Abstract
The prognosis and pathological findings in 44 patients with breast cancer who had taken contraceptive steroids during the year before diagnosis were compared with those in 44 controls matched for age and parity. No significant differences between the two groups were found in the histological features of the tumour or extent of axillary lymph-node disease. In patients with axillary node disease the recurrence rate in the controls was significantly higher than in the study group and more of the control patients had died. It is concluded that oral contraceptives have no untoward effect on the prognosis of breast cancer.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BLACK M. M., SPEER F. D. Sinus histiocytosis of lymph nodes in cancer. Surg Gynecol Obstet. 1958 Feb;106(2):163–175. [PubMed] [Google Scholar]
- BLOOM H. J., RICHARDSON W. W. Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years. Br J Cancer. 1957 Sep;11(3):359–377. doi: 10.1038/bjc.1957.43. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Carter A. C., Sedransk N., Kelley R. M., Ansfield F. J., Ravdin R. G., Talley R. W., Potter N. R. Diethylstilbestrol: recommended dosages for different categories of breast cancer patients. Report of the Cooperative Breast Cancer Group. JAMA. 1977 May 9;237(19):2079–2078. [PubMed] [Google Scholar]
- Cutler S. J., Black M. M., Friedell G. H., Vidone R. A., Goldenberg I. S. Prognostic factors in cancer of the female breast. II. Reproducibility of histopathologic classification. Cancer. 1966 Jan;19(1):75–82. doi: 10.1002/1097-0142(196601)19:1<75::aid-cncr2820190108>3.0.co;2-4. [DOI] [PubMed] [Google Scholar]
- Fasal E., Paffenbarger R. S., Jr Oral contraceptives as related to cancer and benign lesions of the breast. J Natl Cancer Inst. 1975 Oct;55(4):767–773. doi: 10.1093/jnci/55.4.767. [DOI] [PubMed] [Google Scholar]
- Fechner R. E. Breast cancer during oral contraceptive therapy. Cancer. 1970 Dec;26(6):1204–1211. doi: 10.1002/1097-0142(197012)26:6<1204::aid-cncr2820260605>3.0.co;2-h. [DOI] [PubMed] [Google Scholar]
- NATHANSON I. T., KELLEY R. M. Hormonal treatment of cancer. N Engl J Med. 1952 Jan 24;246(4):135–contd. doi: 10.1056/NEJM195201242460405. [DOI] [PubMed] [Google Scholar]
- Vessey M. P., Doll R., Jones K. Oral contraceptives and breast cancer. Progress report of an epidemiological study. Lancet. 1975 Apr 26;1(7913):941–943. doi: 10.1016/s0140-6736(75)92005-x. [DOI] [PubMed] [Google Scholar]
- Vessey M. P., Doll R., Sutton P. M. Oral contraceptives and breast neoplasia: a retrospective study. Br Med J. 1972 Sep 23;3(5829):719–724. doi: 10.1136/bmj.3.5829.719. [DOI] [PMC free article] [PubMed] [Google Scholar]