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. 1967 Jan;2(1):71–82.

Moniliasis, `autoimmune' polyendocrinopathy, and immunologic family study

K D Wuepper, H H Fudenberg
PMCID: PMC1578812  PMID: 6030796

Abstract

A patient with chronic mucocutaneous moniliasis of 17 years' duration developed bilateral keratitis, hepatitis and steatorrhea, conditions often found in association with coexistent adrenocortical and parathyroid insufficiency. Immunologic studies showed that the patient's serum contained organ-specific antibodies. Further clinical investigation demonstrated adrenal and thyroid insufficiency; parathyroid function was normal. Immunologic abnormalities were also detected in seventeen members of his family, indicating a possible familial predisposition to `autoimmune' disease. A review of the literature suggested that the patient may have an incomplete form of a syndrome consisting primarily of idiopathic Addison's disease, hypoparathyroidism and moniliasis.

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Selected References

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