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. 1979 Apr;36(1):71–77.

Induction of human antigen-specific and non-specific helper factors in vitro.

F Kantor, M Feldmann
PMCID: PMC1537693  PMID: 89019

Abstract

Human peripheral blood leucocytes, cultured for 4--6 days with the appropriate concentration of protein or synthetic polypeptide antigen, yield helper cells. These cells, after a further 24 hr incubation with the appropriate antigen release helper factors, which are of two types, antigen specific and non-specific; a similar situation to that described in the mouse. These factors are assayed by their effects on the plaque-forming cell response of mouse spleen cells cultures in vitro. The potential applications of this new assay for human T cell function are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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