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. 1983 Sep;53(3):659–662.

The immune system in familial Mediterranean fever.

I Melamed, Y Shemer, V Zakuth, E Tzehoval, M Pras, Z Spirer
PMCID: PMC1535657  PMID: 6225577

Abstract

Familial Mediterranean fever (FMF) is a genetic disorder with an obscure aetiology. In attempts to investigate a possible immunoregulatory imbalance involved in this disease we tested 24 FMF patients for suppressor T cell activity and for chemotaxis of mononuclear cells. The suppressor T cell activity and chemotaxis were decreased in untreated FMF patients as compared to colchicine treated patients or normal controls. Amyloid FMF patients manifested significantly increased chemotactic activity, while the suppressor T cell activity was normal. This finding may extend our knowledge concerning the immune mechanism involved in FMF.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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