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. 1981 Mar;37(3):1094–1098. doi: 10.1128/jvi.37.3.1094-1098.1981

Nucleotide sequence changes in polyoma virus A gene mutants.

T Thomas, P Vollmer, W R Folk
PMCID: PMC171111  PMID: 6262530

Abstract

The mutational alterations in polyoma virus mutants ts-a and ts-25E which cause their large T-antigens to be thermolabile have been identified. In ts-a, a G leads to A transition at nucleotide 2193 causes the replacement of Ala (GCT) by Thr (ACT). In ts-25E, a G leads to T transversion at nucleotide 2883 causes the replacement of Gly (GGC) by Cys (TGC). Revertants of both mutants have been isolated and shown to have the original nucleotides restored at these positions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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