Skip to main content
British Medical Journal logoLink to British Medical Journal
. 1973 Aug 11;3(5875):339–343. doi: 10.1136/bmj.3.5875.339

Drug-induced Blood Dyscrasias in Sweden

L E Böttiger, B Westerholm
PMCID: PMC1586480  PMID: 4723818

Abstract

Cases of drug-induced aplastic anaemia, haemolytic anaemia, thrombocytopenia, and agranulocytosis reported to the Swedish Adverse Drug Reaction Committee during the five-year period 1966-70 have been analysed and compared with cases of the same cytopenias from “all” causes. Oral diuretics were a dominant cause of drug-induced thrombocytopenia, methyldopa of haemolytic anaemia, and oxyphenbutazone of aplastic anaemia. Computer systems should help such studies, particularly in showing a changing pattern of complications and causes.

Full text

PDF
339

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Böttiger L. E., Westerholm B. Acquired haemolytic anaemia. I. Incidence and aetiology. Acta Med Scand. 1973 Mar;193(3):223–226. [PubMed] [Google Scholar]
  2. Böttiger L. E., Westerholm B. Aplastic anaemia. I. Incidence and aetiology. Acta Med Scand. 1972 Oct;192(4):315–318. [PubMed] [Google Scholar]
  3. Böttiger L. E., Westerholm B. Aplastic anaemia. II. Drug-induced aplastic anaemia. Acta Med Scand. 1972 Oct;192(4):319–321. [PubMed] [Google Scholar]
  4. Böttiger L. E., Westerholm B. Thrombocytopenia. I. Incidence and aetiology. Acta Med Scand. 1972 Jun;191(6):535–540. [PubMed] [Google Scholar]
  5. Böttiger L. E., Westerholm B. Thrombocytopenia. II. Drug-induced thrombocytopenia. Acta Med Scand. 1972 Jun;191(6):541–548. [PubMed] [Google Scholar]
  6. Dausset J., Contu L. Drug-induced hemolysis. Annu Rev Med. 1967;18:55–70. doi: 10.1146/annurev.me.18.020167.000415. [DOI] [PubMed] [Google Scholar]
  7. Hurwitz N., Wade O. L. Intensive hospital monitoring of adverse reactions to drugs. Br Med J. 1969 Mar 1;1(5643):531–536. doi: 10.1136/bmj.1.5643.531. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Jick H., Miettinen O. S., Shapiro S., Lewis G. P., Siskind V., Slone D. Comprehensive drug surveillance. JAMA. 1970 Aug 31;213(9):1455–1460. [PubMed] [Google Scholar]
  9. SCHWARTZ W. S. Management of common pulmonary diseases. JAMA. 1962 Jul 14;181:134–141. doi: 10.1001/jama.1962.03050280064005i. [DOI] [PubMed] [Google Scholar]
  10. Wallerstein R. O., Condit P. K., Kasper C. K., Brown J. W., Morrison F. R. Statewide study of chloramphenicol therapy and fatal aplastic anemia. JAMA. 1969 Jun 16;208(11):2045–2050. [PubMed] [Google Scholar]
  11. Worlledge S. M., Carstairs K. C., Dacie J. V. Autoimmune haemolytic anaemia associated with alpha-methyldopa therapy. Lancet. 1966 Jul 16;2(7455):135–139. doi: 10.1016/s0140-6736(66)92423-8. [DOI] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES