Abstract
Between 1942 and 1978 radiation therapy was given to 362 patients with seminoma of the testis, 40 (11%) of whom had a history of maldescent of either testis. The disease was classified retrospectively according to the extent of the primary tumor, the involvement of the regional lymph nodes and the presence of distant metastases (the TNM system), and the results of treatment were analysed according to the classifications. Among the 275 patients referred for treatment at least 5 years before this analysis the 5-year survival rates were 87% overall, 96% for those with a T1 or T2 (relatively localized) tumour but no evidence of nodal involvement or distant metastases and 62% for the 24 with palpable or distant metastases at the time of clinical presentation. Of the 28 patients in whom the disease recurred 15 were successfully treated. A second primary testicular tumour developed in the contralateral testis of eight patients. The incidence of other cancers was not increased over the expected rate in the general male population of the same age.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Angulo R., Caballero L., Mejia P. Bilateral seminoma 34 years after orchiopexy. J Urol. 1977 Nov;118(5):882–882. doi: 10.1016/s0022-5347(17)58235-x. [DOI] [PubMed] [Google Scholar]
- Coldman A. J., Elwood J. M. Examining survival data. Can Med Assoc J. 1979 Oct 20;121(8):1065-8, 1071. [PMC free article] [PubMed] [Google Scholar]
- Doornbos J. F., Hussey D. H., Johnson D. E. Radiotherapy for pure seminoma of the testis. Radiology. 1975 Aug;116(02):401–404. doi: 10.1148/116.2.401. [DOI] [PubMed] [Google Scholar]
- Gehring G. G., Rodriguez F. R., Woodhead D. M. Malignant degeneration of cryptorchid testes following orchiopexy. J Urol. 1974 Sep;112(3):354–356. doi: 10.1016/s0022-5347(17)59729-3. [DOI] [PubMed] [Google Scholar]
- Maier J. G., Sulak M. H. Proceedings: Radiation therapy in malignant testis tumors. I: Seminoma; II: Carcinoma. Cancer. 1973 Nov;32(5):1212–1216. doi: 10.1002/1097-0142(197311)32:5<1212::aid-cncr2820320530>3.0.co;2-7. [DOI] [PubMed] [Google Scholar]
- Peckham M. J., McElwain T. J. Testicular tumours. Clin Endocrinol Metab. 1975 Nov;4(3):665–692. doi: 10.1016/s0300-595x(75)80052-1. [DOI] [PubMed] [Google Scholar]
- van der Werf-Messing B. Radiotherapeutic treatment of testicular tumors. Int J Radiat Oncol Biol Phys. 1976 Jan-Feb;1(3-4):235–248. doi: 10.1016/0360-3016(76)90045-6. [DOI] [PubMed] [Google Scholar]