. M., Minden P., Farr R. S. Immune responses of human adults after oral and parenteral exposure to bovine serum albumin. J Allergy. 1968 Apr;41(4):226–235. doi: 10.1016/0021-8707(68)90046-4. [DOI] [PubMed] [Google Scholar]
  7. Kraehenbuhl J. P., Campiche M. A. Early stages of intestinal absorption of specific antibiodies in the newborn. An ultrastructural, cytochemical, and immunological study in the pig, rat, and rabbit. J Cell Biol. 1969 Aug;42(2):345–365. doi: 10.1083/jcb.42.2.345. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Lessof M. H., Wraith D. G., Merrett T. G., Merrett J., Buisseret P. D. Food allergy and intolerance in 100 patients---local and systemic effects. Q J Med. 1980;49(195):259–271. [PubMed] [Google Scholar]
  9. Matthew D. J., Taylor B., Norman A. P., Turner M. W. Prevention of eczema. Lancet. 1977 Feb 12;1(8007):321–324. doi: 10.1016/s0140-6736(77)91131-x. [DOI] [PubMed] [Google Scholar]
  10. Paganelli R., Levinsky R. J., Brostoff J., Wraith D. G. Immune complexes containing food proteins in normal and atopic subjects after oral challenge and effect of sodium cromoglycate on antigen absorption. Lancet. 1979 Jun 16;1(8129):1270–1272. doi: 10.1016/s0140-6736(79)92230-x. [DOI] [PubMed] [Google Scholar]
  11. Ritchie D. M., Boyle J. A., McInnes J. M., Jasani M. K., Dalakos T. G., Grieveson P., Buchanan W. W. Clinical studies with an articular index for the assessment of joint tenderness in patients with rheumatoid arthritis. Q J Med. 1968 Jul;37(147):393–406. [PubMed] [Google Scholar]
  12. Walker W. A., Isselbacher K. J. Uptake and transport of macromolecules by the intestine. Possible role in clinical disorders. Gastroenterology. 1974 Sep;67(3):531–550. [PubMed] [Google Scholar]
  13. Wide L., Bennich H., Johansson S. G. Diagnosis of allergy by an in-vitro test for allergen antibodies. Lancet. 1967 Nov 25;2(7526):1105–1107. doi: 10.1016/s0140-6736(67)90615-0. [DOI] [PubMed] [Google Scholar]
  14. Zubler R. H., Lange G., Lambert P. H., Miescher P. A. Detection of immune complexes in unheated sera by modified 125I-Clq binding test. Effect of heating on the binding of Clq by immune complexes and application of the test to systemic lupus erythematosus. J Immunol. 1976 Jan;116(1):232–235. [PubMed] [Google Scholar]

Articles from British Medical Journal (Clinical research ed.) are provided here courtesy of BMJ Publishing Group

RESOURCES