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. 1993 Dec;101(Suppl 6):111–114. doi: 10.1289/ehp.93101s6111

Renal cell cancer and exposure to gasoline: a review.

J K McLaughlin 1
PMCID: PMC1520003  PMID: 8020434

Abstract

A review of the epidemiology of renal cell cancer is presented. Risk factors for renal cell cancer such as cigarette smoking, obesity, diet, and use of analgesics and prescription diuretics are examined. Although uncommon, occupational risk factors are also reviewed. Studies examining gasoline exposure and renal cell cancer are evaluated, including investigations recently presented at a meeting on this topic. Overall, most studies find no link between gasoline exposure and renal cell cancer; moreover, the experimental evidence that initiated the health concern is no longer considered relevant to humans. Positive associations, however, reported in two recent studies prevent a firm conclusion of no risk for this exposure.

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Selected References

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  1. Asal N. R., Geyer J. R., Risser D. R., Lee E. T., Kadamani S., Cherng N. Risk factors in renal cell carcinoma. II. Medical history, occupation, multivariate analysis, and conclusions. Cancer Detect Prev. 1988;13(3-4):263–279. [PubMed] [Google Scholar]
  2. Bertrand P., Girard N., Delpech B., Duval C., d'Anjou J., Dauce J. P. Hyaluronan (hyaluronic acid) and hyaluronectin in the extracellular matrix of human breast carcinomas: comparison between invasive and non-invasive areas. Int J Cancer. 1992 Aug 19;52(1):1–6. doi: 10.1002/ijc.2910520102. [DOI] [PubMed] [Google Scholar]
  3. Blair A., Decoufle P., Grauman D. Causes of death among laundry and dry cleaning workers. Am J Public Health. 1979 May;69(5):508–511. doi: 10.2105/ajph.69.5.508. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Blair A., Stewart P. A., Tolbert P. E., Grauman D., Moran F. X., Vaught J., Rayner J. Cancer and other causes of death among a cohort of dry cleaners. Br J Ind Med. 1990 Mar;47(3):162–168. doi: 10.1136/oem.47.3.162. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Brown D. P., Kaplan S. D. Retrospective cohort mortality study of dry cleaner workers using perchloroethylene. J Occup Med. 1987 Jun;29(6):535–541. [PubMed] [Google Scholar]
  6. Brownson R. C. A case-control study of renal cell carcinoma in relation to occupation, smoking, and alcohol consumption. Arch Environ Health. 1988 May-Jun;43(3):238–241. doi: 10.1080/00039896.1988.9934940. [DOI] [PubMed] [Google Scholar]
  7. Devesa S. S., Silverman D. T., McLaughlin J. K., Brown C. C., Connelly R. R., Fraumeni J. F., Jr Comparison of the descriptive epidemiology of urinary tract cancers. Cancer Causes Control. 1990 Sep;1(2):133–141. doi: 10.1007/BF00053164. [DOI] [PubMed] [Google Scholar]
  8. Domiano S. F., Vena J. E., Swanson M. K. Gasoline exposure, smoking, and kidney cancer. J Occup Med. 1985 Jun;27(6):398–399. [PubMed] [Google Scholar]
  9. Duh R. W., Asal N. R. Mortality among laundry and dry cleaning workers in Oklahoma. Am J Public Health. 1984 Nov;74(11):1278–1280. doi: 10.2105/ajph.74.11.1278. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Enterline P. E., Hartley J., Henderson V. Asbestos and cancer: a cohort followed up to death. Br J Ind Med. 1987 Jun;44(6):396–401. doi: 10.1136/oem.44.6.396. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Fraser G. E., Phillips R. L., Beeson W. L. Hypertension, antihypertensive medication and risk of renal carcinoma in California Seventh-Day Adventists. Int J Epidemiol. 1990 Dec;19(4):832–838. doi: 10.1093/ije/19.4.832. [DOI] [PubMed] [Google Scholar]
  12. Grove J. S., Nomura A., Severson R. K., Stemmermann G. N. The association of blood pressure with cancer incidence in a prospective study. Am J Epidemiol. 1991 Nov 1;134(9):942–947. doi: 10.1093/oxfordjournals.aje.a116178. [DOI] [PubMed] [Google Scholar]
  13. Katz R. M., Jowett D. Female laundry and dry cleaning workers in Wisconsin: a mortality analysis. Am J Public Health. 1981 Mar;71(3):305–307. doi: 10.2105/ajph.71.3.305. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Kolonel L. N. Association of cadmium with renal cancer. Cancer. 1976 Apr;37(4):1782–1787. doi: 10.1002/1097-0142(197604)37:4<1782::aid-cncr2820370424>3.0.co;2-f. [DOI] [PubMed] [Google Scholar]
  15. Maclure M. Asbestos and renal adenocarcinoma: a case-control study. Environ Res. 1987 Apr;42(2):353–361. doi: 10.1016/s0013-9351(87)80200-1. [DOI] [PubMed] [Google Scholar]
  16. Maclure M., Willett W. A case-control study of diet and risk of renal adenocarcinoma. Epidemiology. 1990 Nov;1(6):430–440. doi: 10.1097/00001648-199011000-00004. [DOI] [PubMed] [Google Scholar]
  17. McCredie M., Ford J. M., Stewart J. H. Risk factors for cancer of the renal parenchyma. Int J Cancer. 1988 Jul 15;42(1):13–16. doi: 10.1002/ijc.2910420104. [DOI] [PubMed] [Google Scholar]
  18. McLaughlin J. K., Blot W. J., Fraumeni J. F., Jr Diuretics and renal cell cancer. J Natl Cancer Inst. 1988 May 4;80(5):378–378. doi: 10.1093/jnci/80.5.378. [DOI] [PubMed] [Google Scholar]
  19. McLaughlin J. K., Blot W. J., Mehl E. S., Stewart P. A., Venable F. S., Fraumeni J. F., Jr Petroleum-related employment and renal cell cancer. J Occup Med. 1985 Sep;27(9):672–674. [PubMed] [Google Scholar]
  20. McLaughlin J. K., Hrubec Z., Heineman E. F., Blot W. J., Fraumeni J. F., Jr Renal cancer and cigarette smoking in a 26-year followup of U.S. veterans. Public Health Rep. 1990 Sep-Oct;105(5):535–537. [PMC free article] [PubMed] [Google Scholar]
  21. McLaughlin J. K., Mandel J. S., Blot W. J., Schuman L. M., Mehl E. S., Fraumeni J. F., Jr A population--based case--control study of renal cell carcinoma. J Natl Cancer Inst. 1984 Feb;72(2):275–284. [PubMed] [Google Scholar]
  22. Paganini-Hill A., Glazer E., Henderson B. E., Ross R. K. Cause-specific mortality among newspaper web pressmen. J Occup Med. 1980 Aug;22(8):542–544. doi: 10.1097/00043764-198008000-00011. [DOI] [PubMed] [Google Scholar]
  23. Partanen T., Heikkilä P., Hernberg S., Kauppinen T., Moneta G., Ojajärvi A. Renal cell cancer and occupational exposure to chemical agents. Scand J Work Environ Health. 1991 Aug;17(4):231–239. doi: 10.5271/sjweh.1708. [DOI] [PubMed] [Google Scholar]
  24. Redmond C. K., Ciocco A., Lloyd J. W., Rush H. W. Long-term mortality study of steelworkers. VI. Mortality from malignant neoplasms among coke oven workers. J Occup Med. 1972 Aug;14(8):621–629. [PubMed] [Google Scholar]
  25. Rushton L. A 39-year follow-up of the U.K. oil refinery and distribution center studies: results for kidney cancer and leukemia. Environ Health Perspect. 1993 Dec;101 (Suppl 6):77–84. doi: 10.1289/ehp.93101s677. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Selikoff I. J., Hammond E. C., Seidman H. Mortality experience of insulation workers in the United States and Canada, 1943--1976. Ann N Y Acad Sci. 1979;330:91–116. doi: 10.1111/j.1749-6632.1979.tb18711.x. [DOI] [PubMed] [Google Scholar]
  27. Shalat S. L., True L. D., Fleming L. E., Pace P. E. Kidney cancer in utility workers exposed to polychlorinated biphenyls (PCBs) Br J Ind Med. 1989 Nov;46(11):823–824. doi: 10.1136/oem.46.11.823. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Siemiatycki J., Dewar R., Nadon L., Gérin M., Richardson L., Wacholder S. Associations between several sites of cancer and twelve petroleum-derived liquids. Results from a case-referent study in Montreal. Scand J Work Environ Health. 1987 Dec;13(6):493–504. doi: 10.5271/sjweh.2008. [DOI] [PubMed] [Google Scholar]
  29. Spirtas R., Stewart P. A., Lee J. S., Marano D. E., Forbes C. D., Grauman D. J., Pettigrew H. M., Blair A., Hoover R. N., Cohen J. L. Retrospective cohort mortality study of workers at an aircraft maintenance facility. I. Epidemiological results. Br J Ind Med. 1991 Aug;48(8):515–530. doi: 10.1136/oem.48.8.515. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Talamini R., Barón A. E., Barra S., Bidoli E., La Vecchia C., Negri E., Serraino D., Franceschi S. A case-control study of risk factor for renal cell cancer in northern Italy. Cancer Causes Control. 1990 Sep;1(2):125–131. doi: 10.1007/BF00053163. [DOI] [PubMed] [Google Scholar]
  31. Tu J. T., Gao R. N., Zhang D. H., Gu B. C. Hepatitis B virus and primary liver cancer on Chongming Island, People's Republic of China. Natl Cancer Inst Monogr. 1985 Dec;69:213–215. [PubMed] [Google Scholar]
  32. Wacholder S., McLaughlin J. K., Silverman D. T., Mandel J. S. Selection of controls in case-control studies. I. Principles. Am J Epidemiol. 1992 May 1;135(9):1019–1028. doi: 10.1093/oxfordjournals.aje.a116396. [DOI] [PubMed] [Google Scholar]
  33. Wong O., Raabe G. K. Critical review of cancer epidemiology in petroleum industry employees, with a quantitative meta-analysis by cancer site. Am J Ind Med. 1989;15(3):283–310. doi: 10.1002/ajim.4700150305. [DOI] [PubMed] [Google Scholar]
  34. Yu M. C., Mack T. M., Hanisch R., Cicioni C., Henderson B. E. Cigarette smoking, obesity, diuretic use, and coffee consumption as risk factors for renal cell carcinoma. J Natl Cancer Inst. 1986 Aug;77(2):351–356. [PubMed] [Google Scholar]

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