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. 1983 Jan;47:33–42. doi: 10.1289/ehp.834733

Assessment of the epidemiological data relating lung cancer to air pollution.

F E Speizer
PMCID: PMC1569407  PMID: 6337830

Abstract

The epidemiological data linking air pollution and lung cancer are derived from statistical associations concerning rates of cancer among urban and rural residents, migrant studies and studies of occupational groups exposed to effluents from fossil fuel combinations. Few, if any of these studies, are adequately adjusted for both relatively simple measures of cigarette smoking or the potentially more subtle effects of the duration of smoking. Because urbanization and industrial sources of air pollution correspond chronologically with the major increases in cigarette smoking, it is not likely that the specific attributable risk to each component can be adequately assessed. Interactions between cigarette smoking and specific air pollutants, similar to those seen between cigarette smoking and asbestos and or radiation, may be occurring. Considering the various estimates made over the last 25 years, it is likely that the effect of air pollution on lung cancer is something greater than zero; however, it is unlikely that the estimate exceeds 2% of all lung cancers or 5/100,000 cases in urban males. Thus, the effect on all cancers is likely to be less than 1% of all cases.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Carnow B. W., Meier P. Air pollution and pulmonary cancer. Arch Environ Health. 1973 Sep;27(3):207–218. doi: 10.1080/00039896.1973.10666353. [DOI] [PubMed] [Google Scholar]
  2. DOLL R., FISHER R. E., GAMMON E. J., GUNN W., HUGHES G. O., TYRER F. H., WILSON W. MORTALITY OF GASWORKERS WITH SPECIAL REFERENCE TO CANCERS OF THE LUNG AND BLADDER, CHRONIC BRONCHITIS, AND PNEUMOCONIOSIS. Br J Ind Med. 1965 Jan;22:1–12. doi: 10.1136/oem.22.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. DOLL R., HILL A. B. MORTALITY IN RELATION TO SMOKING: TEN YEARS' OBSERVATIONS OF BRITISH DOCTORS. Br Med J. 1964 May 30;1(5395):1399–1410. doi: 10.1136/bmj.1.5395.1399. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Doll R. Atmospheric pollution and lung cancer. Environ Health Perspect. 1978 Feb;22:23–31. doi: 10.1289/ehp.782223. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Doll R., Peto R. The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. J Natl Cancer Inst. 1981 Jun;66(6):1191–1308. [PubMed] [Google Scholar]
  6. Doll R., Vessey M. P., Beasley R. W., Buckley A. R., Fear E. C., Fisher R. E., Gammon E. J., Gunn W., Hughes G. O., Lee K. Mortality of gasworkers - final report of a prospective study. Br J Ind Med. 1972 Oct;29(4):394–406. doi: 10.1136/oem.29.4.394. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. HAENSZEL W., LOVELAND D. B., SIRKEN M. G. Lung-cancer mortality as related to residence and smoking histories. I. White males. J Natl Cancer Inst. 1962 Apr;28:947–1001. [PubMed] [Google Scholar]
  8. Hammond E. C., Garfinkel L. General air pollution and cancer in the United States. Prev Med. 1980 Mar;9(2):206–211. doi: 10.1016/0091-7435(80)90077-8. [DOI] [PubMed] [Google Scholar]
  9. Hammond E. C., Selikoff I. J., Lawther P. L., Seidman H. Inhalation of benzpyrene and cancer in man. Ann N Y Acad Sci. 1976;271:116–124. doi: 10.1111/j.1749-6632.1976.tb23100.x. [DOI] [PubMed] [Google Scholar]
  10. Higgins I. T. Epidemiological evidence on the carcinogenic risk of air pollution. IARC Sci Publ. 1976;(13):41–52. [PubMed] [Google Scholar]
  11. Järvholm B., Thiringer G. Epidemiological studies of lung cancer--influence of smoking habits. Eur J Respir Dis Suppl. 1980;107:125–129. [PubMed] [Google Scholar]
  12. KAPLAN I. Relationship of noxious gases to carcinoma of the lung in railroad workers. J Am Med Assoc. 1959 Dec 12;171:2039–2043. doi: 10.1001/jama.1959.03010330001001. [DOI] [PubMed] [Google Scholar]
  13. Lloyd J. W. Long-term mortality study of steelworkers. V. Respiratory cancer in coke plant workers. J Occup Med. 1971 Feb;13(2):53–68. [PubMed] [Google Scholar]
  14. RAFFLE P. A. The health of the worker. Br J Ind Med. 1957 Apr;14(2):73–80. doi: 10.1136/oem.14.2.73. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Redmond C. K., Strobino B. R., Cypess R. H. Cancer experience among coke by-product workers. Ann N Y Acad Sci. 1976;271:102–115. doi: 10.1111/j.1749-6632.1976.tb23099.x. [DOI] [PubMed] [Google Scholar]
  16. Reid D. D., Cornfield J., Markush R. E., Seigel D., Pedersen E., Haenszel W. Studies of disease among migrants and native populations in Great Britain, Norway, and the United States. 3. Prevalence of cardiorespiratory symptoms among migrants and native-born in the United States. Natl Cancer Inst Monogr. 1966 Jan;19:321–346. [PubMed] [Google Scholar]
  17. SAWICKI E., ELBERT W. C., HAUSER T. R., FOX F. T., STANLEY T. W. Benzo(a)pyrene content of the air of American communities. Am Ind Hyg Assoc J. 1960 Dec;21:443–451. doi: 10.1080/00028896009344103. [DOI] [PubMed] [Google Scholar]
  18. STOCKS P., CAMPBELL J. M. Lung cancer death rates among non-smokers and pipe and cigarette smokers; an evaluation in relation to air pollution by benzpyrene and other substances. Br Med J. 1955 Oct 15;2(4945):923–929. doi: 10.1136/bmj.2.4945.923. [DOI] [PMC free article] [PubMed] [Google Scholar]

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