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. 1971 Jun;42(2):311–313. doi: 10.1111/j.1476-5381.1971.tb07115.x

Further studies on the effect of ageing on β-adrenoceptor activity of rat aorta

J H Fleisch
PMCID: PMC1667170  PMID: 5091166

Abstract

β-Adrenoceptor activity of rat thoracic aorta decreased with the increasing age of the animal. The ability of aortas to relax to isoprenaline was completely lost when rats were 3-6 months old, depending on the source and strain of animals. NaNO2, however, completely relaxed aortic tissue from animals of all ages tested.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. FURCHGOTT R. F., BHADRAKOM S. Reactions of strips of rabbit aorta to epinephrine, isopropylarterenol, sodium nitrite and other drugs. J Pharmacol Exp Ther. 1953 Jun;108(2):129–143. [PubMed] [Google Scholar]
  2. Fleisch J. H., Maling H. M., Brodie B. B. Beta-receptor activity in aorta; variations with age and species. Circ Res. 1970 Feb;26(2):151–162. doi: 10.1161/01.res.26.2.151. [DOI] [PubMed] [Google Scholar]

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