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. 1976 May;51(5):327–336. doi: 10.1136/adc.51.5.327

15-Year developmental study on effects of severe undernutrition during infancy on subsequent physical growth and intellectual functioning.

M B Stoch, P M Smythe
PMCID: PMC1545984  PMID: 938077

Abstract

This third 5-year follow-up on the effects of severe undernutrition during infancy on subsequent brain growth and intellectual development confirms the level of gross retardation of intellect in the undernourished group when compared with the controls. As the subjects are now 15-18 years of age this must be permanent. All but 5 of the undernourished group are now living in conditions comparable to the controls. Improved nutrition is manifest by catch-up in height, in that the mean difference between undernourished subjects and controls has decreased by 2-73 cm. Remarkably, the difference in head circumference has increased by 0-5 cm, the mean head circumference of the undernourished now being 2-8 cm less than that of the controls. The Bender Gestalt and Human Figure Drawing tests did not correlate with the intelligence tests, indicating a separate deficit of a marked disturbance of visual-motor perception in 17 of the undernourished subjects, in 9 of whom these tests were highly significant of minimal brain dysfunction (5 of the controls). In retrospect there is much evidence to suggest the controls were also suboptimal; 8 controls had abnormal electroencephalograms as did 6 of the undernourished group.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Dobbing J. The later growth of the brain and its vulnerability. Pediatrics. 1974 Jan;53(1):2–6. [PubMed] [Google Scholar]
  2. Evans D. E., Moodie A. D., Hansen J. D. Kwashiorkor and intellectual development. S Afr Med J. 1971 Dec 25;45(49):1413–1426. [PubMed] [Google Scholar]
  3. Hertzig M. E., Birch H. G., Richardson S. A., Tizard J. Intellectual levels of school children severely malnourished during the first two years of life. Pediatrics. 1972 Jun;49(6):814–824. [PubMed] [Google Scholar]
  4. ROBERTSON I. Weight charts of coloured infants and preschool children. S Afr Med J. 1961 Jun 10;35:466–467. [PubMed] [Google Scholar]
  5. Stoch M. B., Smythe P. M. The effect of undernutrition during infancy on subsequent brain growth and intellectual development. S Afr Med J. 1967 Oct 28;41(41):1027–1030. [PubMed] [Google Scholar]
  6. Winick M. Cellular growth during early malnutrition. Pediatrics. 1971 Jun;47(6):969–978. [PubMed] [Google Scholar]
  7. Winick M., Rosso P. Head circumference and cellular growth of the brain in normal and marasmic children. J Pediatr. 1969 May;74(5):774–778. doi: 10.1016/s0022-3476(69)80140-x. [DOI] [PubMed] [Google Scholar]

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