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. 1995 Sep;73(3):216–220. doi: 10.1136/adc.73.3.216

The effect of iron in formula milk after 6 months of age.

D Stevens 1, A Nelson 1
PMCID: PMC1511272  PMID: 7492158

Abstract

Ninety two normal birthweight infants aged 6 months entered a double blind controlled trial which compared a follow on formula milk with no added iron against the same formula milk containing 1.2 mg of iron per 100 ml. There was no significant difference in the social class or demographic characteristics of the two treatment groups or in the proportion of each group completing the trial. There was no difference between the two groups in the quantity of milk taken but the amounts taken lessened between 6 and 18 months of age. There was no difference between the two groups with respect to mean haemoglobin and median serum ferritin at 6, 9, 12, 15, and 18 months of age. Very few infants developed iron deficiency anaemia in either group but there was a tendency for serum ferritin levels to fall between 6 and 18 months of age in both groups. The results suggest that iron added to follow on milk was not an important source of dietary iron in the infants studied.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Addy D. P. Happiness is: iron. Br Med J (Clin Res Ed) 1986 Apr 12;292(6526):969–970. doi: 10.1136/bmj.292.6526.969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Aukett M. A., Parks Y. A., Scott P. H., Wharton B. A. Treatment with iron increases weight gain and psychomotor development. Arch Dis Child. 1986 Sep;61(9):849–857. doi: 10.1136/adc.61.9.849. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bradley C. K., Hillman L., Sherman A. R., Leedy D., Cordano A. Evaluation of two iron-fortified, milk-based formulas during infancy. Pediatrics. 1993 May;91(5):908–914. [PubMed] [Google Scholar]
  4. Dallman P. R., Yip R. Changing characteristics of childhood anemia. J Pediatr. 1989 Jan;114(1):161–164. doi: 10.1016/s0022-3476(89)80625-0. [DOI] [PubMed] [Google Scholar]
  5. Dawson D. W., Fish D. I., Shackleton P. The accuracy and clinical interpretation of serum ferritin assays. Clin Lab Haematol. 1992;14(1):47–52. [PubMed] [Google Scholar]
  6. Elin R. J., Wolff S. M., Finch C. A. Effect of induced fever on serum iron and ferritin concentrations in man. Blood. 1977 Jan;49(1):147–153. [PubMed] [Google Scholar]
  7. Haschke F., Vanura H., Male C., Owen G., Pietschnig B., Schuster E., Krobath E., Huemer C. Iron nutrition and growth of breast- and formula-fed infants during the first 9 months of life. J Pediatr Gastroenterol Nutr. 1993 Feb;16(2):151–156. doi: 10.1097/00005176-199302000-00009. [DOI] [PubMed] [Google Scholar]
  8. Jansson L. T., Kling S., Dallman P. R. Anemia in children with acute infections seen in a primary care pediatric outpatient clinic. Pediatr Infect Dis. 1986 Jul-Aug;5(4):424–427. doi: 10.1097/00006454-198607000-00009. [DOI] [PubMed] [Google Scholar]
  9. McMillan J. A., Oski F. A., Lourie G., Tomarelli R. M., Landaw S. A. Iron absorption from human milk, simulated human milk, and proprietary formulas. Pediatrics. 1977 Dec;60(6):896–900. [PubMed] [Google Scholar]
  10. Oski F. A. Iron deficiency in infancy and childhood. N Engl J Med. 1993 Jul 15;329(3):190–193. doi: 10.1056/NEJM199307153290308. [DOI] [PubMed] [Google Scholar]
  11. Owen G. M., Lubin A. H., Garry P. J. Preschool children in the United States: who has iron deficiency? J Pediatr. 1971 Oct;79(4):563–568. doi: 10.1016/s0022-3476(71)80301-3. [DOI] [PubMed] [Google Scholar]
  12. Stevens D. Epidemiology of hypochromic anaemia in young children. Arch Dis Child. 1991 Jul;66(7):886–889. doi: 10.1136/adc.66.7.886. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Walter T., Dallman P. R., Pizarro F., Velozo L., Peña G., Bartholmey S. J., Hertrampf E., Olivares M., Letelier A., Arredondo M. Effectiveness of iron-fortified infant cereal in prevention of iron deficiency anemia. Pediatrics. 1993 May;91(5):976–982. [PubMed] [Google Scholar]

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