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. 1976 Jan 24;1(6003):186–188. doi: 10.1136/bmj.1.6003.186

Intestinal absorption in normal Indian and English people.

M D Hellier, A N Radhakrishnan, V Ganapathy, A Gammon, S J Baker
PMCID: PMC1638486  PMID: 1247768

Abstract

The absorption of glycine, glycylglycine, water, and electrolytes was studied by intestinal perfusion in normal Indian and English people. Compared with the English people the Indians showed impaired absorption of all four substances. In the Indians the absorption of glycine and glycylglycine was impaired to the same extent, so that the kinetic advantage of glycylglycine as compared with glycine was preserved. The reduced absorption in the Indians may be the functional counterpart of the minor morphological changes seen in the jejunal mucosa of people living in southern India.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baker S. J. Geographical variations in the morphology of the small intestinal mucosa in apparently healthy individuals. Pathol Microbiol (Basel) 1973;39(3):222–237. doi: 10.1159/000162651. [DOI] [PubMed] [Google Scholar]
  2. Baker S. J., Jacob R., Mathan V. I. An evaluation of the 5 g D-xylose absorption test, with fractional urine collections, in subjects living in Southern India. Indian J Med Res. 1971 Dec;59(12):1869–1877. [PubMed] [Google Scholar]
  3. Baker S. J., Mathan V. I. Tropical enteropathy and tropical sprue. Am J Clin Nutr. 1972 Oct;25(10):1047–1055. doi: 10.1093/ajcn/25.10.1047. [DOI] [PubMed] [Google Scholar]
  4. Bhat P., Shantakumari S., Rajan D., Mathan V. I., Kapadia C. R., Swarnabai C., Baker S. J. Bacterial flora of the gastrointestinal tract in southern Indian control subjects and patients with tropical sprue. Gastroenterology. 1972 Jan;62(1):11–21. [PubMed] [Google Scholar]
  5. Das M., Radhakrishnan A. N. Glycyl-L-leucine hydrolase, a versatile 'master' dipeptidase from monkey small intestine. Biochem J. 1973 Dec;135(4):609–615. doi: 10.1042/bj1350609. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. GOUGH K. R., READ A. E., MCCARTHY C. F., WATERS A. H. MEGALOBLASTIC ANAEMIA DUE TO NUTRITIONAL DEFICIENCY OF FOLIC ACID. Q J Med. 1963 Jul;32:243–256. [PubMed] [Google Scholar]
  7. Hellier M. D., Holdsworth C. D., McColl I., Perrett D. Dipeptide absorption in man. Gut. 1972 Dec;13(12):965–969. doi: 10.1136/gut.13.12.965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Jensen H., Jarnum S., Hart Hansen J. P. Gastrointestinal protein loss and intestinal function in the nephrotic syndrome. Nephron. 1966;3(4):209–220. doi: 10.1159/000179536. [DOI] [PubMed] [Google Scholar]
  9. Mathan M., Mathan V. I., Swaminathan S. P., Yesudoss S. Pleomorphic virus-like particles in human faeces. Lancet. 1975 May 10;1(7915):1068–1069. doi: 10.1016/S0140-6736(75)91832-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Mathan V. I., Swarnabai S., Baker S. J. Intestinal absorption of radioactive vitamin B 12: a comparison of plasma, faecal and urinary tests. Indian J Med Res. 1973 May;61(5):714–723. [PubMed] [Google Scholar]
  11. Swaminathan N., Mathan V. I., Baker S. J., Radhakrishnan A. N. Disaccharidase levels in jejunal biopsy specimens from American and south Indian control subjects and patients with tropical sprue. Clin Chim Acta. 1970 Dec;30(3):707–712. doi: 10.1016/0009-8981(70)90264-0. [DOI] [PubMed] [Google Scholar]

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