Skip to main content
Applied and Environmental Microbiology logoLink to Applied and Environmental Microbiology
. 1977 Jan;33(1):211–212. doi: 10.1128/aem.33.1.211-212.1977

Production of cyclopiazonic acid by Aspergillus flavus Link.

K C Luk, B Kobbe, J M Townsend
PMCID: PMC170627  PMID: 402112

Abstract

Production of cyclopiazonic acid by Aspergillus flavus is reported for the first time. A procedure for its production by agitated solid substrate fermentation on red wheat is described along with the isolation procedure and physical and chemical properties of this indole derivative. The compound has been found to exert antibacterial activity.

Full text

PDF
211

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Demain A. L., Hunt N. A., Malik V., Kobbe B., Hawkins H., Matsuo K., Wogan G. N. Improved procedure for production of cytochalasin E and tremorgenic mycotoxins by Aspergillus clavatus. Appl Environ Microbiol. 1976 Jan;31(1):138–140. doi: 10.1128/aem.31.1.138-140.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Holzapfel C. W. The isolation and structure of cyclopiazonic acid, a toxic metabolite of Penicillium cyclopium Westling. Tetrahedron. 1968 Mar;24(5):2101–2119. doi: 10.1016/0040-4020(68)88113-x. [DOI] [PubMed] [Google Scholar]
  3. Purchase I. F. The acute toxicity of the mycotoxin cyclopiazonic acid to rats. Toxicol Appl Pharmacol. 1971 Jan;18(1):114–123. doi: 10.1016/0041-008x(71)90320-6. [DOI] [PubMed] [Google Scholar]

Articles from Applied and Environmental Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES