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. 1976 Apr;24(1):18–25.

Antibodies for T lymphocytes in systemic lupus erythematosus.

G Michlmayr, C Pathouli, C Huber, H Huber
PMCID: PMC1538498  PMID: 1084815

Abstract

Sera of twenty-four patients with systemic lupus erythematosus were evaluated for antibodies cytotoxic for autologous lymphocytes. Such antibodies were domenstrable in twenty-two of these sera, whereas only one out of twenty patients with other connective tissue or lymphoproliferative disease showed a positive test. The antibodies remained detectable even when the patients went into remission. Sera containing the lymphocytotoxic antibodies were tested on cell fractions enriched for T or B lymphocytes. Primarily T lumphocytes wree affected by these antibodies. The presence of antibodies cytotoxic for T lymphocytes corresponded with a deficit of circulating T lymphocytes observed in most of our patients with systemic lupus erythematosys.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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