Skip to main content
PMC home page
British Medical Journal logoLink to British Medical Journal
. 1975 May 3;2(5965):241–245. doi: 10.1136/bmj.2.5965.241

Myocardial infarction in young women with special reference to oral contraceptive practice.

J I Mann, M P Vessey, M Thorogood, S R Doll
PMCID: PMC1673246  PMID: 1169093

Abstract

Sixty-three women discharged from hospital with a diagnosis of myocardial infarction and 189 control patients were studied. All were under 45 years of age at the time of admission. Current oral contraceptive use, heavy cigarette smoking, treated hypertension and diabetes, pre-eclamptic toxaemia, and obesity were all reported by, and type II hyperlipoproteinaemia was found more often in, patients with myocardial infarction than their controls. The relationship between myocardial infarction and oral contraceptives could not be explained in terms of an association between the use of these preparations and the other factors. The combined effect of the risk factors was clearly synergistic.

Full text

PDF
241

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beaumont J. L., Carlson L. A., Cooper G. R., Fejfar Z., Fredrickson D. S., Strasser T. Classification of hyperlipidaemias and hyperlipoproteinaemias. Bull World Health Organ. 1970;43(6):891–915. [PMC free article] [PubMed] [Google Scholar]
  2. Carlson L. A., Böttiger L. E. Ischaemic heart-disease in relation to fasting values of plasma triglycerides and cholesterol. Stockholm prospective study. Lancet. 1972 Apr 22;1(7756):865–868. doi: 10.1016/s0140-6736(72)90738-6. [DOI] [PubMed] [Google Scholar]
  3. Goldbourt U., Medalie J. H. Weight-height indices. Choice of the most suitable index and its association with selected variables among 10,000 adult males of heterogeneous origin. Br J Prev Soc Med. 1974 May;28(2):116–126. doi: 10.1136/jech.28.2.116. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Inman W. H., Vessey M. P. Investigation of deaths from pulmonary, coronary, and cerebral thrombosis and embolism in women of child-bearing age. Br Med J. 1968 Apr 27;2(5599):193–199. doi: 10.1136/bmj.2.5599.193. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Inman W. H., Vessey M. P., Westerholm B., Engelund A. Thromboembolic disease and the steroidal content of oral contraceptives. A report to the Committee on Safety of Drugs. Br Med J. 1970 Apr 25;2(5703):203–209. doi: 10.1136/bmj.2.5703.203. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Kannel W. B., Castelli W. P., Gordon T., McNamara P. M. Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study. Ann Intern Med. 1971 Jan;74(1):1–12. doi: 10.7326/0003-4819-74-1-1. [DOI] [PubMed] [Google Scholar]
  7. Kay C. R., Smith A., Richards B. Smoking habits of oral contraceptive users. Lancet. 1969 Dec 6;2(7632):1228–1229. doi: 10.1016/s0140-6736(69)90756-9. [DOI] [PubMed] [Google Scholar]
  8. Mann J. I., Inman W. H. Oral contraceptives and death from myocardial infarction. Br Med J. 1975 May 3;2(5965):245–248. doi: 10.1136/bmj.2.5965.245. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Mulcahy R., Hickey N., Maurer B. Coronary heart disease in women. Study of risk factors in 100 patients less than 60 years of age. Circulation. 1967 Oct;36(4):577–586. doi: 10.1161/01.cir.36.4.577. [DOI] [PubMed] [Google Scholar]
  10. Oliver M. F. Ischaemic heart disease in young women. Br Med J. 1974 Nov 2;4(5939):253–259. doi: 10.1136/bmj.4.5939.253. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Pike M. C., Morrow R. H. Statistical analysis of patient-control studies in epidemiology. Factor under investigation an all-or-none variable. Br J Prev Soc Med. 1970 Feb;24(1):42–44. doi: 10.1136/jech.24.1.42. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Stokes T., Wynn V. Serum-lipids in women on oral contraceptives. Lancet. 1971 Sep 25;2(7726):677–680. doi: 10.1016/s0140-6736(71)92247-1. [DOI] [PubMed] [Google Scholar]
  13. Vessey M. P., Doll R., Peto R., Redman G. Characteristics of women using different methods of contraception--some preliminary findings from a prospective study. Int J Epidemiol. 1972 Summer;1(2):119–123. doi: 10.1093/ije/1.2.119. [DOI] [PubMed] [Google Scholar]
  14. Vessey M. P. Thromboembolism, cancer, and oral contraceptives. Clin Obstet Gynecol. 1974 Mar;17(1):65–78. doi: 10.1097/00003081-197403000-00009. [DOI] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES