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. 1993 Oct;83(10):1385–1389. doi: 10.2105/ajph.83.10.1385

Clinical research, prophylaxis, therapy, and care for HIV disease in Africa.

K M De Cock 1, S B Lucas 1, S Lucas 1, J Agness 1, A Kadio 1, H D Gayle 1
PMCID: PMC1694848  PMID: 8214225

Abstract

By the end of the century, citizens of resource-poor countries will constitute 90% of the world's human immunodeficiency virus (HIV)-infected people. Clinical management of such persons in developing countries has been neglected; most AIDS research has concentrated on epidemiology, and donor agencies have generally invested in the prevention of HIV infection. The heavy burden of HIV disease in Africa requires that care for AIDS be addressed, and prevention and care should be seen as interrelated. Prevention and treatment of tuberculosis, the commonest severe infection in persons with AIDS in Africa, illustrate this interrelationship. We outline priorities for applied research on the management of HIV disease in a resource-poor environment, and discuss prophylaxis, therapy for opportunistic diseases, terminal care, and use of antiretroviral therapy. Research should define the standard of care that can realistically be demanded for HIV disease in a resource-poor environment. Research and public health programs for AIDS in developing countries must address AIDS care and attempt to reduce the widening gap between interventions available for HIV-infected persons in different parts of the world.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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