Abstract
Forty-six patients with histologically verified chronic active hepatitis (CAH) were divided into three groups according to whether the CAH was virus-induced, drug-induced, or cryptogenic. The frequency of the HL-A antigens 1 and 8 was increased in the cryptogenic group while the other groups did not differ significantly from healthy controls. Autoantibodies were often found in high titres in the drug-induced and cryptogenic groups but were infrequent in the virus-induced group.
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- Alarcón-Segovia D., Wakim K. G., Worthington J. W., Ward L. E. Clinical and experimental studies on the hydralazine syndrome and its relationship to systemic lupus erythematosus. Medicine (Baltimore) 1967 Jan;46(1):1–33. doi: 10.1097/00005792-196701000-00001. [DOI] [PubMed] [Google Scholar]
- Bhagwat A. G., Warren R. E. Hepatic reaction to nitrofurantoin. Lancet. 1969 Dec 20;2(7634):1369–1369. doi: 10.1016/s0140-6736(69)90921-0. [DOI] [PubMed] [Google Scholar]
- De Groote J., Desmet V. J., Gedigk P., Korb G., Popper H., Poulsen H., Scheuer P. J., Schmid M., Thaler H., Uehlinger E. A classification of chronic hepatitis. Lancet. 1968 Sep 14;2(7568):626–628. doi: 10.1016/s0140-6736(68)90710-1. [DOI] [PubMed] [Google Scholar]
- ECKER J. A. PHENYLBUTAZONE HEPATITIS. Am J Gastroenterol. 1965 Jan;43:23–29. [PubMed] [Google Scholar]
- Eddleston A. L., Williams R. Inadequate antibody response to hBAg or suppressor T-cell defect in development of active chronic hepatitis. Lancet. 1974 Dec 28;2(7896):1543–1545. doi: 10.1016/s0140-6736(74)90287-6. [DOI] [PubMed] [Google Scholar]
- Iwarson S., Lundin P., Holmgren J., Hermodsson S. Multiple attacks of hepatitis in drug addicts: biochemical, immunochemical, and morphologic characteristics. J Infect Dis. 1973 May;127(5):544–550. doi: 10.1093/infdis/127.5.544. [DOI] [PubMed] [Google Scholar]
- Mackay I. R., Morris P. J. Association of autoimmune active chronic hepatitis with HL-A1,8. Lancet. 1972 Oct 14;2(7781):793–795. doi: 10.1016/s0140-6736(72)92149-6. [DOI] [PubMed] [Google Scholar]
- Maddrey W. C., Boitnott J. K. Isoniazid hepatitis. Ann Intern Med. 1973 Jul;79(1):1–12. doi: 10.7326/0003-4819-79-1-1. [DOI] [PubMed] [Google Scholar]
- McQuillin J., Gardner P. S., McGuckin R. Rapid diagnosis of influenza by immunofluorescent techniques. Lancet. 1970 Oct 3;2(7675):690–695. doi: 10.1016/s0140-6736(70)91961-6. [DOI] [PubMed] [Google Scholar]
- Morphological criteria in viral hepatitis. Review by an international group. Lancet. 1971 Feb 13;1(7694):333–337. [PubMed] [Google Scholar]
- Reynolds T. B., Peters R. L., Yamada S. Chronic active and lupoid hepatitis caused by a laxative, oxyphenisatin. N Engl J Med. 1971 Oct 7;285(15):813–820. doi: 10.1056/NEJM197110072851501. [DOI] [PubMed] [Google Scholar]
- Schweitzer I. L., Peters R. L. Acute submassive hepatic necrosis due to methyldopa. A case demonstrating possible initiation of chronic liver disease. Gastroenterology. 1974 Jun;66(6):1203–1211. [PubMed] [Google Scholar]
- Wright R. Australia antigen and smooth-muscle antibody in acute and chronic hepatitis. Lancet. 1970 Mar 7;1(7645):521–522. doi: 10.1016/S0140-6736(70)91605-3. [DOI] [PMC free article] [PubMed] [Google Scholar]