Abstract
We conducted a case-control, interview-based study of the risk of developing cancer from asbestos in drinking water. An area that included Everett, Washington, was selected for the study because of the unusually high concentration of chrysotile asbestos in drinking water from the Sultan River. Through a population-based tumor registry, 382 individuals with cancer of the buccal cavity, pharynx, respiratory system, digestive system, bladder, or kidneys, diagnosed between 1977 and 1980, were identified, and they or their next of kin were interviewed. We conducted validation checks of our interviews, including a comparison with secondary sources. Data on asbestos exposure were collected based on residence and workplace history, and on individual water consumption. Logistic regression was used to estimate cancer risk. We found no convincing evidence for increased cancer risk from imbibed asbestos. Confidence intervals for relative risks for almost all sites included unity. There were significantly elevated risks only for male stomach and male pharyngeal cancer, but these sex-inconsistent results, based on small numbers of cases, are probably due to other factors.
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- Conforti P. M., Kanarek M. S., Jackson L. A., Cooper R. C., Murchio J. C. Asbestos in drinking water and cancer in the San Francisco Bay Area: 1969-1974 incidence. J Chronic Dis. 1981;34(5):211–224. doi: 10.1016/0021-9681(81)90065-5. [DOI] [PubMed] [Google Scholar]
- Cook P. M., Glass G. E., Tucker J. H. Asbestiform amphibole minerals: detection and measurement of high concentrations in municipal water supplies. Science. 1974 Sep 6;185(4154):853–855. doi: 10.1126/science.185.4154.853. [DOI] [PubMed] [Google Scholar]
- Cunningham H. M., Pontefract R. Asbestos fibres in beverages and drinking water. Nature. 1971 Jul 30;232(5309):332–333. doi: 10.1038/232332a0. [DOI] [PubMed] [Google Scholar]
- Enterline P. E., Kendrick M. A. Asbestos-dust exposures at various levels and mortality. Arch Environ Health. 1967 Aug;15(2):181–186. doi: 10.1080/00039896.1967.10664900. [DOI] [PubMed] [Google Scholar]
- Gordis L. Should dead cases be matched to dead controls? Am J Epidemiol. 1982 Jan;115(1):1–5. doi: 10.1093/oxfordjournals.aje.a113263. [DOI] [PubMed] [Google Scholar]
- Harrington J. M., Craun G. F., Meigs J. W., Landrigan P. J., Flannery J. T., Woodhull R. S. An investigation of the use of asbestos cement pipe for public water supply and the incidence of gastrointestinal cancer in Connecticut, 1935-1973. Am J Epidemiol. 1978 Feb;107(2):96–103. doi: 10.1093/oxfordjournals.aje.a112523. [DOI] [PubMed] [Google Scholar]
- Kanarek M. S., Conforti P. M., Jackson L. A., Cooper R. C., Murchio J. C. Asbestos in drinking water and cancer incidence in the San Francisco Bay area. Am J Epidemiol. 1980 Jul;112(1):54–72. doi: 10.1093/oxfordjournals.aje.a112976. [DOI] [PubMed] [Google Scholar]
- Levy B. S., Sigurdson E., Mandel J., Laudon E., Pearson J. Investigating possible effects of abestos in city water: surveillance of gastrointestinal cancer incidence in Duluth, Minnesota. Am J Epidemiol. 1976 Apr;103(4):362–368. doi: 10.1093/oxfordjournals.aje.a112235. [DOI] [PubMed] [Google Scholar]
- Masson T. J., McKay F. W., Miller R. W. Asbestos-like fibers in Duluth water supply. Relation to cancer mortality. JAMA. 1974 May 20;228(8):1019–1020. [PubMed] [Google Scholar]
- Millette J. R., Clark P. J., Pansing M. F., Twyman J. D. Concentration and size of asbestos in water supplies. Environ Health Perspect. 1980 Feb;34:13–25. doi: 10.1289/ehp.803413. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Polissar L., Severson R. K., Boatman E. S., Thomas D. B. Cancer incidence in relation to asbestos in drinking water in the Puget Sound region. Am J Epidemiol. 1982 Aug;116(2):314–328. doi: 10.1093/oxfordjournals.aje.a113415. [DOI] [PubMed] [Google Scholar]
- Prentice R. Use of the logistic model in retrospective studies. Biometrics. 1976 Sep;32(3):599–606. [PubMed] [Google Scholar]
- SELIKOFF I. J., CHURG J., HAMMOND E. C. ASBESTOS EXPOSURE AND NEOPLASIA. JAMA. 1964 Apr 6;188:22–26. doi: 10.1001/jama.1964.03060270028006. [DOI] [PubMed] [Google Scholar]
- Wigle D. T. Cancer mortality in relation to asbestos in municipal water supplies. Arch Environ Health. 1977 Jul-Aug;32(4):185–190. doi: 10.1080/00039896.1977.10667278. [DOI] [PubMed] [Google Scholar]