Abstract
All 433 patients with colorectal cancer who presented in the north-east of Scotland during 1968 and 1969 were followed up for seven years or until death intervened. The incidence of colorectal cancer in the region was the highest recorded in Great Britain. Half the patients were incurable at the time of diagnosis. Nevertheless, of the 195 survivors of radical resection 146 (75%) did not die of carcinoma during the next seven years. Men with "curable" rectal cancer showed a substantially lower corrected survival rate (42%) than women (70%), but this was due to intercurrent disease not recurrence. Comparable figures for colonic carcinoma showed no difference between men (75%) and women (77%). The overall picture of colorectal cancer has apparently not changed for 20 years. Nevertheless, earlier diagnosis and timely operation--possibly with adjuvant chemotherapy--may produce useful long-term results.
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- COOKE R. V. Advanced carcinoma of the colon with emphasis on the inflammatory factor. Ann R Coll Surg Engl. 1956 Jan;18(1):46–61. [PMC free article] [PubMed] [Google Scholar]
- Cutler S. J. Trends in cancers of the digestive tract. Surgery. 1969 May;65(5):740–752. [PubMed] [Google Scholar]
- Elliot M. S., Louw J. H. A 10-year survey of large bowel carcinoma at Groote Schuur Hospital with particular reference to patients under 30 years of age. Br J Surg. 1979 Sep;66(9):621–624. doi: 10.1002/bjs.1800660907. [DOI] [PubMed] [Google Scholar]
- Holliday H. W., Hardcastle J. D. Delay in diagnosis and treatment of symptomatic colorectal cancer. Lancet. 1979 Feb 10;1(8111):309–311. doi: 10.1016/s0140-6736(79)90718-9. [DOI] [PubMed] [Google Scholar]
- Lanier A. P., Wychulis A. R., Dockerty M. B., Elveback L. R., Beahrs O. H., Kurland L. T. Colorectal cancer in Rochester, Minnesota 1940-1969. Cancer. 1973 Mar;31(3):606–615. doi: 10.1002/1097-0142(197303)31:3<606::aid-cncr2820310317>3.0.co;2-g. [DOI] [PubMed] [Google Scholar]
- Lockhart-Mummery H. E., Ritchie J. K., Hawley P. R. The results of surgical treatment for carcinoma of the rectum of St Mark's Hospital from 1948 to 1972. Br J Surg. 1976 Sep;63(9):673–677. doi: 10.1002/bjs.1800630902. [DOI] [PubMed] [Google Scholar]
- Morson B. C. The pathogenesis of colorectal cancer. Introduction. Major Probl Pathol. 1978;10:1–13. [PubMed] [Google Scholar]
- Slaney G. Results of treatment of carcinoma of the colon and rectum. Mod Trends Surg. 1971;3:69–89. [PubMed] [Google Scholar]
- Taylor I., Brooman P., Rowling J. T. Adjuvant liver perfusion in colorectal cancer: initial results of a clinical trial. Br Med J. 1977 Nov 19;2(6098):1320–1322. doi: 10.1136/bmj.2.6098.1320. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Whittaker M., Goligher J. C. The prognosis after surgical treatment for carcinoma of the rectum. Br J Surg. 1976 May;63(5):384–388. doi: 10.1002/bjs.1800630513. [DOI] [PubMed] [Google Scholar]