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. 1994 May;84(5):830–835. doi: 10.2105/ajph.84.5.830

The logic in ecological: II. The logic of design.

M Susser
PMCID: PMC1615022  PMID: 8179057

Abstract

The utility of ecological studies is considered in terms of the salience of their designs and is exemplified in four levels: obligate and apt; optional and apt; optional, not apt but convenient; and maladroit (neither obligate, apt, nor justifiable by convenience). Ecological studies are obligate when they are the only choice available, either because of the question asked (as in testing differences between groups and discovering group effects), or where there are "dependent happenings" (as in transactions involving more than one individual), or because individual data are lacking. Apt studies are logically appropriate; analysis and results are not extrapolated beyond necessity or without precautions. Obligate studies enforced by lack of individual data may be apt or less than apt. Optional ecological studies may be apt or, if less than apt, they may yet be convenient. Maladroit studies are neither obligate, apt, nor convenient. Each class of study is illustrated by examples ordered according to a standard design hierarchy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aaby P., Bukh J., Lisse I. M., Seim E., de Silva M. C. Increased perinatal mortality among children of mothers exposed to measles during pregnancy. Lancet. 1988 Mar 5;1(8584):516–519. doi: 10.1016/s0140-6736(88)91306-2. [DOI] [PubMed] [Google Scholar]
  2. Aaby P., Seim E., Knudsen K., Bukh J., Lisse I. M., da Silva M. C. Increased postperinatal child mortality among children of mothers exposed to measles during pregnancy. Am J Epidemiol. 1990 Sep;132(3):531–539. doi: 10.1093/oxfordjournals.aje.a115689. [DOI] [PubMed] [Google Scholar]
  3. Chalmers T. C., Levin H., Sacks H. S., Reitman D., Berrier J., Nagalingam R. Meta-analysis of clinical trials as a scientific discipline. I: Control of bias and comparison with large co-operative trials. Stat Med. 1987 Apr-May;6(3):315–328. doi: 10.1002/sim.4780060320. [DOI] [PubMed] [Google Scholar]
  4. DEAN G. Disseminated sclerosis in South Africa; its relationship to swayback disease and suggested treatment. Br Med J. 1949 May 14;1(4610):842–845. doi: 10.1136/bmj.1.4610.842. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Durkin M. S., Khan N., Davidson L. L., Zaman S. S., Stein Z. A. The effects of a natural disaster on child behavior: evidence for posttraumatic stress. Am J Public Health. 1993 Nov;83(11):1549–1553. doi: 10.2105/ajph.83.11.1549. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. FORRESTER R. M., STEIN Z., SUSSER M. W. A TRIAL OF CONDITIONING THERAPY IN NOCTURNAL ENURESIS. Dev Med Child Neurol. 1964 Apr;6:158–166. doi: 10.1111/j.1469-8749.1964.tb02775.x. [DOI] [PubMed] [Google Scholar]
  7. Glasziou P. P., Mackerras D. E. Vitamin A supplementation in infectious diseases: a meta-analysis. BMJ. 1993 Feb 6;306(6874):366–370. doi: 10.1136/bmj.306.6874.366. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Greenland S. Quantitative methods in the review of epidemiologic literature. Epidemiol Rev. 1987;9:1–30. doi: 10.1093/oxfordjournals.epirev.a036298. [DOI] [PubMed] [Google Scholar]
  9. Hatch M. C., Beyea J., Nieves J. W., Susser M. Cancer near the Three Mile Island nuclear plant: radiation emissions. Am J Epidemiol. 1990 Sep;132(3):397–417. doi: 10.1093/oxfordjournals.aje.a115673. [DOI] [PubMed] [Google Scholar]
  10. Hatch M. C., Wallenstein S., Beyea J., Nieves J. W., Susser M. Cancer rates after the Three Mile Island nuclear accident and proximity of residence to the plant. Am J Public Health. 1991 Jun;81(6):719–724. doi: 10.2105/ajph.81.6.719. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Hatch M., Susser M. Background gamma radiation and childhood cancers within ten miles of a US nuclear plant. Int J Epidemiol. 1990 Sep;19(3):546–552. doi: 10.1093/ije/19.3.546. [DOI] [PubMed] [Google Scholar]
  12. Jablon S., Hrubec Z., Boice J. D., Jr Cancer in populations living near nuclear facilities. A survey of mortality nationwide and incidence in two states. JAMA. 1991 Mar 20;265(11):1403–1408. [PubMed] [Google Scholar]
  13. Jones A. P., Friedman M. I. Obesity and adipocyte abnormalities in offspring of rats undernourished during pregnancy. Science. 1982 Mar 19;215(4539):1518–1519. doi: 10.1126/science.7063860. [DOI] [PubMed] [Google Scholar]
  14. Koopman J. S., Prevots D. R., Vaca Marin M. A., Gomez Dantes H., Zarate Aquino M. L., Longini I. M., Jr, Sepulveda Amor J. Determinants and predictors of dengue infection in Mexico. Am J Epidemiol. 1991 Jun 1;133(11):1168–1178. doi: 10.1093/oxfordjournals.aje.a115829. [DOI] [PubMed] [Google Scholar]
  15. Maclure M. Multivariate refutation of aetiological hypotheses in non-experimental epidemiology. Int J Epidemiol. 1990 Dec;19(4):782–787. doi: 10.1093/ije/19.4.782. [DOI] [PubMed] [Google Scholar]
  16. Milunsky A., Jick H., Jick S. S., Bruell C. L., MacLaughlin D. S., Rothman K. J., Willett W. Multivitamin/folic acid supplementation in early pregnancy reduces the prevalence of neural tube defects. JAMA. 1989 Nov 24;262(20):2847–2852. doi: 10.1001/jama.262.20.2847. [DOI] [PubMed] [Google Scholar]
  17. Paneth N., Kiely J. L., Wallenstein S., Marcus M., Pakter J., Susser M. Newborn intensive care and neonatal mortality in low-birth-weight infants: a population study. N Engl J Med. 1982 Jul 15;307(3):149–155. doi: 10.1056/NEJM198207153070303. [DOI] [PubMed] [Google Scholar]
  18. Piantadosi S., Byar D. P., Green S. B. The ecological fallacy. Am J Epidemiol. 1988 May;127(5):893–904. doi: 10.1093/oxfordjournals.aje.a114892. [DOI] [PubMed] [Google Scholar]
  19. Rose G. Sick individuals and sick populations. Int J Epidemiol. 1985 Mar;14(1):32–38. doi: 10.1093/ije/14.1.32. [DOI] [PubMed] [Google Scholar]
  20. Sommer A., Tarwotjo I., Djunaedi E., West K. P., Jr, Loeden A. A., Tilden R., Mele L. Impact of vitamin A supplementation on childhood mortality. A randomised controlled community trial. Lancet. 1986 May 24;1(8491):1169–1173. doi: 10.1016/s0140-6736(86)91157-8. [DOI] [PubMed] [Google Scholar]
  21. Susser E. S., Lin S. P. Schizophrenia after prenatal exposure to the Dutch Hunger Winter of 1944-1945. Arch Gen Psychiatry. 1992 Dec;49(12):983–988. doi: 10.1001/archpsyc.1992.01820120071010. [DOI] [PubMed] [Google Scholar]
  22. Susser M. Health as a human right: an epidemiologist's perspective on the public health. Am J Public Health. 1993 Mar;83(3):418–426. doi: 10.2105/ajph.83.3.418. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Susser M. Maternal weight gain, infant birth weight, and diet: causal sequences. Am J Clin Nutr. 1991 Jun;53(6):1384–1396. doi: 10.1093/ajcn/53.6.1384. [DOI] [PubMed] [Google Scholar]
  24. Susser M. The challenge of causality: human nutrition, brain development and mental performance. Bull N Y Acad Med. 1989 Dec;65(10):1032–1088. [PMC free article] [PubMed] [Google Scholar]
  25. Susser M. The logic in ecological: I. The logic of analysis. Am J Public Health. 1994 May;84(5):825–829. doi: 10.2105/ajph.84.5.825. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Susser M. What is a cause and how do we know one? A grammar for pragmatic epidemiology. Am J Epidemiol. 1991 Apr 1;133(7):635–648. doi: 10.1093/oxfordjournals.aje.a115939. [DOI] [PubMed] [Google Scholar]
  27. Unger C., Weiser J. K., McCullough R. E., Keefer S., Moore L. G. Altitude, low birth weight, and infant mortality in Colorado. JAMA. 1988 Jun 17;259(23):3427–3432. [PubMed] [Google Scholar]
  28. Yip R. Altitude and birth weight. J Pediatr. 1987 Dec;111(6 Pt 1):869–876. doi: 10.1016/s0022-3476(87)80209-3. [DOI] [PubMed] [Google Scholar]

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