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British Journal of Pharmacology and Chemotherapy logoLink to British Journal of Pharmacology and Chemotherapy
. 1968 Jun;33(2):266–276. doi: 10.1111/j.1476-5381.1968.tb00988.x

Kinetic parameters of narcotic agonists and antagonists, with particular reference to N-allylnoroxymorphone (naloxone).

H W Osterlitz, A J Watt
PMCID: PMC1570231  PMID: 5664147

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Blane G. F. Blockade of bradykinin-induced nociception in the rat as a test for analgesic drugs with particular reference to morphine antagonists. J Pharm Pharmacol. 1967 Jun;19(6):367–373. doi: 10.1111/j.2042-7158.1967.tb09562.x. [DOI] [PubMed] [Google Scholar]
  2. Blumberg H., Dayton H. B., Wolf P. S. Counteraction of narcotic antagonist analgesics by the narcotic antagonist Naloxone. Proc Soc Exp Biol Med. 1966 Dec;123(3):755–758. doi: 10.3181/00379727-123-31595. [DOI] [PubMed] [Google Scholar]
  3. EDDY N. B., HALBACH H., BRAENDEN O. J. Synthetic substances with morphine-like effect: clinical experience; potency, side-effects, addiction liability. Bull World Health Organ. 1957;17(4-5):569–863. [PMC free article] [PubMed] [Google Scholar]
  4. EDDY N. B., HALBACH H., BRAENDEN O. J. Synthetic substances with morphine-like effect; relationship between analgesic action and addiction liability, with a discussion of the chemical structure of addiction-producing substances. Bull World Health Organ. 1956;14(3):353–402. [PMC free article] [PubMed] [Google Scholar]
  5. FOLDES F. F., LUNN J. N., MOORE J., BROWN I. M. N-Allylnoroxy-morphone: a new potent narcotic antagonist. Am J Med Sci. 1963 Jan;245:23–30. [PubMed] [Google Scholar]
  6. FRASER H. F., ROSENBERG D. E. STUDIES ON THE HUMAN ADDICTION LIABILITY OF 2'-HYDROXY-5-9-DIMETHYL-2-(3,3-DIMETHYLALLYL)-6,7-BENZOMORPHAN (WIN 20,228): A WEAK NARCOTIC ANTAGONIST. J Pharmacol Exp Ther. 1964 Feb;143:149–156. [PubMed] [Google Scholar]
  7. Gyand E. A., Kosterlitz H. W. Agonist and antagonist actions of morphine-like drugs on the guinea-pig isolated ileum. Br J Pharmacol Chemother. 1966 Sep;27(3):514–527. doi: 10.1111/j.1476-5381.1966.tb01864.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Jasinski D. R., Martin W. R., Haertzen C. A. The human pharmacology and abuse potential of N-allylnoroxymorphone (naloxone). J Pharmacol Exp Ther. 1967 Aug;157(2):420–426. [PubMed] [Google Scholar]
  9. Lasagna L. Drug interaction in the field of analgesic drugs. Proc R Soc Med. 1965 Nov;58(11 Pt 2):978–983. [PMC free article] [PubMed] [Google Scholar]
  10. Martin W. R., Fraser H. F., Gorodetzky C. W., Rosenberg D. E. Studies of the dependence-producing potential of the narcotic antagonist 2-cyclopropylmethyl-2'-hydroxy-5,9-dimethyl-6,7-benzomorphan (cyclazocine, WIN-20,740, ARC II-c-3). J Pharmacol Exp Ther. 1965 Dec;150(3):426–436. [PubMed] [Google Scholar]
  11. Martin W. R., Gorodetzky C. W. Demonstration of tolerance to and physical dependence of N-allylnormorphine (nalorphine). J Pharmacol Exp Ther. 1965 Dec;150(3):437–442. [PubMed] [Google Scholar]
  12. McClane T. K., Martin W. R. Effects of morphine, nalorphine, cyclazocine, and naloxone on the flexor reflex. Int J Neuropharmacol. 1967 Mar;6(2):89–98. doi: 10.1016/0028-3908(67)90057-3. [DOI] [PubMed] [Google Scholar]
  13. SCHAUMANN W. Zusammenhänge zwischen der Wirkung der Analgetica und Sympathicomimetica auf den Meerschweinchen-Dunndarm. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1958;233(1):112–124. [PubMed] [Google Scholar]
  14. STEPHENSON R. P. A modification of receptor theory. Br J Pharmacol Chemother. 1956 Dec;11(4):379–393. doi: 10.1111/j.1476-5381.1956.tb00006.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. TELFORD J., PAPADOPOULOS C. N., KEATS A. S. Studies of analgesic drugs. VII. Morphine antagonists as analgesics. J Pharmacol Exp Ther. 1961 Jul;133:106–116. [PubMed] [Google Scholar]
  16. Winder C. V., Welford M., Wax J., Kaump D. H. Pharmacologic and toxicologic studies of m-(1-methyl-3-propyl-3-pyrrolidinyl)phenol (CI-572), an analgetic and antitussive agent. J Pharmacol Exp Ther. 1966 Oct;154(1):161–175. [PubMed] [Google Scholar]

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