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. 1972 Oct;46(2):355–357. doi: 10.1111/j.1476-5381.1972.tb06882.x

The removal of 14C-edrophonium from the circulation

D J Back, T N Calvey
PMCID: PMC1666356  PMID: 4651777

Abstract

The clearance of 14C-edrophonium from plasma was studied in the rat. Distribution studies showed that 5 min after intravenous injection of the drug, more than half the dose was present in the liver and the kidneys. The concentration in these organs was approximately 20 times the level in other tissues. The plasma concentration of 14C-edrophonium was invariably expressed as the sum of two exponential terms, suggesting that the drug may return to the circulation from other tissues as the plasma level falls.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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