Abstract
A total of 21 patients suffering from drug-induced rashes from practolol have been seen over the past two years. The clinical manifestations varied, with the morphological appearances of the rash resembling those of eczema, lupus erythematosus, lichen planus, and a highly characteristic toxic erythematous psoriasiform eruption. Persistent ocular damage was a feature in three cases.
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- Alarcón-Segovia D. Drug-induced lupus syndromes. Mayo Clin Proc. 1969 Sep;44(9):664–681. [PubMed] [Google Scholar]
- Felix R. H., Comaish J. S. The value of patch and other skin tests in drug eruptions. Lancet. 1974 May 25;1(7865):1017–1019. doi: 10.1016/s0140-6736(74)90417-6. [DOI] [PubMed] [Google Scholar]
- George C. F., Nagle R. E., Pentecost B. L. Practolol in treatment of angina pectoris. A double-blind trial. Br Med J. 1970 May 16;2(5706):402–404. doi: 10.1136/bmj.2.5706.402. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hughes G. R. Significance of anti-D.N.A. antibodies in systemic lupus erythematosus. Lancet. 1971 Oct 16;2(7729):861–863. doi: 10.1016/s0140-6736(71)90234-0. [DOI] [PubMed] [Google Scholar]
- Raftery E. B., Denman A. M. Systemic lupus erythematosus syndrome induced by practolol. Br Med J. 1973 May 26;2(5864):452–455. doi: 10.1136/bmj.2.5864.452. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rowland M. G., Stevenson C. J. Exfoliative dermatitis and practolol. Lancet. 1972 May 20;1(7760):1130–1130. doi: 10.1016/s0140-6736(72)91482-1. [DOI] [PubMed] [Google Scholar]
- Sandler G., Clayton G. A. Clinical evaluation of practolol, a new cardioselective beta-blocking agent in angina pectoris. Br Med J. 1970 May 16;2(5706):399–402. doi: 10.1136/bmj.2.5706.399. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tan R. S. Thymoma, acquired hypogammaglobulinaemia, lichen planus, alopecia areata. Proc R Soc Med. 1974 Mar;67(3):196–198. [PMC free article] [PubMed] [Google Scholar]