Abstract
A total of 141 cases of hypothyroidism diagnosed within the first two years has been reviewed. The best mental development was achieved when treatment was begun within the first three months of life. At this time hypothyroidism presents mainly with symptoms—usually feeding difficulty, constipation, and lethargy, while the classical physical signs are less obvious than later.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- CRANEFIELD P. F. The discovery of cretinism. Bull Hist Med. 1962 Nov-Dec;36:489–511. [PubMed] [Google Scholar]
- FEDERMAN D., ROBBINS J., RALL J. E. Some observations on cretinism and its treatment. N Engl J Med. 1958 Sep 25;259(13):610–615. doi: 10.1056/NEJM195809252591302. [DOI] [PubMed] [Google Scholar]
- LOWREY G. H., ASTER R. H., CARR E. A., RAMON G., BEIERWALTES W. H., SPAFFORD N. R. Early diagnostic criteria of congenital hypothyroidism: a comprehensive study of forty-nine cretins. AMA J Dis Child. 1958 Aug;96(2):131–143. doi: 10.1001/archpedi.1958.02060060133002. [DOI] [PubMed] [Google Scholar]
- MAN E. B., MERMANN A. C., COOKE R. E. THE DEVELOPMENT OF CHILDREN WITH CONGENITAL HYPOTHYROIDISM. A NOTE ON EARLY, TEMPORARY REPLACEMENT THERAPY FOR 2 GOITROUS INFANTS. J Pediatr. 1963 Nov;63:926–941. doi: 10.1016/s0022-3476(63)80223-1. [DOI] [PubMed] [Google Scholar]
- PICKERING D. E., FISHER D. A. Therapeutic concepts relating to hypothyroidism in childhood. J Chronic Dis. 1958 Mar;7(3):242–263. doi: 10.1016/0021-9681(58)90030-4. [DOI] [PubMed] [Google Scholar]
- Raiti S., Holzman G. B., Scott R. L., Blizzard R. M. Evidence for the placental transfer of tri-iodothyronine in human beings. N Engl J Med. 1967 Aug 31;277(9):456–459. doi: 10.1056/NEJM196708312770903. [DOI] [PubMed] [Google Scholar]
- SABEH G., SARVER M. E., MOSES C., DANOWSKI T. S. TRIIODOTHYRONINE BINDING TO RED BLOOD CELLS AND ACHILLES TENDON REFLEX AS THYROID INDICES. Am J Med Sci. 1964 Sep;248:253–259. doi: 10.1097/00000441-196409000-00001. [DOI] [PubMed] [Google Scholar]
- SMITH D. W., BLIZZARD R. M., WILKINS L. The mental prognosis in hypothyroidism of infancy and childhood; a review of 128 cases. Pediatrics. 1957 Jun;19(6):1011–1022. [PubMed] [Google Scholar]