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. 1970 Nov;11(11):215–226.

Chronic and acute toxicity of the chlorinated hydrocarbon insecticides in mammals and birds.

V V St Omer
PMCID: PMC1695123  PMID: 4992437

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anders F. Tumour formation in platyfish-swordtail hybrids as a problem of gene regulation. Experientia. 1967 Jan 15;23(1):1–10. doi: 10.1007/BF02142235. [DOI] [PubMed] [Google Scholar]
  2. BAECKSTROEM J., HANSSON E., ULLBERG S. DISTRIBUTION OF C14-DDT AND C14-DIELDRIN IN PREGNANT MICE DETERMINED BY WHOLE-BODY AUTORADIOGRAPHY. Toxicol Appl Pharmacol. 1965 Jan;7:90–96. doi: 10.1016/0041-008x(65)90079-7. [DOI] [PubMed] [Google Scholar]
  3. BALL W. L., KAY K., SINCLAIR J. W. Observations on toxicity of aldrin. I. Growth and estrus in rats. AMA Arch Ind Hyg Occup Med. 1953 Apr;7(4):292–300. [PubMed] [Google Scholar]
  4. BALL W. L., SINCLAIR J. W., CREVIER M., KAY K. Modification of parathion's toxicity for rats by pretreatment with chlorinated hydrocarbon insecticides. Can J Biochem Physiol. 1954 Jul;32(4):440–445. [PubMed] [Google Scholar]
  5. BLEIBERG M. J., CEFARATI M., KLINMANN, KORNBLITH P. Studies of choline acetylase inhibition by DDA (dichloro-diphenylacetic acid) and its possible relationship to DDT toxicity. Toxicol Appl Pharmacol. 1962 May;4:292–312. doi: 10.1016/0041-008x(62)90042-x. [DOI] [PubMed] [Google Scholar]
  6. BRADLOW H. L., FUKUSHIMA D. K., ZUMOFF B., HELLMAN L., GALLAGHER T. F. A PERIPHERAL ACTION OF O,P' -DDD ON STEROID BIOTRANSFORMATION. J Clin Endocrinol Metab. 1963 Sep;23:918–922. doi: 10.1210/jcem-23-9-918. [DOI] [PubMed] [Google Scholar]
  7. BURLINGTON H., LINDEMAN V. F. Effect of DDT on testes and secondary sex characters of white leghorn cockerels. Proc Soc Exp Biol Med. 1950 May;74(1):48–51. doi: 10.3181/00379727-74-17805. [DOI] [PubMed] [Google Scholar]
  8. CAZORLA A., MONCLOA F. Action of 1,1,dichloro-2-p-chlorophenyl-2-o-chlorophenylethane on dog adrenal cortex. Science. 1962 Apr 6;136(3510):47–47. doi: 10.1126/science.136.3510.47. [DOI] [PubMed] [Google Scholar]
  9. CUETO C., BROWN J. H., RICHARDSON A. P., Jr Biological studies on an adrenocorticolytic agent and the isolation of the active components. Endocrinology. 1958 Mar;62(3):334–339. doi: 10.1210/endo-62-3-334. [DOI] [PubMed] [Google Scholar]
  10. CUETO C., Jr, DURHAM W. F., HAYES W. J., Jr The effect of known repeated oral doses of chlorophenothane (DDT) in man. J Am Med Assoc. 1956 Oct 27;162(9):890–897. doi: 10.1001/jama.1956.72970260008012. [DOI] [PubMed] [Google Scholar]
  11. DALE W. E., GAINES T. B., HAYES W. J., PEARCE G. W. POISONING BY DDT: RELATION BETWEEN CLINICAL SIGNS AND CONCENTRATION IN RAT BRAIN. Science. 1963 Dec 13;142(3598):1474–1476. doi: 10.1126/science.142.3598.1474. [DOI] [PubMed] [Google Scholar]
  12. DAVIDOW B., FRAWLEY J. P. Tissue distribution, accumulation and elimination of the isomers of benzene hexachloride. Proc Soc Exp Biol Med. 1951 Apr;76(4):780–783. doi: 10.3181/00379727-76-18631. [DOI] [PubMed] [Google Scholar]
  13. DAVIS K. J., FITZHUGH O. G. Tumorigenic potential of aldrin and dieldrin for mice. Toxicol Appl Pharmacol. 1962 Mar;4:187–189. doi: 10.1016/0041-008x(62)90056-x. [DOI] [PubMed] [Google Scholar]
  14. DINAMARCA M. L., AGOSIN M., NEGHME A. The metabolic fate of C-14-DDT in Triatoma infestans. Exp Parasitol. 1962 Feb;12:61–72. doi: 10.1016/0014-4894(62)90070-x. [DOI] [PubMed] [Google Scholar]
  15. Ecobichon D. J., Saschenbrecker P. W. Pharmacodynamic study of DDT in cockerels. Can J Physiol Pharmacol. 1968 Sep;46(5):785–794. doi: 10.1139/y68-121. [DOI] [PubMed] [Google Scholar]
  16. Ecobichon D. J., Saschenbrecker P. W. The redistribution of stored DDT in cockerels under the influence of food deprivation. Toxicol Appl Pharmacol. 1969 Sep;15(2):420–432. doi: 10.1016/0041-008x(69)90040-4. [DOI] [PubMed] [Google Scholar]
  17. FINNEGAN J. K., HAAG H. B., LARSON P. S. Tissue distribution and elimination of DDD and DDT following oral administration to dogs and rats. Proc Soc Exp Biol Med. 1949 Nov;72(2):357–360. doi: 10.3181/00379727-72-17431. [DOI] [PubMed] [Google Scholar]
  18. FITZHUGH O. G., NELSON A. A., FRAWLEY J. P. The chronic toxicities of technical benzene hexachloride and its alpha, beta and gamma isomers. J Pharmacol Exp Ther. 1950 Sep;100(1):59–66. [PubMed] [Google Scholar]
  19. FITZHUGH O. G., NELSON A. A., QUAIFE M. L. CHRONIC ORAL TOXICITY OF ALDRIN AND DIELDRIN IN RATS AND DOGS. Food Cosmet Toxicol. 1964 Nov;2:551–562. doi: 10.1016/s0015-6264(64)80354-0. [DOI] [PubMed] [Google Scholar]
  20. FREUNDT K. J., KIESE M. [Absorption by the lungs of dieldrin released in the air by steam]. Arch Toxikol. 1962;19:313–320. [PubMed] [Google Scholar]
  21. GAINES T. B. The acute toxicity of pesticides to rats. Toxicol Appl Pharmacol. 1960 Jan;2:88–99. doi: 10.1016/0041-008x(60)90074-0. [DOI] [PubMed] [Google Scholar]
  22. GOWDEY C. W., GRAHAM A. R., SEGUIN J. J., STAVRAKY G. W. The pharmacological properties of the insecticide dieldrin. Can J Biochem Physiol. 1954 Sep;32(5):498–503. [PubMed] [Google Scholar]
  23. GOWDEY C. W., GRAHAM A. R., SEGUIN J. J., STAVRAKY G. W., WAUD R. A. A study of the pharmacological properties of the insecticide aldrin (hexachlorohexahydrodimethanonaphthalene). Can J Med Sci. 1952 Dec;30(6):520–533. doi: 10.1139/cjms52-066. [DOI] [PubMed] [Google Scholar]
  24. GRADY H. J., AZARNOFF D. L., CREAGAR R., HUFFMAN D. H., NICHOLS J. SPECIFICITY OF ENZYME INHIBITION BY DDD. Proc Soc Exp Biol Med. 1965 May;119:238–241. doi: 10.3181/00379727-119-30146. [DOI] [PubMed] [Google Scholar]
  25. HART L. G., SHULTICE R. W., FOUTS J. R. Stimulatory effects of chlordane on hepatic microsomal drug metabolism in the rat. Toxicol Appl Pharmacol. 1963 May;5:371–386. doi: 10.1016/0041-008x(63)90096-6. [DOI] [PubMed] [Google Scholar]
  26. HATHWAY D. E., MALLINSON A., AKINTONWA D. A. EFFECTS OF DIELDRIN, PICROTOXIN AND TELODRIN ON THE METABOLISM OF AMMONIA IN BRAIN. Biochem J. 1965 Mar;94:676–686. doi: 10.1042/bj0940676. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. HAYES W. J., Jr REVIEW OF THE METABOLISM OF CHLORINATED HYDROCARBON INSECTICIDES EXPECIALLY IN MAMMALS. Annu Rev Pharmacol. 1965;5:27–52. doi: 10.1146/annurev.pa.05.040165.000331. [DOI] [PubMed] [Google Scholar]
  28. HUKUHARA T. [Distribution of DDT between the brain and fatty tissue in experimental feeding in rats and behavior of fat-stored DDT in the starvation state]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1962;242:522–539. [PubMed] [Google Scholar]
  29. Harvey J. M. Excretion of DDT by migratory birds. Can J Zool. 1967 Sep;45(5):629–633. doi: 10.1139/z67-079. [DOI] [PubMed] [Google Scholar]
  30. Hathway D. E., Mallinson A. Chemical studies in relation to convulsive conditions. Effect of Telodrin on the liberation and utilization of ammonia in rat brain. Biochem J. 1964 Jan;90(1):51–60. doi: 10.1042/bj0900051. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Hodge H. C., Boyce A. M., Deichmann W. B., Kraybill H. F. Toxicology and no-effect levels of aldrin and dieldrin. Toxicol Appl Pharmacol. 1967 Mar;10(3):613–675. doi: 10.1016/0041-008x(67)90100-7. [DOI] [PubMed] [Google Scholar]
  32. KAY K. STATE OF KNOWLEDGE ON HUMAN EXPOSURES AND BIOLOGIC EFFECTS OF ECONOMIC POISONS. Clin Pharmacol Ther. 1964 Nov-Dec;5:737–752. doi: 10.1002/cpt196456part1737. [DOI] [PubMed] [Google Scholar]
  33. KIMBROUGH R., GAINES T. B., SHERMAN J. D. NUTRITIONAL FACTORS, LONG-TERM DDT INTAKE, AND CHLOROLEUKEMIA IN RATS. J Natl Cancer Inst. 1964 Aug;33:215–225. [PubMed] [Google Scholar]
  34. Koeman J. H., Oudejans R. C., Huisman E. A. Danger of chlorinated hydrocarbon insecticides in birds' eggs. Nature. 1967 Sep 2;215(5105):1094–1096. doi: 10.1038/2151094a0. [DOI] [PubMed] [Google Scholar]
  35. Konst H., Plummer P. J. Studies on the Toxity of DDT. Can J Comp Med Vet Sci. 1946 May;10(5):128–136. [PMC free article] [PubMed] [Google Scholar]
  36. LIPKE H., KEARNS C. W. DDT dehydrochlorinase. I. Isolation, chemical properties, and spectrophotometric assay. J Biol Chem. 1959 Aug;234(8):2123–2128. [PubMed] [Google Scholar]
  37. Morin E. W., Robertson A., Beauregard M. Endrin poisoning in chickens. Can Vet J. 1970 Apr;11(4):74–77. [PMC free article] [PubMed] [Google Scholar]
  38. NICHOLS J., GARDNER L. I. Production of insulin sensitivity with the adrenocorticolytic drug DDD (2,2-bis (parachlorophenyl)-1,1-dichloroethane). J Lab Clin Med. 1951 Feb;37(2):229–238. [PubMed] [Google Scholar]
  39. NICHOLS J., RICHARDSON A. W. Effects of DDD on steroid response and blood flow through the adrenal after ACTH. Proc Soc Exp Biol Med. 1960 Aug-Sep;104:539–542. doi: 10.3181/00379727-104-25901. [DOI] [PubMed] [Google Scholar]
  40. O'BRIEN R. D., MATSUMURA F. DDT: A NEW HYPOTHESIS OF ITS MODE OF ACTION. Science. 1964 Oct 30;146(3644):657–658. doi: 10.1126/science.146.3644.657. [DOI] [PubMed] [Google Scholar]
  41. OZBURN G. W., MORRISON F. O. Development of a DDT-tolerant strain of laboratory mice. Nature. 1962 Dec 8;196:1009–1010. doi: 10.1038/1961009b0. [DOI] [PubMed] [Google Scholar]
  42. PERRY A. S., HOSKINS W. M. The detoxification of DDT by resistant houseflies and inhibition of this process by piperonyl cyclonene. Science. 1950 Jun 2;111(2892):600–601. doi: 10.1126/science.111.2892.600. [DOI] [PubMed] [Google Scholar]
  43. PETERSON J. E., ROBISON W. H. METABOLIC PRODUCTS OF P,P'-DDT IN THE RAT. Toxicol Appl Pharmacol. 1964 May;6:321–327. doi: 10.1016/0041-008x(64)90073-0. [DOI] [PubMed] [Google Scholar]
  44. PINTO J. D., CAMIEN M. N., DUNN M. S. METABOLIC FATE OF P,P'-DDT (1,1,1-TRICHLORO-2,2-BIS(P-CHLOROPHENYL)ETHANE)IN RATS. J Biol Chem. 1965 May;240:2148–2154. [PubMed] [Google Scholar]
  45. RADOMSKI J. L., DAVIDOW B. The metabolite of heptachlor, its estimation storage, and toxicity. J Pharmacol Exp Ther. 1953 Mar;107(3):266–272. [PubMed] [Google Scholar]
  46. ROSENBERG M. M., TANAKA T., ADLER H. E. Toxicity of chlordan to laying pullets. Am J Vet Res. 1950 Apr;11(39):236–239. [PubMed] [Google Scholar]
  47. ROSENBERG M. M., TANAKA T. Toxicity of chlordan to growing chickens. Am J Vet Res. 1950 Apr;11(39):233–235. [PubMed] [Google Scholar]
  48. STOHLMAN E. F., THORP W. T. S., SMITH M. I. Toxic action of chlordan. Arch Ind Hyg Occup Med. 1950 Jan;1(1):13–19. [PubMed] [Google Scholar]
  49. STREET J. C. DDT ANTAGONISM TO DIELDRIN STORAGE IN ADIPOSE TISSUE OF RATS. Science. 1964 Dec 18;146(3651):1580–1581. doi: 10.1126/science.146.3651.1580. [DOI] [PubMed] [Google Scholar]
  50. TAUBER O. E., HUGHES A. B. Effect of DDT ingestion on total cholesterol content of ovaries of white rat. Proc Soc Exp Biol Med. 1950 Nov;75(2):420–422. doi: 10.3181/00379727-75-18217. [DOI] [PubMed] [Google Scholar]
  51. TSUKADA Y., TAKAGAKI G., SUGIMOTO S., HIRANO S. Changes in the ammonia and glutamine content of the rat brain induced by electric shock. J Neurochem. 1958;2(4):295–303. doi: 10.1111/j.1471-4159.1958.tb12378.x. [DOI] [PubMed] [Google Scholar]
  52. Telford H. S., Guthrie J. E. TRANSMISSION OF THE TOXICITY OF DDT THROUGH THE MILK OF WHITE RATS AND GOATS. Science. 1945 Dec 21;102(2660):647–647. doi: 10.1126/science.102.2660.647. [DOI] [PubMed] [Google Scholar]
  53. Tinsley I. J. DDT ingestion and liver glucose 6-phosphate dehydrogenase activity. II. Biochem Pharmacol. 1965 May;14(5):847–851. doi: 10.1016/0006-2952(65)90104-8. [DOI] [PubMed] [Google Scholar]
  54. VRBA R. A source of ammonia and changes of protein structure in the rat brain during physical exertion. Nature. 1955 Jul 16;176(4472):117–118. doi: 10.1038/176117a0. [DOI] [PubMed] [Google Scholar]
  55. VRBA R. Significance of glutamic acid in metabolic processes in the rat brain during physical exercise. Nature. 1955 Dec 31;176(4496):1258–1261. doi: 10.1038/1761258a0. [DOI] [PubMed] [Google Scholar]
  56. WINTERINGHAM F. P., BARNES J. M. Comparative response of insects and mammals to certain halogenated hydrocarbons used as insecticides. Physiol Rev. 1955 Jul;35(3):701–739. doi: 10.1152/physrev.1955.35.3.701. [DOI] [PubMed] [Google Scholar]
  57. Woodard G., Ofner R. R., Montgomery C. M. ACCUMULATION OF DDT IN THE BODY FAT AND ITS APPEARANCE IN THE MILK OF DOGS. Science. 1945 Aug 17;102(2642):177–178. doi: 10.1126/science.102.2642.177-a. [DOI] [PubMed] [Google Scholar]

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