Abstract
Shigella dysentery caused 65% of all cases of acute renal failure (ARF) seen in children treated at the Christian Medical College Hospital, Vellore, during the 33 months ending September 1977. In the 40 children with ARF secondary to shigella dysentery, haematological findings suggested that they were suffering from the haemolytic-uraemic syndrome, and glomerular hypercellularity and fibrin deposition were present in all 12 patients whose renal histology could be studied. Peritoneal dialysis was the main element of treatment: 43% of children who underwent dialysis improved, compared with only 25% of those who did not undergo dialysis. The haemolytic-uraemic syndrome precipitated by bacillary dystentery is therefore the most important cause of ARF in children aged under 5 years in Tamil Nadu and the adjoining area of Andhra Pradesh.
Full text
PDFImages in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Avalos J. S., Vitacco M., Molinas F., Peñalver J., Gianantonio C. Coagulation studies in the hemolytic-uremic syndrome. J Pediatr. 1970 Apr;76(4):538–548. doi: 10.1016/s0022-3476(70)80403-6. [DOI] [PubMed] [Google Scholar]
- Baker N. M., Mills A. E., Rachman I., Thomas J. E. Haemolytic-uraemic syndrome in typhoid fever. Br Med J. 1974 Apr 13;2(5910):84–87. doi: 10.1136/bmj.2.5910.84. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bhat P., Myers R. M., Feldman R. A. Significance of the incidence of Shigella infection as indicated by results of a longitudinal study. Jpn J Med Sci Biol. 1970 Aug;23(4):237–242. doi: 10.7883/yoken1952.23.237. [DOI] [PubMed] [Google Scholar]
- Chan J. C., Eleff M. G., Campbell R. A. The hemolytic-uremic syndrome in nonrelated adopted siblings. J Pediatr. 1969 Dec;75(6):1050–1053. doi: 10.1016/s0022-3476(69)80346-x. [DOI] [PubMed] [Google Scholar]
- GIANANTONIO C., VITACCO M., MENDILAHARZU F., RUTTY A., MENDILAHARZU J. THE HEMOLYTIC-UREMIC SYNDROME. J Pediatr. 1964 Apr;64:478–491. doi: 10.1016/s0022-3476(64)80337-1. [DOI] [PubMed] [Google Scholar]
- Gianantonio C. A., Vitacco M., Mendilaharzu F., Gallo G. E., Sojo E. T. The hemolytic-uremic syndrome. Nephron. 1973;11(2):174–192. doi: 10.1159/000180229. [DOI] [PubMed] [Google Scholar]
- Glasgow L. A., Balduzzi P. Isolation of Coxsackie virus group A, type 4, from a patient with hemolytic-uremic syndrome. N Engl J Med. 1965 Sep 30;273(14):754–756. doi: 10.1056/NEJM196509302731407. [DOI] [PubMed] [Google Scholar]
- Jadhav M., Verghese R., Bhat P., Webb J. K. Clinical and microbiological features of shigellosis in 100 South Indian infants and children under 5 years. Indian Pediatr. 1966 Nov;3(11):393–400. [PubMed] [Google Scholar]
- Kaplan B. S., Thomson P. D., de Chadarévian J. P. The hemolytic uremic syndrome. Pediatr Clin North Am. 1976 Nov;23(4):761–777. doi: 10.1016/s0031-3955(16)33359-4. [DOI] [PubMed] [Google Scholar]
- Lieberman E. Hemolytic-uremic syndrome. J Pediatr. 1972 Jan;80(1):1–16. doi: 10.1016/s0022-3476(72)80445-1. [DOI] [PubMed] [Google Scholar]
- Lieberman E. Management of acute renal failure in infants and children. Nephron. 1973;11(2):193–208. doi: 10.1159/000180230. [DOI] [PubMed] [Google Scholar]
- McLean M. M., Jones C. H., Sutherland D. A. Haemolytic-uraemic syndrome. A report of an outbreak. Arch Dis Child. 1966 Feb;41(215):76–81. doi: 10.1136/adc.41.215.76. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ray C. G., Tucker V. L., Harris D. J., Cuppage F. E., Chin T. D. Enteroviruses associated with the hemolytic-uremic syndrome. Pediatrics. 1970 Sep;46(3):378–388. [PubMed] [Google Scholar]
- Sharpstone P., Evans R. G., O'Shea M., Alexander L., Lee H. A. Haemolytic-uraemic syndrome: survival after prolonged oliguria. Arch Dis Child. 1968 Dec;43(232):711–716. doi: 10.1136/adc.43.232.711. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Shashaty G. G., Atamer M. A. Hemolytic uremic syndrome associated with infectious mononucleosis. Am J Dis Child. 1974 May;127(5):720–722. doi: 10.1001/archpedi.1974.02110240106016. [DOI] [PubMed] [Google Scholar]
- Vitsky B. H., Suzuki Y., Strauss L., Churg J. The hemolytic-uremic syndrome: a study of renal pathologic alterations. Am J Pathol. 1969 Dec;57(3):627–647. [PMC free article] [PubMed] [Google Scholar]