Skip to main content
PMC home page
American Journal of Public Health logoLink to American Journal of Public Health
. 1999 Jan;89(1):81–84. doi: 10.2105/ajph.89.1.81

Peptic ulcer disease and exposure to domestic pets.

W J McIsaac 1, G M Leung 1
PMCID: PMC1508494  PMID: 9987471

Abstract

OBJECTIVES: This study assessed whether an association exists between household pets and peptic ulcer disease. METHODS: Canadian adults (n = 15,779) were asked about cats or dogs in their household and about history of peptic ulcer disease. Logistic regression was used to assess the association between pet ownership and a history of peptic ulcer disease, after adjustment for sociodemographic differences. RESULTS: No relationship was observed between report of household pets and a history of peptic ulcer disease (adjusted odds ratio = 1.14, 95% confidence interval = 0.95, 1.36). CONCLUSIONS: In a large sample of Canadian adults, no association was observed between pet ownership and a history of peptic ulcer disease.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Blecker U., Lanciers S., Hauser B., Vandenplas Y. The prevalence of Helicobacter pylori positivity in a symptom-free population, aged 1 to 40 years. J Clin Epidemiol. 1994 Oct;47(10):1095–1098. doi: 10.1016/0895-4356(94)90095-7. [DOI] [PubMed] [Google Scholar]
  2. Bourke B., Jones N., Sherman P. Helicobacter pylori infection and peptic ulcer disease in children. Pediatr Infect Dis J. 1996 Jan;15(1):1–13. doi: 10.1097/00006454-199601000-00002. [DOI] [PubMed] [Google Scholar]
  3. Bronsdon M. A., Schoenknecht F. D. Campylobacter pylori isolated from the stomach of the monkey, Macaca nemestrina. J Clin Microbiol. 1988 Sep;26(9):1725–1728. doi: 10.1128/jcm.26.9.1725-1728.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Chodos J. E., Dworkin B. M., Smith F., Van Horn K., Weiss L., Rosenthal W. S. Campylobacter pylori and gastroduodenal disease: a prospective endoscopic study and comparison of diagnostic tests. Am J Gastroenterol. 1988 Nov;83(11):1226–1230. [PubMed] [Google Scholar]
  5. Drazek E. S., Dubois A., Holmes R. K. Characterization and presumptive identification of Helicobacter pylori isolates from rhesus monkeys. J Clin Microbiol. 1994 Jul;32(7):1799–1804. doi: 10.1128/jcm.32.7.1799-1804.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Drumm B., Sherman P., Cutz E., Karmali M. Association of Campylobacter pylori on the gastric mucosa with antral gastritis in children. N Engl J Med. 1987 Jun 18;316(25):1557–1561. doi: 10.1056/NEJM198706183162501. [DOI] [PubMed] [Google Scholar]
  7. Fiedorek S. C., Malaty H. M., Evans D. L., Pumphrey C. L., Casteel H. B., Evans D. J., Jr, Graham D. Y. Factors influencing the epidemiology of Helicobacter pylori infection in children. Pediatrics. 1991 Sep;88(3):578–582. [PubMed] [Google Scholar]
  8. Fox J. G., Batchelder M., Marini R., Yan L., Handt L., Li X., Shames B., Hayward A., Campbell J., Murphy J. C. Helicobacter pylori-induced gastritis in the domestic cat. Infect Immun. 1995 Jul;63(7):2674–2681. doi: 10.1128/iai.63.7.2674-2681.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Fox J. G. Non-human reservoirs of Helicobacter pylori. Aliment Pharmacol Ther. 1995;9 (Suppl 2):93–103. [PubMed] [Google Scholar]
  10. Goodman K. J., Correa P., Tenganá Aux H. J., Ramírez H., DeLany J. P., Guerrero Pepinosa O., López Quiñones M., Collazos Parra T. Helicobacter pylori infection in the Colombian Andes: a population-based study of transmission pathways. Am J Epidemiol. 1996 Aug 1;144(3):290–299. doi: 10.1093/oxfordjournals.aje.a008924. [DOI] [PubMed] [Google Scholar]
  11. Goodman K. J., Correa P. The transmission of Helicobacter pylori. A critical review of the evidence. Int J Epidemiol. 1995 Oct;24(5):875–887. doi: 10.1093/ije/24.5.875. [DOI] [PubMed] [Google Scholar]
  12. Goodwin C. S., Mendall M. M., Northfield T. C. Helicobacter pylori infection. Lancet. 1997 Jan 25;349(9047):265–269. doi: 10.1016/S0140-6736(96)07023-7. [DOI] [PubMed] [Google Scholar]
  13. Graham D. Y., Malaty H. M., Evans D. G., Evans D. J., Jr, Klein P. D., Adam E. Epidemiology of Helicobacter pylori in an asymptomatic population in the United States. Effect of age, race, and socioeconomic status. Gastroenterology. 1991 Jun;100(6):1495–1501. doi: 10.1016/0016-5085(91)90644-z. [DOI] [PubMed] [Google Scholar]
  14. Handt L. K., Fox J. G., Dewhirst F. E., Fraser G. J., Paster B. J., Yan L. L., Rozmiarek H., Rufo R., Stalis I. H. Helicobacter pylori isolated from the domestic cat: public health implications. Infect Immun. 1994 Jun;62(6):2367–2374. doi: 10.1128/iai.62.6.2367-2374.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Jones D. M., Lessells A. M., Eldridge J. Campylobacter like organisms on the gastric mucosa: culture, histological, and serological studies. J Clin Pathol. 1984 Sep;37(9):1002–1006. doi: 10.1136/jcp.37.9.1002. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Kilbridge P. M., Dahms B. B., Czinn S. J. Campylobacter pylori--associated gastritis and peptic ulcer disease in children. Am J Dis Child. 1988 Nov;142(11):1149–1152. doi: 10.1001/archpedi.1988.02150110027012. [DOI] [PubMed] [Google Scholar]
  17. Lavelle J. P., Landas S., Mitros F. A., Conklin J. L. Acute gastritis associated with spiral organisms from cats. Dig Dis Sci. 1994 Apr;39(4):744–750. doi: 10.1007/BF02087417. [DOI] [PubMed] [Google Scholar]
  18. Lee A., Fox J. G., Otto G., Murphy J. A small animal model of human Helicobacter pylori active chronic gastritis. Gastroenterology. 1990 Nov;99(5):1315–1323. doi: 10.1016/0016-5085(90)91156-z. [DOI] [PubMed] [Google Scholar]
  19. Mendall M. A., Goggin P. M., Molineaux N., Levy J., Toosy T., Strachan D., Northfield T. C. Childhood living conditions and Helicobacter pylori seropositivity in adult life. Lancet. 1992 Apr 11;339(8798):896–897. doi: 10.1016/0140-6736(92)90931-r. [DOI] [PubMed] [Google Scholar]
  20. Mendall M. A., Northfield T. C. Transmission of Helicobacter pylori infection. Gut. 1995 Jul;37(1):1–3. doi: 10.1136/gut.37.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Mégraud F. Epidemiology of Helicobacter pylori infection. Gastroenterol Clin North Am. 1993 Mar;22(1):73–88. [PubMed] [Google Scholar]
  22. Newell D. G., Hudson M. J., Baskerville A. Isolation of a gastric campylobacter-like organism from the stomach of four rhesus monkeys, and identification as Campylobacter pylori. J Med Microbiol. 1988 Sep;27(1):41–44. doi: 10.1099/00222615-27-1-41. [DOI] [PubMed] [Google Scholar]
  23. Otto G., Hazell S. H., Fox J. G., Howlett C. R., Murphy J. C., O'Rourke J. L., Lee A. Animal and public health implications of gastric colonization of cats by Helicobacter-like organisms. J Clin Microbiol. 1994 Apr;32(4):1043–1049. doi: 10.1128/jcm.32.4.1043-1049.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Sahay P., Axon A. T. Reservoirs of Helicobacter pylori and modes of transmission. Helicobacter. 1996 Sep;1(3):175–182. doi: 10.1111/j.1523-5378.1996.tb00035.x. [DOI] [PubMed] [Google Scholar]
  26. Stolte M., Wellens E., Bethke B., Ritter M., Eidt H. Helicobacter heilmannii (formerly Gastrospirillum hominis) gastritis: an infection transmitted by animals? Scand J Gastroenterol. 1994 Dec;29(12):1061–1064. doi: 10.3109/00365529409094888. [DOI] [PubMed] [Google Scholar]
  27. Taylor D. N., Blaser M. J. The epidemiology of Helicobacter pylori infection. Epidemiol Rev. 1991;13:42–59. doi: 10.1093/oxfordjournals.epirev.a036078. [DOI] [PubMed] [Google Scholar]
  28. Webb P. M., Knight T., Greaves S., Wilson A., Newell D. G., Elder J., Forman D. Relation between infection with Helicobacter pylori and living conditions in childhood: evidence for person to person transmission in early life. BMJ. 1994 Mar 19;308(6931):750–753. doi: 10.1136/bmj.308.6931.750. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Wegmann W., Aschwanden M., Schaub N., Aenishänslin W., Gyr K. Gastrospirillum-hominis-assoziierte Gastritis--eine Zoonose? Schweiz Med Wochenschr. 1991 Feb 23;121(8):245–254. [PubMed] [Google Scholar]
  30. Zhou D., Yang H. Epidemiology of Helicobacter pylori infection in the People's Republic of China. Chin Med J (Engl) 1995 Apr;108(4):304–313. [PubMed] [Google Scholar]

Articles from American Journal of Public Health are provided here courtesy of American Public Health Association

RESOURCES