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. 1969 Nov;10(11):921–923. doi: 10.1136/gut.10.11.921

Transmural electrical potential difference of the human colon

Michael G Geall, Robert J Spencer, Sidney F Phillips
PMCID: PMC1553059  PMID: 5358583

Abstract

The electrical potential across the human colon was measured by a technique which accurately reflects the true mucosa-to-serosa potential difference. Large negative mucosal potentials were recorded from all regions. The potential difference of the sigmoid colon was significantly greater than that of the rectum. The technique may have important applications to the further study of normal or abnormal colonic function.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BAILLIEN M., SCHOFFENIELS E. [Origin of the bioelectric potentials of the intestinal epithelium of the Greek tortoise]. Biochim Biophys Acta. 1961 Nov 11;53:537–548. doi: 10.1016/0006-3002(61)90213-x. [DOI] [PubMed] [Google Scholar]
  2. CLARKSON T. W., CROSS A. C., TOOLE S. R. Electrical potentials across isolated small intestine of the rat. Am J Physiol. 1961 Jun;200:1233–1235. doi: 10.1152/ajplegacy.1961.200.6.1233. [DOI] [PubMed] [Google Scholar]
  3. COOPERSTEIN I. L., BROCKMAN S. K. The electrical potential difference generated by the large intestine: its relation to electrolyte and water transfer. J Clin Invest. 1959 Feb;38(2):435–442. doi: 10.1172/JCI103818. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. COOPERSTEIN I. L., HOGBEN C. A. Ionic transfer across the isolated frog large intestine. J Gen Physiol. 1959 Jan 20;42(3):461–473. doi: 10.1085/jgp.42.3.461. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. CURRAN P. F., SCHWARTZ G. F. Na, Cl, and water transport by rat colon. J Gen Physiol. 1960 Jan;43:555–571. doi: 10.1085/jgp.43.3.555. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Devroede G. J., Phillips S. F. Conservation of sodium, chloride, and water by the human colon. Gastroenterology. 1969 Jan;56(1):101–109. [PubMed] [Google Scholar]
  7. Schmid W. C., Phillips S. F., Summerskill W. H. Jejunal secretion of electrolytes and water in nontropical sprue. J Lab Clin Med. 1969 May;73(5):772–783. [PubMed] [Google Scholar]

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