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. 1977 May;28(2):268–275.

Immunological studies of patients with asbestosis. II, Studies of circulating lymphoid cell numbers and humoral immunity.

E Kagan, A Solomon, J C Cochrane, P Kuba, P H Rocks, I Webster
PMCID: PMC1540752  PMID: 301449

Abstract

As part of an overall assessment of immunological function, several aspects of humorial immunity and circulating lymphocyte subpopulations were evaluated in a group of twenty-six patients with radiographic evidence of parenchylmal asbestosis. Statistical comparisons were made between the patient group and a comparable group of forty-five controls. Both the percentages and absolute numbers of circulating T lymphocytes were significantly reduced in the patient group compared with controls. Significant elevations of salivary secretory IgA and of serum IgA, IgG, IgM and IgE were noted amongst the patients compared with the controls. Non-organ-specific autoantibodies and cold-reactive lymphocytotoxins were present in high frequency in the patients' sera. Neoplasms were detected in four of the patients. The possible significance of these findings is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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