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. 1984 Jan;59(1):7–12. doi: 10.1136/adc.59.1.7

Timing and evolution of periventricular haemorrhage in infants weighing 1250 g or less at birth.

W Szymonowicz, V Y Yu
PMCID: PMC1628438  PMID: 6696499

Abstract

The brains of 50 consecutively admitted infants who weighed 1250 g or less at birth were examined with real time ultrasound. Of 30 (60%) who had periventricular haemorrhage (PVH), 19 (63%) bled on the first day and 17 (57%) showed extension of the initial haemorrhage on serial scans. The median age was 16 hours when PVH was first detected and 48 hours when PVH reached its maximum extent. Ventricular size at birth correlated with gestation. Progressive ventricular growth was seen after birth in infants both with and without PVH. Charts of normal ranges of ventricular size and head circumference were drawn up from birth to 10 weeks of age. All infants with PVH showed a transient increase in ventricular size at 2 weeks of age but most returned to normal by 6 weeks of age. Ventricular dilatation after PVH that was greater than the 95th centile for this population developed in 5 (31%) of 16 survivors, four of whom subsequently developed hydrocephalus, although none required ventriculo peritoneal shunting. The optimal timing for diagnosis with ultrasound is at the end of the first week for PVH and the second to third week for ventricular dilatation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allan W. C., Holt P. J., Sawyer L. R., Tito A. M., Meade S. K. Ventricular dilation after neonatal periventricular-intraventricular hemorrhage. Natural history and therapeutic implications. Am J Dis Child. 1982 Jul;136(7):589–593. doi: 10.1001/archpedi.1982.03970430021006. [DOI] [PubMed] [Google Scholar]
  2. Clark C. E., Clyman R. I., Roth R. S., Sniderman S. H., Lane B., Ballard R. A. Risk factor analysis of intraventricular hemorrhage in low-birth-weight infants. J Pediatr. 1981 Oct;99(4):625–628. doi: 10.1016/s0022-3476(81)80276-4. [DOI] [PubMed] [Google Scholar]
  3. Cooke R. W. Factors associated with periventricular haemorrhage in very low birthweight infants. Arch Dis Child. 1981 Jun;56(6):425–431. doi: 10.1136/adc.56.6.425. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Donn S. M., Stuck K. J. Neonatal germinal matrix hemorrhage: evidence of a progressive lesion. J Pediatr. 1981 Sep;99(3):459–461. doi: 10.1016/s0022-3476(81)80349-6. [DOI] [PubMed] [Google Scholar]
  5. Dykes F. D., Lazzara A., Ahmann P., Blumenstein B., Schwartz J., Brann A. W. Intraventricular hemorrhage: a prospective evaluation of etiopathogenesis. Pediatrics. 1980 Jul;66(1):42–49. [PubMed] [Google Scholar]
  6. Hill A., Volpe J. J. Normal pressure hydrocephalus in the newborn. Pediatrics. 1981 Nov;68(5):623–629. [PubMed] [Google Scholar]
  7. Kosmetatos N., Dinter C., Williams M. L., Lourie H., Berne A. S. Intracranial hemorrhage in the premature. Its predictive features and outcome. Am J Dis Child. 1980 Sep;134(9):855–859. doi: 10.1001/archpedi.1980.02130210039011. [DOI] [PubMed] [Google Scholar]
  8. Levene M. I. Measurement of the growth of the lateral ventricles in preterm infants with real-time ultrasound. Arch Dis Child. 1981 Dec;56(12):900–904. doi: 10.1136/adc.56.12.900. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Levene M. I., Starte D. R. A longitudinal study of post-haemorrhagic ventricular dilatation in the newborn. Arch Dis Child. 1981 Dec;56(12):905–910. doi: 10.1136/adc.56.12.905. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Levene M. I., Wigglesworth J. S., Dubowitz V. Cerebral structure and intraventricular haemorrhage in the neonate: a real-time ultrasound study. Arch Dis Child. 1981 Jun;56(6):416–424. doi: 10.1136/adc.56.6.416. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Mantovani J. F., Pasternak J. F., Mathew O. P., Allan W. C., Mills M. T., Casper J., Volpe J. J. Failure of daily lumbar punctures to prevent the development of hydrocephalus following intraventricular hemorrhage. J Pediatr. 1980 Aug;97(2):278–281. doi: 10.1016/s0022-3476(80)80495-1. [DOI] [PubMed] [Google Scholar]
  12. Marks K. H., Maisels M. J., Moore E., Gifford K., Friedman Z. Head growth in sick premature infants--a longitudinal study. J Pediatr. 1979 Feb;94(2):282–285. doi: 10.1016/s0022-3476(79)80844-6. [DOI] [PubMed] [Google Scholar]
  13. Pape K. E., Bennett-Britton S., Szymonowicz W., Martin D. J., Fitz C. R., Becker L. Diagnostic accuracy of neonatal brain imaging: a postmortem correlation of computed tomography and ultrasound scans. J Pediatr. 1983 Feb;102(2):275–280. doi: 10.1016/s0022-3476(83)80543-5. [DOI] [PubMed] [Google Scholar]
  14. Papile L. A., Burstein J., Burstein R., Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr. 1978 Apr;92(4):529–534. doi: 10.1016/s0022-3476(78)80282-0. [DOI] [PubMed] [Google Scholar]
  15. Papile L. A., Burstein J., Burstein R., Koffler H., Koops B. L., Johnson J. D. Posthemorrhagic hydrocephalus in low-birth-weight infants: treatment by serial lumbar punctures. J Pediatr. 1980 Aug;97(2):273–277. doi: 10.1016/s0022-3476(80)80494-x. [DOI] [PubMed] [Google Scholar]
  16. Partridge J. C., Babcock D. S., Steichen J. J., Han B. K. Optimal timing for diagnostic cranial ultrasound in low-birth-weight infants: detection of intracranial hemorrhage and ventricular dilation. J Pediatr. 1983 Feb;102(2):281–287. doi: 10.1016/s0022-3476(83)80544-7. [DOI] [PubMed] [Google Scholar]
  17. Sauerbrei E. E., Digney M., Harrison P. B., Cooperberg P. L. Ultrasonic evaluation of neonatal intracranial hemorrhage and its complications. Radiology. 1981 Jun;139(3):677–685. doi: 10.1148/radiology.139.3.7232735. [DOI] [PubMed] [Google Scholar]
  18. Simpson H. C., Simpson R. W., Lousley S., Carter R. D., Geekie M., Hockaday T. D., Mann J. I. A high carbohydrate leguminous fibre diet improves all aspects of diabetic control. Lancet. 1981 Jan 3;1(8210):1–5. doi: 10.1016/s0140-6736(81)90112-4. [DOI] [PubMed] [Google Scholar]
  19. Thorburn R. J., Lipscomb A. P., Stewart A. L., Reynolds E. O., Hope P. L. Timing and antecedents of periventricular haemorrhage and of cerebral atrophy in very preterm infants. Early Hum Dev. 1982 Dec 6;7(3):221–238. doi: 10.1016/0378-3782(82)90085-8. [DOI] [PubMed] [Google Scholar]
  20. Volpe J. J., Pasternak J. F., Allan W. C. Ventricular dilation preceding rapid head growth following neonatal intracranial hemorrhage. Am J Dis Child. 1977 Nov;131(11):1212–1215. doi: 10.1001/archpedi.1977.02120240030006. [DOI] [PubMed] [Google Scholar]
  21. Williams J., Hirsch N. J., Corbet A. J., Rudolph A. J. Postnatal head shrinkage in small infants. Pediatrics. 1977 Apr;59(4):619–622. [PubMed] [Google Scholar]
  22. de Crespigny L. C., Mackay R., Murton L. J., Roy R. N., Robinson P. H. Timing of neonatal cerebroventricular haemorrhage with ultrasound. Arch Dis Child. 1982 Mar;57(3):231–233. doi: 10.1136/adc.57.3.231. [DOI] [PMC free article] [PubMed] [Google Scholar]

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