Skip to main content
PMC home page
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1975 Mar;50(3):171–178. doi: 10.1136/adc.50.3.171

Infantile hypertrophic pyloric stenosis in Belfast, 1957-1969.

J A Dodge
PMCID: PMC1544518  PMID: 1170811

Abstract

Infants with hypertrophic pyloric stenosis born in Belfast during the 13 years 1957-1969 have been reviewed. Their distribution shows a bias towards higher social classes, breast feeding, and primogeniture. Obstetric factors and parental ages seem to be of no importance. More affected infants were born during winter months than would be expected. The overall incidence of infantile pyloric stenosis in this community has fallen during the period under review. Clinically, the patients started vomiting at a mean age of 22 days and it is recommended that the condition should not be called 'congenital'. The size of the tumour is mainly determined by the size of the patient, rather than by his age or duration of symptoms. Attention is drawn to the occurrence of haematemesis in 17-5% and melaena in 2-9% of infants. Jaundice occurred in 1-8% of patients in this series, and is attributed to the adverse effect of starvation on hepatic glucuronyl transferase activity. Other conditions noted in these patients included inguinal hernia, partial thoracic stomach, and phenylketonuria. Subsequent growth and development were in the anticipated range.

Full text

PDF
173

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Carson N. A., Carré I. J., Neill D. W. Results of routine screening for phenylketonuria in early infancy, Northern Ireland (1960-67). Arch Dis Child. 1968 Apr;43(228):145–146. doi: 10.1136/adc.43.228.145. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Carter C. O., Evans K. A. Inheritance of congenital pyloric stenosis. J Med Genet. 1969 Sep;6(3):233–254. doi: 10.1136/jmg.6.3.233. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Chaves-Carballo E., Harris L. E., Lynn H. B. Jaundice associated with pyloric stenosis and neonatal small-bowel obstructions. Clin Pediatr (Phila) 1968 Apr;7(4):198–202. doi: 10.1177/000992286800700407. [DOI] [PubMed] [Google Scholar]
  4. Dodge J. A. Production of duodenal ulcers and hypertrophic pyloric stenosis by administration of pentagastrin to pregnant and newborn dogs. Nature. 1970 Jan 17;225(5229):284–285. doi: 10.1038/225284a0. [DOI] [PubMed] [Google Scholar]
  5. Dougall A. J. Infantile pyloric stenosis. A review of 200 cases. Scott Med J. 1969 May;14(5):156–161. doi: 10.1177/003693306901400502. [DOI] [PubMed] [Google Scholar]
  6. GERRARD J. W., WATERHOUSE J. A., MAURICE D. G. Infantile pyloric stenosis. Arch Dis Child. 1955 Dec;30(154):493–496. doi: 10.1136/adc.30.154.493. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. HERWEG J. C., MIDDELKAMP J. N., THORNTON H. K., REED C. A. A search into the etiology of hypertrophic pyloric stenosis. J Pediatr. 1962 Aug;61:309–310. doi: 10.1016/s0022-3476(62)80292-3. [DOI] [PubMed] [Google Scholar]
  8. Kwok R. H., Avery G. Seasonal variation of congenital hypertrophic pyloric stenosis. J Pediatr. 1967 Jun;70(6):963–965. doi: 10.1016/s0022-3476(67)80272-5. [DOI] [PubMed] [Google Scholar]
  9. MCLEAN M. M. The incidence of infantile pyloric stenosis in the north-east of Scotland. Arch Dis Child. 1956 Dec;31(160):481–482. doi: 10.1136/adc.31.160.481. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Marion J., Daudet M., Freidel M. Données nouvelles servant à l'interprétation des ictères accompagnant les sténoses hypertrophiques du pylore. Pediatrie. 1967 Sep;22(6):649–656. [PubMed] [Google Scholar]
  11. McKEOWN T., MacMAHON B., RECORD R. G. Size of tumour in infantile pyloric stenosis related to age at operation. Lancet. 1951 Sep 29;2(6683):556–558. doi: 10.1016/s0140-6736(51)93112-1. [DOI] [PubMed] [Google Scholar]
  12. Owens D., Sherlock S. Diagnosis of Gilbert's syndrome: role of reduced caloric intake test. Br Med J. 1973 Sep 15;3(5880):559–563. doi: 10.1136/bmj.3.5880.559. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. SIENIAWSKA M., WROBLEWSKA-KALUZEWSKA M. HIPERBILIRUBINEMIA W PRZEBIEGU PRZEROSTOWEGO ZW EZENIA OD'ZWIERNIKA. Pediatr Pol. 1964 Oct;39:1179–1185. [PubMed] [Google Scholar]
  14. Schärli A., Sieber W. K., Kiesewetter W. B. Hypertrophic pyloric stenosis at the Children's Hospital of Pittsburgh from 1912 to 1967. A critical review of current problems and complications. J Pediatr Surg. 1969 Feb;4(1):108–114. doi: 10.1016/0022-3468(69)90190-0. [DOI] [PubMed] [Google Scholar]
  15. Tanner J. M., Whitehouse R. H., Takaishi M. Standards from birth to maturity for height, weight, height velocity, and weight velocity: British children, 1965. I. Arch Dis Child. 1966 Oct;41(219):454–471. doi: 10.1136/adc.41.219.454. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. WALLGREN A. Is the rate of hypertrophic pyloric stenosis declining? Acta Paediatr. 1960 Jul;49:530–535. doi: 10.1111/j.1651-2227.1960.tb07768.x. [DOI] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES