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. 2000 Nov 22;267(1459):2281–2286. doi: 10.1098/rspb.2000.1280

Robustness as an evolutionary principle.

S Bornholdt 1, K Sneppen 1
PMCID: PMC1690809  PMID: 11413644

Abstract

We suggest simulating evolution of complex organisms using a model constrained solely by the requirement of robustness in its expression patterns. This scenario is illustrated by evolving discrete logical networks with epigenetic properties. Evidence for dynamical features in the evolved networks is found that can be related to biological observables.

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Selected References

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