Skip to main content
PMC home page
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1972 Oct;47(255):688–696. doi: 10.1136/adc.47.255.688

Duodenal Ulcer in Children

J D A Robb, P S Thomas, J Orszulok, G W Odling-Smee
PMCID: PMC1648201  PMID: 5086503

Abstract

Forty-nine cases of duodenal ulcer in children are presented. Strict radiological and clinical criteria were observed in making this diagnosis. The children came from a population of approximately 100,000 children over a 10-year period. Upper abdominal pain was the commonest presenting symptom, and exacerbations and remissions of the disease were observed to be shorter than is expected in the adult. Haemorrhage occurred as a complication in 24% and there were no cases of perforation or stenosis. A family history of duodenal ulcer was found to be highly significant, and it was found that in 55% of patients there was an important element of stress.

Treatment was conservative in all but 2 cases, in both of which a vagotomy and pyloroplasty were performed. These operations were judged to have been successful. 6 cases had appendicectomy in the hope of relieving undiagnosed abdominal pain, in which it was unsuccessful. A plea is made for keeping this diagnosis in mind when dealing with abdominal pain in children.

Full text

PDF
690

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AIRD I., BENTALL H. H., MEHIGAN J. A., ROBERTS J. A. F. The blood groups in relation to peptic ulceration and carcinoma of colon, rectum, breast, and bronchus; an association between the ABO groups and peptic ulceration. Br Med J. 1954 Aug 7;2(4883):315–321. doi: 10.1136/bmj.2.4883.315. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. ALEXANDER F. K. Duodenal ulcer in children. Radiology. 1951 Jun;56(6):799–812. doi: 10.1148/56.6.799. [DOI] [PubMed] [Google Scholar]
  3. BOLEY S. J., KRIEGER H., SCHWARTZ S., HARANDIAN B., PEARLMAN B. THE EFFECT OF OPERATIONS FOR PEPTIC ULCER ON GROWTH AND NUTRITION OF PUPPIES. Surgery. 1965 Mar;57:441–447. [PubMed] [Google Scholar]
  4. Bird C. E., Limper M. A., Mayer J. M. SURGERY IN PEPTIC ULCERATION OF STOMACH AND DUODENUM IN INFANTS AND CHILDREN. Ann Surg. 1941 Oct;114(4):526–542. doi: 10.1097/00000658-194110000-00004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Dodge J. A. ABO blood groups and infantile hypertrophic pyloric stenosis. Br Med J. 1967 Dec 30;4(5582):781–782. doi: 10.1136/bmj.4.5582.781. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Dodge J. A. Production of duodenal ulcers and hypertrophic pyloric stenosis by administration of pentagastrin to pregnant and newborn dogs. Nature. 1970 Jan 17;225(5229):284–285. doi: 10.1038/225284a0. [DOI] [PubMed] [Google Scholar]
  7. Dogan K., Oberiter V., Najman E., Dogan S., Buneta L., Rudar D., Mark B. Neke osobitosti zelucanog i duodenalnog ulkusa u djecjoj dobi. Lijec Vjesn. 1969;91(10):1045–1058. [PubMed] [Google Scholar]
  8. Emås S., Lilja B., Borg I. Comparison ofthe effect of histamine and pentagastrin on gastric secretion in ulcer patients. Scand J Gastroenterol. 1969;4(2):151–156. doi: 10.3109/00365526909179923. [DOI] [PubMed] [Google Scholar]
  9. FALLSTROM S. P., REINAND T. Peptic ulcer in children. Acta Paediatr. 1961 Jul;50:431–436. doi: 10.1111/j.1651-2227.1961.tb08197.x. [DOI] [PubMed] [Google Scholar]
  10. GHAI O. P., SINGH M., WALIA B. N., GADEKAR N. G. AN ASSESSMENT OF GASTRIC ACID SECRETORY RESPONSE WITH 'MAXIMAL' AUGMENTED HISTAMINE STIMULATION IN CHILDREN WITH PEPTIC ULCER. Arch Dis Child. 1965 Feb;40:77–79. doi: 10.1136/adc.40.209.77. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. GOLDBERG H. M. Duodenal ulcers in children. Br Med J. 1957 Jun 29;1(5034):1500–1502. doi: 10.1136/bmj.1.5034.1500. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Guthorn P. J., De Spirito A. P., Raffetto J. E., Parkhill U. A. Bleeding neonatal duodenal ulcer. Successful surgical treatment of two cases. J Med Soc N J. 1970 Mar;67(3):125–127. [PubMed] [Google Scholar]
  13. Habbick B. F., Melrose A. G., Grant J. C. Duodenal ulcer in childhood. A study of predisposing factors. Arch Dis Child. 1968 Feb;43(227):23–27. doi: 10.1136/adc.43.227.23. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Johnston P. W., Snyder W. H., Jr Vagotomy and pyloroplasty in infancy and childhood. J Pediatr Surg. 1968 Apr;3(2):238–245. doi: 10.1016/0022-3468(68)90006-7. [DOI] [PubMed] [Google Scholar]
  15. MACAFEE A. L. BLOOD GROUPS AND DIABETES MELLITUS. J Clin Pathol. 1964 Jan;17:39–41. doi: 10.1136/jcp.17.1.39. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. MCALEESE J. J., SIEBER W. K. The surgical problem presented by peptic ulcer of the stomach and duodenum in infancy and childhood. Ann Surg. 1953 Mar;137(3):334–341. doi: 10.1097/00000658-195303000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. MICHENER W. M., KENNEDY R. L., DUSHANE J. W. Duodenal ulcer in childhood. Ninety-two cases with follow-up. Am J Dis Child. 1960 Dec;100:814–817. doi: 10.1001/archpedi.1960.04020040816003. [DOI] [PubMed] [Google Scholar]
  18. MILLIKEN J. C. DUODENAL ULCERATION IN CHILDREN. Gut. 1965 Feb;6:25–28. doi: 10.1136/gut.6.1.25. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Oi I., Takemoto T., Nakayama K. "Fiberduodenoscopy"--early diagnosis of cancer of the papilla of Vater. Surgery. 1970 Apr;67(4):561–565. [PubMed] [Google Scholar]
  20. Proscia N., Sorisio F. Perforazione di ulcera duodenale in n neonato. Minerva Chir. 1968 Jul 15;23(13):695–698. [PubMed] [Google Scholar]
  21. Raffensperger J. G., Condon J. B., Greengard J. Complications of gastric and duodenal ulcers in infancy and childhood. Surg Gynecol Obstet. 1966 Dec;123(6):1269–1274. [PubMed] [Google Scholar]
  22. Ravitch M. M. Duodenal ulcer in childhood. Med Times. 1969 Jul;97(7):196–198. [PubMed] [Google Scholar]
  23. Ravitch M. M., Duremides G. D. Operative treatment of chronic duodenal ulcer in childhood. Ann Surg. 1970 May;171(5):641–646. doi: 10.1097/00000658-197005000-00002. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Rodbro P., Krasilnikoff P., Christiansen P. M., Bitsch V. Gastric secretion in early childhood. Lancet. 1966 Oct 1;2(7466):730–731. doi: 10.1016/s0140-6736(66)92984-9. [DOI] [PubMed] [Google Scholar]
  25. Rosenlund M. L., Koop C. E. Duodenal ulcer in childhood. Pediatrics. 1970 Feb;45(2):283–286. [PubMed] [Google Scholar]
  26. SCHUSTER S. R., GROSS R. E. Peptic ulcer disease in childhood. Am J Surg. 1963 Mar;105:324–333. doi: 10.1016/0002-9610(63)90344-1. [DOI] [PubMed] [Google Scholar]
  27. STEIN G. N., MARTIN R. D., ROY R. H., FINKELSTEIN A. K. EVALUATION OF CONVENTIONAL ROENTGENOGRAPHIC TECHNIQUES FOR DEMONSTRATION OF DUODENAL ULCER CRATERS. Am J Roentgenol Radium Ther Nucl Med. 1964 Apr;91:801–807. [PubMed] [Google Scholar]
  28. Singh M., Ghai O. P. Duodenal ulcer in childhood: A clinical and psychological study. Indian Pediatr. 1969 Jul;6(7):447–452. [PubMed] [Google Scholar]
  29. Solanke T. F., Antia A. U. Peptic ulcer in Nigerian children. West Afr Med J Niger Pract. 1968 Aug;17(4):110–114. [PubMed] [Google Scholar]
  30. Tryfabiv A. Ia. Nekotorye osobennosti techeniia iazvennoi bolezni v molodom vozraste. Vrach Delo. 1967 Oct;10:116–118. [PubMed] [Google Scholar]
  31. Tudor R. B. Peptic ulcerations in childhood. Pediatr Clin North Am. 1967 Feb;14(1):109–139. doi: 10.1016/s0031-3955(16)31946-0. [DOI] [PubMed] [Google Scholar]
  32. Zudov G. V. Dve probodnye iazvy dvenadtsatiperstnoi kishki u mal'chika 8 let. Khirurgiia (Mosk) 1968 Jul;44(7):138–138. [PubMed] [Google Scholar]
  33. van Benthem L. H., Hian T. W. Het ulcus pepticum op de kinderleeftijd. Ned Tijdschr Geneeskd. 1969 Jul 26;113(30):1310–1314. [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES