Skip to main content
British Journal of Pharmacology and Chemotherapy logoLink to British Journal of Pharmacology and Chemotherapy
. 1963 Aug;21(1):67–77. doi: 10.1111/j.1476-5381.1963.tb01502.x

Balanced incomplete block designs in biological assay illustrated by the assay of gastrin using a youden square

D Colquhoun
PMCID: PMC1703851  PMID: 14066152

Abstract

General equations are given for computing the results of any (j+j) dose parallel line biological assay based on an incomplete block design. Only the information from comparisons within blocks is used. The computation is illustrated numerically by means of a (2+2) assay of gastrin devised and performed by Lai (1962), in which only three of the four doses could be given to each animal.

Full text

PDF
72

Articles from British Journal of Pharmacology and Chemotherapy are provided here courtesy of The British Pharmacological Society

RESOURCES