Skip to main content
PMC home page
British Medical Journal logoLink to British Medical Journal
. 1970 May 16;2(5706):402–404. doi: 10.1136/bmj.2.5706.402

Practolol in Treatment of Angina Pectoris. A Double-blind Trial

C F George, R E Nagle, B L Pentecost
PMCID: PMC1700308  PMID: 4392984

Abstract

Twenty-four patients with angina pectoris entered a double-blind trial of the cardioselective beta-adrenergic blocking agent practolol. Seventeen experienced less angina and consumed fewer glyceryl trinitrate tablets when on the active preparation. There was also a decrease in the mean number of attacks suffered by patients while on practolol and a reduction in the number of glyceryl trinitrate tablets taken. These results are of statistical significance at, at least, the 5% level.

Full text

PDF
404

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Dunlop D., Shanks R. G. Selective blockade of adrenoceptive beta receptors in the heart. Br J Pharmacol Chemother. 1968 Jan;32(1):201–218. doi: 10.1111/j.1476-5381.1968.tb00444.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Fitzgerald J. D., Scales B. Effect of a new adrenergic beta-blocking agent (ICI 50,172) on heart rate in relation to its blood levels. Int Z Klin Pharmakol Ther Toxikol. 1968;1(6):467–474. [PubMed] [Google Scholar]
  3. GILLAM P. M., PRICHARD B. N. USE OF PROPRANOLOL IN ANGINA PECTORIS. Br Med J. 1965 Aug 7;2(5457):337–339. doi: 10.1136/bmj.2.5457.337. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Gianelly R. E., Goldman R. H., Treister B., Harrison D. C. Propranolol in patients with angina pectoris. Ann Intern Med. 1967 Dec;67(6):1216–1225. doi: 10.7326/0003-4819-67-6-1216. [DOI] [PubMed] [Google Scholar]
  5. Grant R. H., Keelan P., Kernohan R. J., Leonard J. C., Nancekievill L., Sinclair K. Multicenter trial of propranolol in angina pectoris. Am J Cardiol. 1966 Sep;18(3):361–365. doi: 10.1016/0002-9149(66)90054-3. [DOI] [PubMed] [Google Scholar]
  6. KEELAN P. DOUBLE-BLIND TRIAL OF PROPRANOLOL (INDERAL) IN ANGINA PECTORIS. Br Med J. 1965 Apr 3;1(5439):897–898. doi: 10.1136/bmj.1.5439.897. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Macdonald A. G., Ingram C. G., McNeill R. S. The effect of propranolol on airway resistance. Br J Anaesth. 1967 Dec;39(12):919–926. doi: 10.1093/bja/39.12.919. [DOI] [PubMed] [Google Scholar]
  8. Macdonald A. G., McNeill R. S. A comparison of the effect on airway resistance of a new beta blocking drug, ICI.50,172 and propranolol. Br J Anaesth. 1968 Jul;40(7):508–510. doi: 10.1093/bja/40.7.508. [DOI] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES