Skip to main content

. 1954 Mar;9(1):1–14. doi: 10.1111/j.1476-5381.1954.tb00809.x

Investigation of the toxicity of a series of dextran sulphates of varying molecular weight

Kenneth W Walton

PMCID: PMC1509383 PMID: 13149769

Images in this article

FIG. 10
on p.8-2

FIG. 11
on p.8-2

FIG. 12
on p.8-2

FIG. 13
on p.8-2

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

ASTRUP T. The toxicity of synthetic heparin substitutes. Scand J Clin Lab Invest. 1953;5(2):137–142. [PubMed] [Google Scholar]
COONS A. H., LEDUC E. H., KAPLAN M. H. Localization of antigen in tissue cells. VI. The fate of injected foreign proteins in the mouse. J Exp Med. 1951 Feb;93(2):173–188. doi: 10.1084/jem.93.2.173. [DOI] [PMC free article] [PubMed] [Google Scholar]
DUFF I. F., LINMAN J. W., BIRCH R. The administration of heparin. Surg Gynecol Obstet. 1951 Sep;93(3):343–362. [PubMed] [Google Scholar]
FLETCHER F., MARTIN L. E., RATCLIFFE A. H. Interaction of macromolecules and fibrinogen. Nature. 1952 Aug 23;170(4321):319–319. doi: 10.1038/170319a0. [DOI] [PubMed] [Google Scholar]
GOOD R. A., THOMAS L. Studies on the generalized Shwartzman reaction. II. The production of bilateral cortical necrosis of the kidneys by a single injection of bacterial toxin in rabbits previously treated with thorotrast or trypan blue. J Exp Med. 1952 Dec;96(6):625–641. doi: 10.1084/jem.96.6.625. [DOI] [PMC free article] [PubMed] [Google Scholar]
Hueper W. C. Experimental Studies in Cardiovascular Pathology: V. Effects of Intravenous Injections of Solutions of Gum Arabic, Egg Albumin and Gelatin upon the Blood and Organs of Dogs and Rabbits. Am J Pathol. 1942 Sep;18(5):895–933. [PMC free article] [PubMed] [Google Scholar]
KAPLAN M. E., COONS A. H., DEANE H. W. Localization of antigen in tissue cells; cellular distribution of pneumococcal polysaccharides types II and III in the mouse. J Exp Med. 1950 Jan 1;91(1):15-30, 4 pl. doi: 10.1084/jem.91.1.15. [DOI] [PMC free article] [PubMed] [Google Scholar]
MCDEVITT E., HUEBNER R. D., WRIGHT I. S. Ineffectiveness of heparin by sublingual administration. J Am Med Assoc. 1952 Mar 29;148(13):1123–1124. doi: 10.1001/jama.1952.62930130003013a. [DOI] [PubMed] [Google Scholar]
RICKETTS C. R. Dextran sulphate--a synthetic analogue of heparin. Biochem J. 1952 Apr;51(1):129–133. doi: 10.1042/bj0510129. [DOI] [PMC free article] [PubMed] [Google Scholar]
RICKETTS C. R., WALTON K. W. Dextran sulphate: the relation of molecular features to biological properties. Br J Pharmacol Chemother. 1953 Dec;8(4):476–477. doi: 10.1111/j.1476-5381.1953.tb01351.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
RICKETTS C. R., WALTON K. W., VAN LEUVEN B. D., BIRBECK A., BROWN A., KENNEDY A. C., BURT C. C. Therapeutic trial of the synthetic heparin analogue dextran sulphate. Lancet. 1953 Nov 14;265(6794):1004–1010. doi: 10.1016/s0140-6736(53)91306-3. [DOI] [PubMed] [Google Scholar]
STETSON C. A., GOOD R. A. Studies on the mechanism of the Shwartzman-phenomenon; evidence for the participation of polymorphonuclear leucocytes in the phenomenon. J Exp Med. 1951 Jan;93(1):49–63. doi: 10.1084/jem.93.1.49. [DOI] [PMC free article] [PubMed] [Google Scholar]
THOMAS L., DENNY F. W., Jr, FLOYD J. Studies on the generalized Shwartzman reaction. III. Lesions of the myocardium and coronary arteries accompanying the reaction in rabbits prepared by infection with group A streptococci. J Exp Med. 1953 May;97(5):751–766. doi: 10.1084/jem.97.5.751. [DOI] [PMC free article] [PubMed] [Google Scholar]
THOMAS L., GOOD R. A. Studies on the generalized Shwartzman reaction: I. General observations concerning the phenomenon. J Exp Med. 1952 Dec;96(6):605–624. doi: 10.1084/jem.96.6.605. [DOI] [PMC free article] [PubMed] [Google Scholar]
WALTON K. Experiments with dextran sulphate as an anticoagulant. Proc R Soc Med. 1951 Jul;44(7):563–564. [PMC free article] [PubMed] [Google Scholar]

ACTIONS

RESOURCES