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. 1995 Dec;85(12):1698–1702. doi: 10.2105/ajph.85.12.1698

Correlates of high-density lipoprotein cholesterol in Black girls and White girls: the NHLBI Growth and Health Study.

J A Simon 1, J A Morrison 1, S L Similo 1, R P McMahon 1, G B Schreiber 1
PMCID: PMC1615726  PMID: 7503349

Abstract

To determine the correlates of serum high-density lipoprotein cholesterol (HDL-C) in 9- and 10-year-old girls, data were examined from 624 Black girls and 773 White girls. Black girls had, on average, 3.6 mg/dL higher levels than White girls. Each 10-mm increase in sum of skinfolds was associated with a decrease of 1.4 mg/dL; each unit increase in the tricep/suprailiac skinfold ratio was associated with an increase of 2 mg/dL; and each 10% increase in polyunsaturated fat intake was associated with an increase of 3.4 mg/dL. The associations of sedentary activity and sexual maturation with HDL were mediated by differences in adiposity. Interventions to decrease adiposity may be important for the primary prevention of heart disease in women.

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Selected References

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  1. Bachorik P. S., Walker R. E., Virgil D. G. High-density-lipoprotein cholesterol in heparin-MnCl2 supernates determined with the Dow enzymic method after precipitation of Mn2+ with HCO3-. Clin Chem. 1984 Jun;30(6):839–842. [PubMed] [Google Scholar]
  2. Becker N., Illingworth D. R., Alaupovic P., Connor W. E., Sundberg E. E. Effects of saturated, monounsaturated, and omega-6 polyunsaturated fatty acids on plasma lipids, lipoproteins, and apoproteins in humans. Am J Clin Nutr. 1983 Mar;37(3):355–360. doi: 10.1093/ajcn/37.3.355. [DOI] [PubMed] [Google Scholar]
  3. Belcher J. D., Ellison R. C., Shepard W. E., Bigelow C., Webber L. S., Wilmore J. H., Parcel G. S., Zucker D. M., Luepker R. V. Lipid and lipoprotein distributions in children by ethnic group, gender, and geographic location--preliminary findings of the Child and Adolescent Trial for Cardiovascular Health (CATCH). Prev Med. 1993 Mar;22(2):143–153. doi: 10.1006/pmed.1993.1012. [DOI] [PubMed] [Google Scholar]
  4. Connett J. E., Stamler J. Responses of black and white males to the special intervention program of the Multiple Risk Factor Intervention Trial. Am Heart J. 1984 Sep;108(3 Pt 2):839–848. doi: 10.1016/0002-8703(84)90680-x. [DOI] [PubMed] [Google Scholar]
  5. Crawford P. B., Obarzanek E., Morrison J., Sabry Z. I. Comparative advantage of 3-day food records over 24-hour recall and 5-day food frequency validated by observation of 9- and 10-year-old girls. J Am Diet Assoc. 1994 Jun;94(6):626–630. doi: 10.1016/0002-8223(94)90158-9. [DOI] [PubMed] [Google Scholar]
  6. Croft J. B., Freedman D. S., Cresanta J. L., Srinivasan S. R., Burke G. L., Hunter S. M., Webber L. S., Smoak C. G., Berenson G. S. Adverse influences of alcohol, tobacco, and oral contraceptive use on cardiovascular risk factors during transition to adulthood. Am J Epidemiol. 1987 Aug;126(2):202–213. doi: 10.1093/aje/126.2.202. [DOI] [PubMed] [Google Scholar]
  7. Dietz W. H., Bandini L. G., Morelli J. A., Peers K. F., Ching P. L. Effect of sedentary activities on resting metabolic rate. Am J Clin Nutr. 1994 Mar;59(3):556–559. doi: 10.1093/ajcn/59.3.556. [DOI] [PubMed] [Google Scholar]
  8. Dietz W. H., Jr, Gortmaker S. L. Do we fatten our children at the television set? Obesity and television viewing in children and adolescents. Pediatrics. 1985 May;75(5):807–812. [PubMed] [Google Scholar]
  9. Dietz W. H. You are what you eat--what you eat is what you are. J Adolesc Health Care. 1990 Jan;11(1):76–81. doi: 10.1016/0197-0070(90)90133-m. [DOI] [PubMed] [Google Scholar]
  10. Donahue R. P., Orchard T. J., Kuller L. H., Drash A. L. Lipids and lipoproteins in a young adult population. The Beaver County Lipid Study. Am J Epidemiol. 1985 Sep;122(3):458–467. doi: 10.1093/oxfordjournals.aje.a114127. [DOI] [PubMed] [Google Scholar]
  11. Dreon D. M., Vranizan K. M., Krauss R. M., Austin M. A., Wood P. D. The effects of polyunsaturated fat vs monounsaturated fat on plasma lipoproteins. JAMA. 1990 May 9;263(18):2462–2466. [PubMed] [Google Scholar]
  12. Ford E., Cooper R., Simmons B., Katz S., Patel R. Sex differences in high density lipoprotein cholesterol in urban blacks. Am J Epidemiol. 1988 Apr;127(4):753–761. doi: 10.1093/oxfordjournals.aje.a114856. [DOI] [PubMed] [Google Scholar]
  13. Freedman D. S., Strogatz D. S., Eaker E., Joesoef M. R., DeStefano F. Differences between black and white men in correlates of high density lipoprotein cholesterol. Am J Epidemiol. 1990 Oct;132(4):656–669. doi: 10.1093/oxfordjournals.aje.a115707. [DOI] [PubMed] [Google Scholar]
  14. Freedman D. S., Strogatz D. S., Williamson D. F., Aubert R. E. Education, race, and high-density lipoprotein cholesterol among US adults. Am J Public Health. 1992 Jul;82(7):999–1006. doi: 10.2105/ajph.82.7.999. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Frerichs R. R., Webber L. S., Srinivasan S. R., Berenson G. S. Relation of serum lipids and lipoproteins to obesity and sexual maturity in white and black children. Am J Epidemiol. 1978 Dec;108(6):486–496. doi: 10.1093/oxfordjournals.aje.a112647. [DOI] [PubMed] [Google Scholar]
  16. Glueck C. J., Taylor H. L., Jacobs D., Morrison J. A., Beaglehole R., Williams O. D. Plasma high-density lipoprotein cholesterol: association with measurements of body mass. The Lipid Research Clinics Program Prevalence Study. Circulation. 1980 Nov;62(4 Pt 2):IV–62-9. [PubMed] [Google Scholar]
  17. Heath G. W., Macera C. A., Croft J. B., Mace M. L., Gillette T., Wheeler F. C. Correlates of high-density lipoprotein cholesterol in black and white women. Am J Public Health. 1994 Jan;84(1):98–101. doi: 10.2105/ajph.84.1.98. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Hegsted D. M., Ausman L. M., Johnson J. A., Dallal G. E. Dietary fat and serum lipids: an evaluation of the experimental data. Am J Clin Nutr. 1993 Jun;57(6):875–883. doi: 10.1093/ajcn/57.6.875. [DOI] [PubMed] [Google Scholar]
  19. Jackson R. L., Glueck C. J., Mathur S. N., Spector A. A. Effects of diet and high density lipoprotein subfractions on the removal of cellular cholesterol. Lipids. 1980 Apr;15(4):230–235. doi: 10.1007/BF02535832. [DOI] [PubMed] [Google Scholar]
  20. Kallio M. J., Salmenperä L., Siimes M. A., Perheentupa J., Miettinen T. A. Tracking of serum cholesterol and lipoprotein levels from the first year of life. Pediatrics. 1993 May;91(5):949–954. [PubMed] [Google Scholar]
  21. Khoury P. R., Morrison J. A., Laskarzewski P., Kelly K., Mellies M. J., King P., Larsen R., Glueck C. J. Relationships of education and occupation to coronary heart disease risk factors in school children and adults: the Princeton School District Study. Am J Epidemiol. 1981 Apr;113(4):378–395. doi: 10.1093/oxfordjournals.aje.a113106. [DOI] [PubMed] [Google Scholar]
  22. Linn S., Fulwood R., Rifkind B., Carroll M., Muesing R., Williams O. D., Johnson C. High density lipoprotein cholesterol levels among US adults by selected demographic and socioeconomic variables. The Second National Health and Nutrition Examination Survey 1976-1980. Am J Epidemiol. 1989 Feb;129(2):281–294. doi: 10.1093/oxfordjournals.aje.a115133. [DOI] [PubMed] [Google Scholar]
  23. Marti B., Suter E., Riesen W. F., Tschopp A., Wanner H. U. Anthropometric and lifestyle correlates of serum lipoprotein and apolipoprotein levels among normal non-smoking men and women. Atherosclerosis. 1989 Feb;75(2-3):111–122. doi: 10.1016/0021-9150(89)90167-6. [DOI] [PubMed] [Google Scholar]
  24. Mattson F. H., Grundy S. M. Comparison of effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on plasma lipids and lipoproteins in man. J Lipid Res. 1985 Feb;26(2):194–202. [PubMed] [Google Scholar]
  25. Mensink R. P., Katan M. B. Effect of dietary fatty acids on serum lipids and lipoproteins. A meta-analysis of 27 trials. Arterioscler Thromb. 1992 Aug;12(8):911–919. doi: 10.1161/01.atv.12.8.911. [DOI] [PubMed] [Google Scholar]
  26. Morrison J. A., Barton B., Biro F. M., Sprecher D. L., Falkner F., Obarzanek E. Sexual maturation and obesity in 9- and 10-year-old black and white girls: the National Heart, Lung, and Blood Institute Growth and Health Study. J Pediatr. 1994 Jun;124(6):889–895. doi: 10.1016/s0022-3476(05)83176-2. [DOI] [PubMed] [Google Scholar]
  27. Morrison J. A., Kelly K., Mellies M., deGroot I., Khoury P., Gartside P. S., Glueck C. J. Cigarette smoking, alcohol intake, and oral contraceptives: relationships to lipids and lipoproteins in adolescent school-children. Metabolism. 1979 Nov;28(11):1166–1170. doi: 10.1016/0026-0495(79)90157-4. [DOI] [PubMed] [Google Scholar]
  28. Morrison J. A., deGroot I., Edwards B. K., Kelly K. A., Mellies M. J., Khoury P., Glueck C. J. Lipids and lipoproteins in 927 schoolchildren, ages 6 to 17 years. Pediatrics. 1978 Dec;62(6):990–995. [PubMed] [Google Scholar]
  29. Morrison J. A., deGroot I., Kelly K. A., Mellies M. J., Khoury P., Lewis D., Lewis A., Fiorelli M., Tyroler H. A., Heiss G. Black--white differences in plasma lipoproteins in Cincinnati schoolchildren (one-to-one pair matched by total plasma cholesterol, sex, and age). Metabolism. 1979 Mar;28(3):241–245. doi: 10.1016/0026-0495(79)90070-2. [DOI] [PubMed] [Google Scholar]
  30. Obarzanek E., Schreiber G. B., Crawford P. B., Goldman S. R., Barrier P. M., Frederick M. M., Lakatos E. Energy intake and physical activity in relation to indexes of body fat: the National Heart, Lung, and Blood Institute Growth and Health Study. Am J Clin Nutr. 1994 Jul;60(1):15–22. doi: 10.1093/ajcn/60.1.15. [DOI] [PubMed] [Google Scholar]
  31. Porkka K. V., Viikari J. S., Akerblom H. K. Tracking of serum HDL-cholesterol and other lipids in children and adolescents: the Cardiovascular Risk in Young Finns Study. Prev Med. 1991 Nov;20(6):713–724. doi: 10.1016/0091-7435(91)90066-d. [DOI] [PubMed] [Google Scholar]
  32. Prewitt T. E., Haynes S. G., Graves K., Haines P. S., Tyroler H. A. Nutrient intake, lipids, and lipoprotein cholesterols in black and white children: the Lipid Research Clinics Prevalence Study. Prev Med. 1988 May;17(3):247–262. doi: 10.1016/0091-7435(88)90001-1. [DOI] [PubMed] [Google Scholar]
  33. Shepherd J., Packard C. J., Patsch J. R., Gotto A. M., Jr, Taunton O. D. Effects of dietary polyunsaturated and saturated fat on the properties of high density lipoproteins and the metabolism of apolipoprotein A-I. J Clin Invest. 1978 Jun;61(6):1582–1592. doi: 10.1172/JCI109078. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Srinivasan S. R., Frerichs R. R., Webber L. S., Berenson G. S. Serum lipoprotein profile in children from a biracial community: the Bogalusa Heart Study. Circulation. 1976 Aug;54(2):309–318. doi: 10.1161/01.cir.54.2.309. [DOI] [PubMed] [Google Scholar]
  35. Tyroler H. A., Hames C. G., Krishan I., Heyden S., Cooper G., Cassel J. C. Black-white differences in serum lipids and lipoproteins in Evans County. Prev Med. 1975 Dec;4(4):541–549. doi: 10.1016/0091-7435(75)90040-7. [DOI] [PubMed] [Google Scholar]
  36. Vega G. L., Groszek E., Wolf R., Grundy S. M. Influence of polyunsaturated fats on composition of plasma lipoproteins and apolipoproteins. J Lipid Res. 1982 Aug;23(6):811–822. [PubMed] [Google Scholar]
  37. Walter H. J., Hofman A. Socioeconomic status, ethnic origin, and risk factors for coronary heart disease in children. Am Heart J. 1987 Mar;113(3):812–818. doi: 10.1016/0002-8703(87)90724-1. [DOI] [PubMed] [Google Scholar]
  38. Watkins L. O., Neaton J. D., Kuller L. H. Racial differences in high-density lipoprotein cholesterol and coronary heart disease incidence in the usual-care group of the Multiple Risk Factor Intervention Trial. Am J Cardiol. 1986 Mar 1;57(8):538–545. doi: 10.1016/0002-9149(86)90831-3. [DOI] [PubMed] [Google Scholar]
  39. Webber L. S., Srinivasan S. R., Wattigney W. A., Berenson G. S. Tracking of serum lipids and lipoproteins from childhood to adulthood. The Bogalusa Heart Study. Am J Epidemiol. 1991 May 1;133(9):884–899. doi: 10.1093/oxfordjournals.aje.a115968. [DOI] [PubMed] [Google Scholar]
  40. Wilson P. W., Garrison R. J., Abbott R. D., Castelli W. P. Factors associated with lipoprotein cholesterol levels. The Framingham study. Arteriosclerosis. 1983 May-Jun;3(3):273–281. doi: 10.1161/01.atv.3.3.273. [DOI] [PubMed] [Google Scholar]

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