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British Medical Journal logoLink to British Medical Journal
. 1970 Jun 27;2(5712):752–754. doi: 10.1136/bmj.2.5712.752

Autoimmunization with Irradiated Tumour Cells in Human Malignant Melanoma

R L Ikonopisov, M G Lewis, I D Hunter-Craig, D C Bodenham, T M Phillips, C I Cooling, J Proctor, G Hamilton Fairley, P Alexander
PMCID: PMC1700876  PMID: 4913783

Abstract

Thirteen patients have been immunized with their own irradiated melanoma cells on one or more occasions. Following these autografts tumour-specific cytotoxic antibodies were produced, the longest response lasting 14 days. This procedure had no apparent effect on the course of the disease in these patients.

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