Abstract
Twenty-seven per cent of atopic patients initially presenting with infantile eczema or hay fever were defective for yeast opsonization and 18% had low levels of C2; these deficiencies were mutually exclusive, suggesting that they are primary. Both defects were associated with each of four different atopic syndromes, some of which were related to certain HLA haplotypes.
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Selected References
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- Brostoff J., Johns P., Stanworth D. R. Complexed IgE in atopy. Lancet. 1977 Oct 8;2(8041):741–742. doi: 10.1016/s0140-6736(77)90240-9. [DOI] [PubMed] [Google Scholar]
- Gibson D. J., Glass D., Carpenter C. B., Schur P. H. Hereditary C2 deficiency: diagnosis and HLA gene complex associations. J Immunol. 1976 Apr;116(4):1065–1070. [PubMed] [Google Scholar]
- Glass D., Raum D., Gibson D., Stillman J. S., Schur P. H. Inherited deficiency of the second component of complement. Rheumatic disease associations. J Clin Invest. 1976 Oct;58(4):853–861. doi: 10.1172/JCI108538. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jarrett E. E., Haig D. M., McDougall W., McNulty E. Rat IgE production. II. Primary and booster reaginic antibody responses following intradermal or oral immunization. Immunology. 1976 May;30(5):671–677. [PMC free article] [PubMed] [Google Scholar]
- Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965 Sep;2(3):235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
- Soothill J. F., Harvey B. A. A defect of the alternative pathway of complement. Clin Exp Immunol. 1977 Jan;27(1):30–33. [PMC free article] [PubMed] [Google Scholar]
- Soothill J. F., Harvey B. A. Defective opsonization. A common immunity deficiency. Arch Dis Child. 1976 Feb;51(2):91–99. doi: 10.1136/adc.51.2.91. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Soothill J. F. President's address. Some intrinsic and extrinsic factors predisposing to allergy. Proc R Soc Med. 1976 Jun;69(6):439–442. [PMC free article] [PubMed] [Google Scholar]
- Turner M. W., Brostoff T. J., Wells R. S., Stokes C. R., Soothill J. F. HLA in eczema and hay fever. Clin Exp Immunol. 1977 Jan;27(1):43–47. [PMC free article] [PubMed] [Google Scholar]
- Yamamura M., Valdimarsson H. A new semiquantitative radiometric opsonin assay. Selective measurement of opsonizing capacity of the alternative pathway. Immunology. 1978 Apr;34(4):689–694. [PMC free article] [PubMed] [Google Scholar]