Abstract
The plasma magnesium concentration has been determined in 73 patients with primary hyperparathyroidism. In most patients it lay within the normal range (1·7-2·3 mg./100 ml.), but in five it was less than 1·6 mg./100 ml. These patients had relatively high urinary magnesium outputs, and one of them, studied in greater detail, failed to retain parenterally administered magnesium. Hence hypomagnesaemia in hyperparathyroidism may be associated with a defect in renal magnesium conservation, which may be reversible.
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- BARNES B. A., KRANE S. M., COPE O. Magnesium studies in relation to hyperparathyroidism. J Clin Endocrinol Metab. 1957 Dec;17(12):1407–1421. doi: 10.1210/jcem-17-12-1407. [DOI] [PubMed] [Google Scholar]
- Briscoe A. M., Ragan C. Relation of magnesium to calcium in human blood serum. Nature. 1967 Jun 10;214(5093):1126–1127. doi: 10.1038/2141126b0. [DOI] [PubMed] [Google Scholar]
- Bulger H. A., Gausmann F. MAGNESIUM METABOLISM IN HYPERPARATHYROIDISM. J Clin Invest. 1933 Nov;12(6):1135–1142. doi: 10.1172/JCI100564. [DOI] [PMC free article] [PubMed] [Google Scholar]
- CLARKSON E. M., MCDONALD S. J., DEWARDENER H. E., WARREN R. MAGNESIUM METABOLISM IN CHRONIC RENAL FAILURE. Clin Sci. 1965 Feb;28:107–115. [PubMed] [Google Scholar]
- DENT C. E., HARPER C. M., PHILPOT G. R. The treatment of renal-glomerular osteodystrophy. Q J Med. 1961 Jan;30:1–31. [PubMed] [Google Scholar]
- DENT C. E. Some problems of hyperparathyroidism. Br Med J. 1962 Dec 1;2(5317):1419–1425. doi: 10.1136/bmj.2.5317.1419. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Davies D. R., Dent C. E., Watson L. Tertiary hyperparathyroidism. Br Med J. 1968 Aug 17;3(5615):395–399. doi: 10.1136/bmj.3.5615.395. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dent C. E., Watson L. The hydrocortisone test in primary and tertiary hyperparathyroidism. Lancet. 1968 Sep 21;2(7569):662–664. doi: 10.1016/s0140-6736(68)92509-9. [DOI] [PubMed] [Google Scholar]
- Dunn M. J., Walser M. Magnesium depletion in normal man. Metabolism. 1966 Oct;15(10):884–895. doi: 10.1016/0026-0495(66)90159-4. [DOI] [PubMed] [Google Scholar]
- FITZGERALD M. G., FOURMAN P. An experimental study of magnesium deficiency in man. Clin Sci. 1956 Nov;15(4):635–647. [PubMed] [Google Scholar]
- HANNA S., NORTH K. A., MACINTYRE I., FRASER R. Magnesium metabolism in parathyroid disease. Br Med J. 1961 Nov 11;2(5262):1253–1256. doi: 10.1136/bmj.2.5262.1253. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HARMON M. Parathyroid adenoma in a child; report of a case presenting as central nervous system disease and complicated by magnesium deficiency. AMA J Dis Child. 1956 Apr;91(4):313–325. doi: 10.1001/archpedi.1956.02060020315001. [DOI] [PubMed] [Google Scholar]
- Jones K. H., Fourman P. Effects of infusions of magnesium and of calcium in parathyroid insufficiency. Clin Sci. 1966 Feb;30(1):139–150. [PubMed] [Google Scholar]
- MacDonald M. A., Watson L. The determination of magnesium in biological materials by atomic absorption spectrophotometry. Clin Chim Acta. 1966 Aug;14(2):233–241. doi: 10.1016/0009-8981(66)90093-3. [DOI] [PubMed] [Google Scholar]
- Pyrah L. N., Hodgkinson A., Anderson C. K. Primary hyperparathyroidism. Br J Surg. 1966 Apr;53(4):245–316. doi: 10.1002/bjs.1800530402. [DOI] [PubMed] [Google Scholar]
- Sanderson P. H. Renal potassium wasting in hypercalcaemia. Br Med J. 1967 Mar 18;1(5541):679–680. doi: 10.1136/bmj.1.5541.679. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Steele T. H., Wen S. F., Evenson M. A., Rieselbach R. E. The contribution of the chronically diseased kidney to magnesium homeostasis in man. J Lab Clin Med. 1968 Mar;71(3):455–463. [PubMed] [Google Scholar]
- Sutton R. A., Watson L. Urinary excretion of calcium and magnesium in primary hyperparathyroidism. Lancet. 1969 May 17;1(7603):1000–1003. doi: 10.1016/s0140-6736(69)91800-5. [DOI] [PubMed] [Google Scholar]
- Zimmet P., Breidahl H. D., Nayler W. G. Plasma ionized calcium in hypomagnesaemia. Br Med J. 1968 Mar 9;1(5592):622–623. doi: 10.1136/bmj.1.5592.622. [DOI] [PMC free article] [PubMed] [Google Scholar]