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. 1977 Aug;60(4):481–497. doi: 10.1111/j.1476-5381.1977.tb07526.x

Sixth gaddum memorial lecture, National Institute for Medical Research, Mill Hill, January 1977. Presynaptic receptors and their role in the regulation of transmitter release.

S Z Langer
PMCID: PMC1667392  PMID: 20190

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Selected References

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  1. AMIN A. H., CRAWFORD T. B., GADDUM J. H. The distribution of substance P and 5-hydroxytryptamine in the central nervous system of the dog. J Physiol. 1954 Dec 10;126(3):596–618. doi: 10.1113/jphysiol.1954.sp005229. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Adler-Graschinsky E., Langer S. Z. Possible role of a beta-adrenoceptor in the regulation of noradrenaline release by nerve stimulation through a positive feed-back mechanism. Br J Pharmacol. 1975 Jan;53(1):43–50. doi: 10.1111/j.1476-5381.1975.tb07328.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Andén N. E., Grabowska M., Strömbom U. Different alpha-adrenoreceptors in the central nervous system mediating biochemical and functional effects of clonidine and receptor blocking agents. Naunyn Schmiedebergs Arch Pharmacol. 1976;292(1):43–52. doi: 10.1007/BF00506488. [DOI] [PubMed] [Google Scholar]
  4. Armstrong J. M., Boura A. L. Effects of clonidine and guanethidine on peripheral sympathetic nerve function in the pithed rat. Br J Pharmacol. 1973 Apr;47(4):850–852. doi: 10.1111/j.1476-5381.1973.tb08214.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. BLAKELEY A. G., BROWN G. L., FERRY C. B. Pharmacological experiments on the release of the sympathetic transmitter. J Physiol. 1963 Jul;167:505–514. doi: 10.1113/jphysiol.1963.sp007165. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. BROWN G. L., GILLESPIE J. S. The output of sympathetic transmitter from the spleen of the cat. J Physiol. 1957 Aug 29;138(1):81–102. doi: 10.1113/jphysiol.1957.sp005839. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Barrett A. M., Nunn B. Adrenergic neuron blocking properties of (plus or minus)-propranolol and (plus)-propranolol. J Pharm Pharmacol. 1970 Nov;22(11):806–810. doi: 10.1111/j.2042-7158.1970.tb08443.x. [DOI] [PubMed] [Google Scholar]
  8. Boullin D. J., Costa E., Brodie B. B. Evidence that blockade of adrenergic receptors causes overflow of norepinephrine in cats colon after nerve stimulation. J Pharmacol Exp Ther. 1967 Jul;157(1):125–134. [PubMed] [Google Scholar]
  9. Chang H. C., Gaddum J. H. Choline esters in tissue extracts. J Physiol. 1933 Oct 6;79(3):255–285. doi: 10.1113/jphysiol.1933.sp003049. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Cubeddu L., 5th, Barnes E., Weiner N. Release of norepinephrine and dopamine-beta-hydroxylase by nerve stimulation. IV. An evaluation of a role for cyclic adenosine monophosphate. J Pharmacol Exp Ther. 1975 Apr;193(1):105–127. [PubMed] [Google Scholar]
  11. Cubeddu L., Barnes E. M., Langer S. Z., Weiner N. Release of norepinephrine and dopamine-beta-hydroxylase by nerve stimulation. I. Role of neuronal and extraneuronal uptake and of alpha presynaptic receptors. J Pharmacol Exp Ther. 1974 Sep;190(3):431–450. [PubMed] [Google Scholar]
  12. Cubeddu L., Weiner N. Nerve stimulation-meditated overflow of norepinephrine and dopamine-beta-hydroxylase. III. Effects of norepinephrine depletion on the alpha presynaptic regulation of release. J Pharmacol Exp Ther. 1975 Jan;192(1):1–14. [PubMed] [Google Scholar]
  13. De Potter W. P., Chubb I. W., Put A., De Schaepdryver A. F. Facilitation of the release of noradrenaline and dopamine- -hydroxylase at low stimulation frequencies by -blocking agents. Arch Int Pharmacodyn Ther. 1971 Sep;193(1):191–197. [PubMed] [Google Scholar]
  14. Dismukes R. K., Mulder A. H. Cyclic AMP and alpha-receptor-mediated modulation of noradrenaling release from rat brain slices. Eur J Pharmacol. 1976 Oct;39(2):383–388. doi: 10.1016/0014-2999(76)90148-5. [DOI] [PubMed] [Google Scholar]
  15. Dubocovich M. L., Langer S. Z. Evidence against a physiological role of prostaglandins in the regulation of noradrenaline release in the cat spleen. J Physiol. 1975 Oct;251(3):737–762. doi: 10.1113/jphysiol.1975.sp011119. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Dubocovich M. L., Langer S. Z. Influence of the frequency of nerve stimulation on the metabolism of 3H-norepinephrine released from the perfused cat spleen: differences observed during and after the period of stimulation. J Pharmacol Exp Ther. 1976 Jul;198(1):83–101. [PubMed] [Google Scholar]
  17. Dubocovich M. L., Langer S. Z. Negative feed-back regulation of noradrenaline release by nerve stimulation in the perfused cat's spleen: differences in potency of phenoxybenzamine in blocking the pre- and post-synaptic adrenergic receptors. J Physiol. 1974 Mar;237(3):505–519. doi: 10.1113/jphysiol.1974.sp010495. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Dubocovich M., Langer S. Z. Effects of flow-stop on the metabolism of noradrenaline released by nerve stimulation in the perfused spleen. Naunyn Schmiedebergs Arch Pharmacol. 1973;278(2):179–194. doi: 10.1007/BF00500649. [DOI] [PubMed] [Google Scholar]
  19. Eisenfeld A. J., Axelrod J., Krakoff L. Inhibition of the extraneuronal accumulation and metabolism of norepinephrine by adrenergic blocking agents. J Pharmacol Exp Ther. 1967 Apr;156(1):107–113. [PubMed] [Google Scholar]
  20. Enero M. A., Langer S. Z. Influence of reserpine-induced depletion of noradrenaline on the negative feed-back mechanism for transmitter release during nerve stimulation. Br J Pharmacol. 1973 Oct;49(2):214–225. doi: 10.1111/j.1476-5381.1973.tb08367.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Enero M. A., Langer S. Z. Inhibition by dopamine of 3H-noradrenaline release elicited by nerve stimulation in the isolated cat's nictitating membrane. Naunyn Schmiedebergs Arch Pharmacol. 1975;289(2):179–203. doi: 10.1007/BF00501305. [DOI] [PubMed] [Google Scholar]
  22. Enero M. A., Langer S. Z., Rothlin R. P., Stefano F. J. Role of the -adrenoceptor in regulating noradrenaline overflow by nerve stimulation. Br J Pharmacol. 1972 Apr;44(4):672–688. doi: 10.1111/j.1476-5381.1972.tb07306.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Farah M. B., Langer S. Z. Protection by phentolamine against the effects of phenoxybenzamine on transmitter release elicited by nerve stimulation in the perfused cat heart. Br J Pharmacol. 1974 Dec;52(4):549–557. doi: 10.1111/j.1476-5381.1974.tb09723.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Farnebo L. O., Hamberger B. Drug-induced changes in the release of ( 3 H)-noradrenaline from field stimulated rat iris. Br J Pharmacol. 1971 Sep;43(1):97–106. doi: 10.1111/j.1476-5381.1971.tb07160.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Farnebo L. O., Hamberger B. Drug-induced changes in the release of 3 H-monoamines from field stimulated rat brain slices. Acta Physiol Scand Suppl. 1971;371:35–44. doi: 10.1111/j.1748-1716.1971.tb05213.x. [DOI] [PubMed] [Google Scholar]
  26. Farnebo L. O., Malamfors T. 3 H-noradrenaline release and mechanical response in the field stimulated mouse vas deferens. Acta Physiol Scand Suppl. 1971;371:1–18. doi: 10.1111/j.1748-1716.1971.tb05210.x. [DOI] [PubMed] [Google Scholar]
  27. Feldberg W., Gaddum J. H. The chemical transmitter at synapses in a sympathetic ganglion. J Physiol. 1934 Jun 9;81(3):305–319. doi: 10.1113/jphysiol.1934.sp003137. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Gaddum J. H., Jang C. S., Kwiatkowski H. The effect on the intestine of the substance liberated by adrenergic nerves in a rabbit's ear. J Physiol. 1939 Jun 14;96(1):104–108. doi: 10.1113/jphysiol.1939.sp003760. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Gaddum J. H., Peart W. S., Vogt M. The estimation of adrenaline and allied substances in blood. J Physiol. 1949 Jun 15;108(4):467–481. doi: 10.1113/jphysiol.1949.sp004350. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Haefely W., Hürlimann A., Thoenen H. Relation between the rate of stimulation and the quantity of noradrenaline liberated from sympathetic nerve endings in the isolated perfused spleen of the cat. J Physiol. 1965 Nov;181(1):48–58. doi: 10.1113/jphysiol.1965.sp007744. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Haeusler G. Clonidine-induced inhibition of sympathetic nerve activity: no indication for a central presynaptic or an indirect sympathomimetic mode of action. Naunyn Schmiedebergs Arch Pharmacol. 1974;286(1):07–111. doi: 10.1007/BF00499107. [DOI] [PubMed] [Google Scholar]
  32. Hedqvist P. Antagonism by calcium of the inhibitory action of prostaglandin E2 on sympathetic neurotransmission in the cat spleen. Acta Physiol Scand. 1970 Oct;80(2):269–275. doi: 10.1111/j.1748-1716.1970.tb04790.x. [DOI] [PubMed] [Google Scholar]
  33. Hedqvist P., Fredholm B. B. Effects of adenosine on adrenergic neurotransmission; prejunctional inhibition and postjunctional enhancement. Naunyn Schmiedebergs Arch Pharmacol. 1976 Jun;293(3):217–223. doi: 10.1007/BF00507344. [DOI] [PubMed] [Google Scholar]
  34. Hedqvist P. Further evidence that prostaglandins inhibit the release of noradrenaline from adrenergic nerve terminals by restriction of availability of calcium. Br J Pharmacol. 1976 Dec;58(4):599–603. doi: 10.1111/j.1476-5381.1976.tb08629.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Hedqvist P., Moawad A. Presynaptic alpha- and beta-adrenoceptor medicated control of noradrenaline release in human oviduct. Acta Physiol Scand. 1975 Dec;95(4):494–496. doi: 10.1111/j.1748-1716.1975.tb10079.x. [DOI] [PubMed] [Google Scholar]
  36. Hertting G., Suko J. Influence of angiotensin, vasopressin or changes in flow rate on vasoconstriction, changes in volume and [3H]-noradrenaline release following postganglionic sympathetic nerve stimulation in the isolated cat spleen. Br J Pharmacol Chemother. 1966 Mar;26(3):686–696. doi: 10.1111/j.1476-5381.1966.tb01848.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Hughes I. E., Kneen B. The effect of propranolol on sympathetic nerve stimulation in isolated vasa deferentia. J Pharm Pharmacol. 1976 Mar;28(3):200–205. doi: 10.1111/j.2042-7158.1976.tb04131.x. [DOI] [PubMed] [Google Scholar]
  38. Hughes J., Kosterlitz H. W., Leslie F. M. Effect of morphine on adrenergic transmission in the mouse vas deferens. Assessment of agonist and antogonist potencies of narcotic analgesics. Br J Pharmacol. 1975 Mar;53(3):371–381. doi: 10.1111/j.1476-5381.1975.tb07373.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Hughes J., Roth R. H. Evidence that angiotensin enhances transmitter release during sympathetic nerve stimulation. Br J Pharmacol. 1971 Feb;41(2):239–255. doi: 10.1111/j.1476-5381.1971.tb08025.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Iversen L. L., Langer S. Z. Effects of phenoxybenzamine on the uptake and metabolism of noradrenaline in the rat heart and vas deferens. Br J Pharmacol. 1969 Nov;37(3):627–637. doi: 10.1111/j.1476-5381.1969.tb08501.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Iversen L. L., Rogawski M. A., Miller R. J. Comparison of the effects of neuroleptic drugs on pre- and postsynaptic dopaminergic mechanisms in the rat striatum. Mol Pharmacol. 1976 Mar;12(2):251–262. [PubMed] [Google Scholar]
  42. KIRPEKAR S. M., CERVONI P. EFFECT OF COCAINE, PHENOXYBENZAMINE AND PHENTOLAMINE ON THE CATECHOLAMINE OUTPUT FROM SPLEEN AND ADRENAL MEDULLA. J Pharmacol Exp Ther. 1963 Oct;142:59–70. [PubMed] [Google Scholar]
  43. Kirpekar S. M., Furchgott R. F., Wakade A. R., Prat J. C. Inhibition by sympathomimetic amines of the release of norepinephrine evoked by nerve stimulation in the cat spleen. J Pharmacol Exp Ther. 1973 Dec;187(3):529–538. [PubMed] [Google Scholar]
  44. Kobinger W., Pichler L. Centrally induced reduction in sympathetic tone-a postsynaptic alpha-adrenoceptor-stimulating action of imidazolines. Eur J Pharmacol. 1976 Dec;40(2):311–320. doi: 10.1016/0014-2999(76)90068-6. [DOI] [PubMed] [Google Scholar]
  45. Langer S. Z., Adler-Graschinsky E., Giorgi O. Physiological significance of alpha-adrenoceptor-mediated negative feedback mechanism regulating noradrenaline release during nerve stimulation. Nature. 1977 Feb 17;265(5595):648–650. doi: 10.1038/265648a0. [DOI] [PubMed] [Google Scholar]
  46. Langer S. Z., Draskóczy P. R., Trendelenburg U. Time course of the development of supersensitivity to various amines in the nictitating membrane of the pithed cat after denervation or decentralization. J Pharmacol Exp Ther. 1967 Aug;157(2):255–273. [PubMed] [Google Scholar]
  47. Langer S. Z., Dubocovich M. L. Subsensitivity of presynaptic alpha-adrenoceptors after exposure to noradrenaline. Eur J Pharmacol. 1977 Jan 7;41(1):87–88. doi: 10.1016/0014-2999(77)90377-6. [DOI] [PubMed] [Google Scholar]
  48. Langer S. Z., Enero M. A. The potentiation of responses to adrenergic nerve stimulation in the presence of cocaine: its relationship to the metabolic fate of released norepinephrine. J Pharmacol Exp Ther. 1974 Dec;191(3):431–443. [PubMed] [Google Scholar]
  49. Langer S. Z. Presynaptic regulation of catecholamine release. Biochem Pharmacol. 1974 Jul 1;23(13):1793–1800. doi: 10.1016/0006-2952(74)90187-7. [DOI] [PubMed] [Google Scholar]
  50. Langer S. Z. Selective metabolic pathways for noradrena-line in the peripheral and in the central nervous system. Med Biol. 1974 Dec;52(6):372–383. [PubMed] [Google Scholar]
  51. Langer S. Z., Stefano F. J., Enero M. A. Pre- and postsynaptic origin of the norepinephrine metabolites formed during transmitter release elicited by nerve stimulation. J Pharmacol Exp Ther. 1972 Oct;183(1):90–102. [PubMed] [Google Scholar]
  52. Langer S. Z. The metabolism of (3H)noradrenaline released by electrical stimulation from the isolated nictitating membrane of the cat and from the vas deferens of the rat. J Physiol. 1970 Jul;208(3):515–546. doi: 10.1113/jphysiol.1970.sp009135. [DOI] [PMC free article] [PubMed] [Google Scholar]
  53. Langer S. Z., Trendelenburg U. The onset of denervation supersensitivity. J Pharmacol Exp Ther. 1966 Jan;151(1):73–86. [PubMed] [Google Scholar]
  54. Langer S. Z., Vogt M. Noradrenaline release from isolated muscles of the nictitating membrane of the cat. J Physiol. 1971 Apr;214(1):159–171. doi: 10.1113/jphysiol.1971.sp009425. [DOI] [PMC free article] [PubMed] [Google Scholar]
  55. Lewis M. J. Effect of acute and chronic treatment with practolol on cardiovascular responses in the pithed rat. J Pharm Pharmacol. 1974 Oct;26(10):783–788. doi: 10.1111/j.2042-7158.1974.tb09174.x. [DOI] [PubMed] [Google Scholar]
  56. Lindmar R., Löffelholz K., Muscholl E. A muscarinic mechanism inhibiting the release of noradrenaline from peripheral adrenergic nerve fibres by nicotinic agents. Br J Pharmacol Chemother. 1968 Feb;32(2):280–294. doi: 10.1111/j.1476-5381.1968.tb00972.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  57. Ljung B., Ablad B., Dahlöf C., Henning M., Hultberg E. Impaired vasoconstrictor nerve function in spontaneously hypertensive rats after long-term treatment with propranolol and metroprolol. Blood Vessels. 1975;12(5):311–315. doi: 10.1159/000158067. [DOI] [PubMed] [Google Scholar]
  58. Lokhandwala M. F., Buckley J. P. Effect of presynaptic alpha-adrenoceptor blockade on responses to cardiac nerve stimulation in anesthetized dogs. Eur J Pharmacol. 1976 Nov;40(1):183–186. doi: 10.1016/0014-2999(76)90369-1. [DOI] [PubMed] [Google Scholar]
  59. Long J. P., Heintz S., Cannon J. G., Kim J. Inhibition of the sympathetic nervous system by 5,6-dihydroxy-2-dimethylamino tetralin (M-7), apomorphine and dopamine. J Pharmacol Exp Ther. 1975 Feb;192(2):336–342. [PubMed] [Google Scholar]
  60. Luchelli-Fortis M. A., Langer S. Z. Selective inhibition by hydrocortisone of 3H-normetanephrine formation during 3H-transmitter release elicited by nerve stimulation in the isolated nerve-muscle preparation of the cat nictitating membrane. Naunyn Schmiedebergs Arch Pharmacol. 1975;287(3):261–275. doi: 10.1007/BF00501472. [DOI] [PubMed] [Google Scholar]
  61. Löffelholz K., Muscholl E. A muscarinic inhibition of the noradrenaline release evoked by postganglionic sympathetic nerve stimulation. Naunyn Schmiedebergs Arch Pharmakol. 1969;265(1):1–15. doi: 10.1007/BF01417206. [DOI] [PubMed] [Google Scholar]
  62. Löffelholz K. Nicotinic drugs and postganglionic sympathetic transmission. Naunyn Schmiedebergs Arch Pharmakol. 1970;267(1):64–73. doi: 10.1007/BF00997115. [DOI] [PubMed] [Google Scholar]
  63. McCulloch M. W., Rand M. J., Story D. F. Inhibition of 3 H-noradrenaline release from sympathetic nerves of guinea-pig atria by a presynaptic -adrenoceptor mechanism. Br J Pharmacol. 1972 Nov;46(3):523P–524P. [PMC free article] [PubMed] [Google Scholar]
  64. Montel H., Starke K. Effects of narcotic analgesics and their antagonists on the rabbit isolated heart and its adrenergic nerves. Br J Pharmacol. 1973 Dec;49(4):628–641. doi: 10.1111/j.1476-5381.1973.tb08538.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  65. Montel H., Starke K., Weber F. Influence of morphine and naloxone on the release of noradrenaline from rat brain cortex slices. Naunyn Schmiedebergs Arch Pharmacol. 1974;283(4):357–369. doi: 10.1007/BF00501109. [DOI] [PubMed] [Google Scholar]
  66. Paalzow G., Paalzow L. Clonidine antinociceptive activity: effects of drugs influencing central monoaminergic and cholinergic mechanisms in the rat. Naunyn Schmiedebergs Arch Pharmacol. 1976;292(2):119–126. doi: 10.1007/BF00498581. [DOI] [PubMed] [Google Scholar]
  67. Robson R. D., Antonaccio M. J. Effect of clonidine on responses to cardiac nerve stimulation as a function of impulse frequency and stimulus duration in vagotomized dogs. Eur J Pharmacol. 1974 Nov;29(1):182–186. doi: 10.1016/0014-2999(74)90189-7. [DOI] [PubMed] [Google Scholar]
  68. Roth R. H., Morgenroth V. H., 3rd, Salzman P. M. Tyrosine hydroxylase: allosteric activation induced by stimulation of central noradrenergic neurons. Naunyn Schmiedebergs Arch Pharmacol. 1975;289(4):327–343. doi: 10.1007/BF00508408. [DOI] [PubMed] [Google Scholar]
  69. STANDISH S. M., SHAFER W. G. Serial histologic effects of rat submaxillary and sublingual salivary gland duct and blood vessel ligation. J Dent Res. 1957 Dec;36(6):866–879. doi: 10.1177/00220345570360060801. [DOI] [PubMed] [Google Scholar]
  70. Scriabine A., Stavorski J. M. Effect of clonidine on cardiac acceleration in vagotomized dogs. Eur J Pharmacol. 1973 Oct;24(1):101–104. doi: 10.1016/0014-2999(73)90119-2. [DOI] [PubMed] [Google Scholar]
  71. Seeman P., Lee T. Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons. Science. 1975 Jun 20;188(4194):1217–1219. doi: 10.1126/science.1145194. [DOI] [PubMed] [Google Scholar]
  72. Serck-Hanssen G. Effects of theophylline and propranolol on acetylcholine-induced release of adrenal medullary catecholamines. Biochem Pharmacol. 1974 Aug 15;23(16):2225–2234. doi: 10.1016/0006-2952(74)90552-8. [DOI] [PubMed] [Google Scholar]
  73. Starke K. Action of angiotensin on uptake, release and metabolism of 14C-noradrenaline by isolated rabbit hearts. Eur J Pharmacol. 1971 Apr;14(2):112–123. doi: 10.1016/0014-2999(71)90204-4. [DOI] [PubMed] [Google Scholar]
  74. Starke K. Alpha sympathomimetic inhibition of adrenergic and cholinergic transmission in the rabbit heart. Naunyn Schmiedebergs Arch Pharmacol. 1972;274(1):18–45. doi: 10.1007/BF00501004. [DOI] [PubMed] [Google Scholar]
  75. Starke K., Altmann K. P. Inhibition of adrenergic neurotransmission by clonidine: an action on prejunctional -receptors. Neuropharmacology. 1973 Apr;12(4):339–347. doi: 10.1016/0028-3908(73)90093-2. [DOI] [PubMed] [Google Scholar]
  76. Starke K., Borowski E., Endo T. Preferential blockade of presynaptic alpha-adrenoceptors by yohimbine. Eur J Pharmacol. 1975 Dec;34(2):385–388. doi: 10.1016/0014-2999(75)90268-x. [DOI] [PubMed] [Google Scholar]
  77. Starke K., Endo T., Taube H. D. Relative pre- and postsynaptic potencies of alpha-adrenoceptor agonists in the rabbit pulmonary artery. Naunyn Schmiedebergs Arch Pharmacol. 1975;291(1):55–78. doi: 10.1007/BF00510821. [DOI] [PubMed] [Google Scholar]
  78. Starke K. Influence of extracellular noradrenaline on the stimulation-evoked secretion of noradrenaline from sympathetic nerves: evidence for an -receptor-mediated feed-back inhibition of noradrenaline release. Naunyn Schmiedebergs Arch Pharmacol. 1972;275(1):11–23. doi: 10.1007/BF00505064. [DOI] [PubMed] [Google Scholar]
  79. Starke K. Interactions of angiotensin and cocaine on the output of noradrenaline from isolated rabbit hearts. Naunyn Schmiedebergs Arch Pharmakol. 1970;265(4):383–386. doi: 10.1007/BF00997196. [DOI] [PubMed] [Google Scholar]
  80. Starke K., Montel H. Alpha-receptor-mediated modulation of transmitter release from central noradrenergic neurones. Naunyn Schmiedebergs Arch Pharmacol. 1973;279(1):53–60. doi: 10.1007/BF00502067. [DOI] [PubMed] [Google Scholar]
  81. Starke K., Montel H., Gayk W., Merker R. Comparison of the effects of clonidine on pre- and postsynaptic adrenoceptors in the rabbit pulmonary artery. Alpha-sympathomimetic inhibition of Neurogenic vasoconstriction. Naunyn Schmiedebergs Arch Pharmacol. 1974;285(2):133–150. doi: 10.1007/BF00501149. [DOI] [PubMed] [Google Scholar]
  82. Starke K., Montel H., Schümann H. J. Influence of cocaine and phenoxybenzamine on noradrenaline uptake and release. Naunyn Schmiedebergs Arch Pharmakol. 1971;270(2):210–214. doi: 10.1007/BF00997091. [DOI] [PubMed] [Google Scholar]
  83. Steinsland O. S., Furchgott R. F., Kirpekar S. M. Inhibition of adrenergic neurotransmission by parasympathomimetics in the rabbit ear artery. J Pharmacol Exp Ther. 1973 Feb;184(2):346–356. [PubMed] [Google Scholar]
  84. Stj-5aarne L., Brundin J. Dual adreoceptor-mediated control of noradrenaline secretion from human vasoconstrictor nerves: facilitation by BETA-receptors and inhibitor by alpha-receptors. Acta Physiol Scand. 1975 May;94(1):139–141. doi: 10.1111/j.1748-1716.1975.tb05872.x. [DOI] [PubMed] [Google Scholar]
  85. Stjärne L., Brundin J. Additive stimulating effects of inhibitor of prostaglandin synthesis and of beta-adrenoceptor agonist on sympathetic neuroeffector function in human omental blood vessels. Acta Physiol Scand. 1976 Jun;97(2):267–269. doi: 10.1111/j.1748-1716.1976.tb10262.x. [DOI] [PubMed] [Google Scholar]
  86. Stjärne L., Brundin J. Beta2-adrenoceptors facilitating noradrenaline secretion from human vasoconstrictor nerves. Acta Physiol Scand. 1976 Mar;97(1):88–93. doi: 10.1111/j.1748-1716.1976.tb10238.x. [DOI] [PubMed] [Google Scholar]
  87. Stjärne L., Gripe K. Prostaglandin-dependent and -independent feedback control of noradrenaline secretion in vasoconstrictor nerves of normotensive human subjects. A preliminary report. Naunyn Schmiedebergs Arch Pharmacol. 1973;280(4):441–446. doi: 10.1007/BF00506634. [DOI] [PubMed] [Google Scholar]
  88. Stjärne L. Inhibitory effect of prostaglandin E2 on noradrenaline secretion from sympathetic nerves as a function of external calcium. Prostaglandins. 1973 Jan;3(1):105–109. doi: 10.1016/0090-6980(73)90142-1. [DOI] [PubMed] [Google Scholar]
  89. Szerb J. C., Somogyi G. T. Depression of acetylcholine release from cerebral cortical slices by cholinesterase inhibition and by oxotremorine. Nat New Biol. 1973 Jan 24;241(108):121–122. doi: 10.1038/newbio241121a0. [DOI] [PubMed] [Google Scholar]
  90. V Euler U. S., Gaddum J. H. An unidentified depressor substance in certain tissue extracts. J Physiol. 1931 Jun 6;72(1):74–87. doi: 10.1113/jphysiol.1931.sp002763. [DOI] [PMC free article] [PubMed] [Google Scholar]
  91. Vogel S. A., Silberstein S. D., Berv K. R., Kopin I. J. Stimulation-induced release of norepinephrine from rat superior cervical ganglia in vitro. Eur J Pharmacol. 1972 Dec;20(3):308–311. doi: 10.1016/0014-2999(72)90191-4. [DOI] [PubMed] [Google Scholar]
  92. Westfall T. C., Kitay D., Wahl G. The effect of cyclic nucleotides on the release of 3H-dopamine from rat striatal slices. J Pharmacol Exp Ther. 1976 Oct;199(1):149–157. [PubMed] [Google Scholar]
  93. Wooten G. F., Thoa N. B., Kopin I. J., Axelrod J. Enhanced release of dopamine -hydroxylase and norepinephrine from sympathetic nerves by dibutyryl cyclic adenosine 3', 5'-monophosphate and theophylline. Mol Pharmacol. 1973 Mar;9(2):178–183. [PubMed] [Google Scholar]

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