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. 1975 Jan 4;1(5948):12–14. doi: 10.1136/bmj.1.5948.12-a

I alpha-hydroxycholecalciferol: a treatment of renal bone disease.

G R Catto, M MacLeod, B Pelc, E Kodicek
PMCID: PMC1671878  PMID: 1120218

Abstract

Three patients with chronic renal failure on maintenance haemodialysis have been treated with 1 alpha-hydroxycholecalciferol (1 alpha-OHCC), a synthetic vitamin D analogue. A daily dose of 2 mug by mouth produced a significant increase in both calcium absorption from the gastrointestinal tract and calcium content of bone. Treatment with 1 alpha-OHCC appears to be effective in cases of metabolic bone disease associated with chronic renal failure.

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Selected References

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