Abstract
OBJECTIVES: The effect of caffeine consumption on fertility was examined prospectively in 210 women. METHODS: Women reported on caffeinated beverage consumption and pregnancy status monthly. Odds ratios for becoming pregnant were calculated for both high and moderate vs low consumption. RESULTS: No significant association was found for any of the caffeinated beverages except tea. Drinking one-half cup or more of tea daily approximately doubled the odds of conception per cycle. CONCLUSIONS: These data suggest that caffeine may not be the responsible agent for variation in fertility associated with consumption of the beverages examined.
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Selected References
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- Alderete E., Eskenazi B., Sholtz R. Effect of cigarette smoking and coffee drinking on time to conception. Epidemiology. 1995 Jul;6(4):403–408. doi: 10.1097/00001648-199507000-00013. [DOI] [PubMed] [Google Scholar]
- Baird D. D., Wilcox A. J., Weinberg C. R. Use of time to pregnancy to study environmental exposures. Am J Epidemiol. 1986 Sep;124(3):470–480. doi: 10.1093/oxfordjournals.aje.a114417. [DOI] [PubMed] [Google Scholar]
- Blakeslee J. A., Wilson H. R. Response of hens to various dietary levels of tannic acid. Poult Sci. 1979 Jan;58(1):255–256. doi: 10.3382/ps.0580255. [DOI] [PubMed] [Google Scholar]
- Block G., Woods M., Potosky A., Clifford C. Validation of a self-administered diet history questionnaire using multiple diet records. J Clin Epidemiol. 1990;43(12):1327–1335. doi: 10.1016/0895-4356(90)90099-b. [DOI] [PubMed] [Google Scholar]
- Bunker M. L., McWilliams M. Caffeine content of common beverages. J Am Diet Assoc. 1979 Jan;74(1):28–32. [PubMed] [Google Scholar]
- Christianson R. E., Oechsli F. W., van den Berg B. J. Caffeinated beverages and decreased fertility. Lancet. 1989 Feb 18;1(8634):378–378. doi: 10.1016/s0140-6736(89)91745-5. [DOI] [PubMed] [Google Scholar]
- Florack E. I., Zielhuis G. A., Rolland R. Cigarette smoking, alcohol consumption, and caffeine intake and fecundability. Prev Med. 1994 Mar;23(2):175–180. doi: 10.1006/pmed.1994.1024. [DOI] [PubMed] [Google Scholar]
- Grodstein F., Goldman M. B., Ryan L., Cramer D. W. Relation of female infertility to consumption of caffeinated beverages. Am J Epidemiol. 1993 Jun 15;137(12):1353–1360. doi: 10.1093/oxfordjournals.aje.a116644. [DOI] [PubMed] [Google Scholar]
- Joesoef M. R., Beral V., Rolfs R. T., Aral S. O., Cramer D. W. Are caffeinated beverages risk factors for delayed conception? Lancet. 1990 Jan 20;335(8682):136–137. doi: 10.1016/0140-6736(90)90005-p. [DOI] [PubMed] [Google Scholar]
- Olsen J. Cigarette smoking, tea and coffee drinking, and subfecundity. Am J Epidemiol. 1991 Apr 1;133(7):734–739. doi: 10.1093/oxfordjournals.aje.a115948. [DOI] [PubMed] [Google Scholar]
- Peaslee M. H., Einhellig F. A. Reduced fecundity in mice on tannic acid diet. Comp Gen Pharmacol. 1973 Dec;4(16):393–397. doi: 10.1016/0010-4035(73)90050-5. [DOI] [PubMed] [Google Scholar]
- Schwarz B., Bischof H. P., Kunze M. Coffee, tea, and lifestyle. Prev Med. 1994 May;23(3):377–384. doi: 10.1006/pmed.1994.1052. [DOI] [PubMed] [Google Scholar]
- Stanton C. K., Gray R. H. Effects of caffeine consumption on delayed conception. Am J Epidemiol. 1995 Dec 15;142(12):1322–1329. doi: 10.1093/oxfordjournals.aje.a117600. [DOI] [PubMed] [Google Scholar]
- Wilcox A. J., Weinberg C. R. Tea and fertility. Lancet. 1991 May 11;337(8750):1159–1160. doi: 10.1016/0140-6736(91)92825-m. [DOI] [PubMed] [Google Scholar]
- Wilcox A., Weinberg C., Baird D. Caffeinated beverages and decreased fertility. Lancet. 1988 Dec 24;2(8626-8627):1453–1456. doi: 10.1016/s0140-6736(88)90933-6. [DOI] [PubMed] [Google Scholar]
- Williams M. A., Monson R. R., Goldman M. B., Mittendorf R., Ryan K. J. Coffee and delayed conception. Lancet. 1990 Jun 30;335(8705):1603–1603. doi: 10.1016/0140-6736(90)91440-l. [DOI] [PubMed] [Google Scholar]
- Yang C. S., Wang Z. Y. Tea and cancer. J Natl Cancer Inst. 1993 Jul 7;85(13):1038–1049. doi: 10.1093/jnci/85.13.1038. [DOI] [PubMed] [Google Scholar]