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. 1981 Nov;56(11):836–840. doi: 10.1136/adc.56.11.836

Behavioural effects of phenobarbitone and phenytoin in small children.

C J Bacon, J D Cranage, A M Hierons, M D Rawlins, J K Webb
PMCID: PMC1627392  PMID: 7305427

Abstract

Mothers of 56 children under 2 years old taking phenobarbitone and mothers of 55 children taking phenytoin recorded on questionnaires changes they had noted in the children's behaviour 3 and 9 weeks after starting the drug. Severe behavioural disturbance was noted by many, but the pattern and incidence was similar to that recorded by the mothers of 50 children starting a placebo, and we attribute it to the effect of a recent hospital admission. There was a small improvement in the behaviour of 20% of children who had been taking phenobarbitone for a year when they stopped it, but in this age group the disturbance caused by phenobarbitone did not appear to have been great.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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