Abstract
We examined the plasma urea and creatinine concentrations and the ratio between them according to diagnosis in 100 unselected and 31 selected adult hospital patients with a plasma urea concentration greater than or equal to 10 mmol/l (60mg/100ml). We also examined plasma urea and creatinine concentrations in 350 unselected consecutive patients, but found no useful relation between the two values. Congestive heart failure was the most common identifiable cause of a raised plasma urea concentration in the 100 unselected patients (36%). Among these 100 patinets the plasma creatinine concentration was a more useful discriminant between prerenal uraemia and intrinsic renal failure than was the urea:creatinine ratio or the plasma urea concentration. A plasma creatinine concentration greater than 250 mumol/1 (2-8 mg/100ml) indicated intrinsic renal failure with a 90% probability.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BLUMGART H. L., ZOLL P. M. The clinical management of congestive heart failure. Circulation. 1960 Feb;21:218–228. doi: 10.1161/01.cir.21.2.218. [DOI] [PubMed] [Google Scholar]
- Baum N., Dichoso C. C., Carlton C. E. Blood urea nitrogen and serum creatinine. Physiology and interpretations. Urology. 1975 May;5(5):583–588. doi: 10.1016/0090-4295(75)90105-3. [DOI] [PubMed] [Google Scholar]
- Domenet J. G., Evans D. W. Uraemia in congestive heart failure. Q J Med. 1969 Jan;38(149):117–133. [PubMed] [Google Scholar]
- Dossetor J. B. Creatininemia versus uremia. The relative significance of blood urea nitrogen and serum creatinine concentrations in azotemia. Ann Intern Med. 1966 Dec;65(6):1287–1299. doi: 10.7326/0003-4819-65-6-1287. [DOI] [PubMed] [Google Scholar]
- GOODYER A. V. Renal function and renal impairment in congestive heart failure. Prog Cardiovasc Dis. 1961 Mar;3:483–500. doi: 10.1016/s0033-0620(61)80005-4. [DOI] [PubMed] [Google Scholar]
- Kahn S., Sagel J., Eales L., Rabkin R. The significance of serum creatinine and the blood urea-serum creatinine ratio in azotaemia. S Afr Med J. 1972 Nov 25;46(47):1828–1832. [PubMed] [Google Scholar]
- THAYER J. M. Renal abnormalities in congestive heart failure. Stanford Med Bull. 1960 Aug;18:129–137. [PubMed] [Google Scholar]
- Ujjwal J. S., Bhatnagar H. N., Bordia A. Uraemia in congestive heart failure. J Assoc Physicians India. 1974 Aug;22(8):589–596. [PubMed] [Google Scholar]