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. 1986 May;64(2):330–333.

The simultaneous presence of Langerhans' cell and interdigitating cell antigenic markers on inflammatory dendritic cells.

V A Alegre, D M MacDonald, L W Poulter
PMCID: PMC1542349  PMID: 3527504

Abstract

Immunohistological studies have been performed on tissues from various dermatological conditions using two monoclonal antibodies, RFD1 and NA1/34. These reagents were used to determine whether antigen expression restricted to interdigitating cells (RFD1+) and Langerhans' cells (NA1/34+) in normal tissues might occur together on dendritic cells involved in cutaneous inflammatory reactions. The results presented demonstrate that in psoriasis, allergic contact dermatitis and atopic dermatitis a proportion of the inflammatory dendritic cells express both antigens.

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Selected References

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